Consultant Clark and Daughtrey LLP
Internal Medicine
Dr. Bruce A. Kottke, MD
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Bruce A. Kottke, MD is an expert in the field of Internal Medicine. He researched medicine at University of Minnesota Medical School. University of Minnesota Medical School is ranked 40 in research and 10 in primary care medicine He over the years received 2 awards: "Meaningful Use Stage 1 Certification" and "Fellow (FACC)". Bruce Kottke is a published MD as well. He has 101 publications published. The latest was: Very-low-density lipoprotein subfraction composition and metabolism by adipose tissue.
Publications
- The ultimate solution to the problem of aspirin resistance.
- Population genetics of apolipoproteins A-IV, E, and H, and the angiotensin converting enzyme (ACE): associations with lipids, and apolipoprotein levels in American Sam...
- Problems in the measurement of Lp(a) (millimoles per liter versus milligrams percent).
- Executive Summary: Pivotal Research in Cardiovascular Syndromes in the Elderly.
- Very-low-density lipoprotein subfraction composition and metabolism by adipose tissue.
- The effect of the treatment of hypothyroidism and hyperthyroidism on plasma lipids and apolipoproteins AI, AII and E.
- HDL subparticles and coronary artery disease in NIDDM.
- Overview of lipoprotein metabolism: mechanisms involved and conveying this information to patients.
- Increase in total plasma homocysteine concentration after cardiac transplantation.
- The ineffectiveness of a commonly recommended diet for lowering total and low-density lipoprotein cholesterol levels.
- The role of lipoprotein A-I and lipoprotein A-I/A-II in predicting coronary artery disease.
- Serum lipid responses to a eucaloric high-complex carbohydrate diet in different obesity phenotypes.
- A fluorescence-conjugated immunobinding assay for the detection of P-selectin on platelets.
- Effect of heparin-binding growth factor-1 on bronchial healing in canine lung allograft transplantation.
- Lipids and Lp(a) lipoprotein levels and coronary artery disease in subjects with non-insulin-dependent diabetes mellitus.
- Lipoproteins and apolipoproteins. Making use of their metabolic properties to individualize therapy.
- Immunomagnetic separation of subpopulations of apolipoprotein A-I.
- Identification and quantification of apolipoproteins in addition to apo[a] and apo B-100 in human lipoprotein[a].
- A particle concentration fluorescence immunoassay for Lp(a).
- Lipoprotein compositional changes in the fasting and postprandial state on a high-carbohydrate low-fat and a high-fat diet in subjects with noninsulin-dependent diabet...
- Treatment of and screening for hyperlipidemia.
- Current understanding of the mechanisms of atherogenesis.
- Very low density lipoprotein subfraction apolipoprotein composition.
- Quantification of human plasma apolipoproteins C-I, C-II, and C-III by radioimmunoassays.
- Apolipoprotein A-II levels and coronary artery disease in subjects with and without diabetes: a study with use of a specific radioimmunoassay for apolipoprotein A-II.
- Separation of high-density lipoproteins into apolipoprotein E-poor and apolipoprotein E-rich subfractions by fast protein liquid chromatography using a heparin affinit...
- Insulinemia in children at low and high risk of NIDDM.
- Population genetics of apolipoprotein A-4, E, and H polymorphisms in Yanomami Indians of northwestern Brazil: associations with lipids, lipoproteins, and carbohydrate ...
- Differential health benefits of weight loss in upper-body and lower-body obese women.
- The gender-specific apolipoprotein E genotype influence on the distribution of plasma lipids and apolipoproteins in the population of Rochester, Minnesota. II. Regress...
- Apolipoprotein B quantified by particle-concentration fluorescence immunoassay.
- Acute physical exercise alters apolipoprotein E and C-III concentrations of apo E-rich very low density lipoprotein fraction.
- Low-dose, time-release nicotinic acid: effects in selected patients with low concentrations of high-density lipoprotein cholesterol.
- Hypercholesterolemia and atherosclerosis in primary biliary cirrhosis: what is the risk?
- Estimation of the frequency of isoform-genotype discrepancies at the apolipoprotein E locus in heterozygotes for the isoforms.
- The gender-specific apolipoprotein E genotype influence on the distribution of lipids and apolipoproteins in the population of Rochester, MN. I. Pleiotropic effects on...
- Levels of lipids, lipoproteins, and apolipoproteins in a defined population.
- Expressed hypervariable polymorphism of apolipoprotein (a).
- Lipoprotein analysis in the evaluation of chest pain in the emergency department.
- Effects of polymorphisms in apolipoproteins E, A-IV, and H on quantitative traits related to risk for cardiovascular disease.
- ApoA-I secretion by rabbit intestinal mucosa cell cultures.
- Predictors of intracranial carotid artery atherosclerosis. Duration of cigarette smoking and hypertension are more powerful than serum lipid levels.
- Effect of coconut oil on plasma apo A-I levels in WHHL and NZW rabbits.
- Serum lipids and lipoproteins are less powerful predictors of extracranial carotid artery atherosclerosis than are cigarette smoking and hypertension.
- Niacin-induced hepatitis: a potential side effect with low-dose time-release niacin.
- Rapid regulation of apolipoprotein A-I secretion in HepG2 cells by a factor associated with bovine high-density lipoproteins.
- Lipid and apolipoprotein levels in six Solomon Island societies differ from those in a U.S. white population.
- The effects of generation and gender on the joint distributions of lipid and apolipoprotein phenotypes in the population at large.
- Effect of 25-hydroxycholesterol and bile acids on the regulation of cholesterol metabolism in Hep G2 cells.
- Evaluation of arterialized vein graft permeability with Evans blue dye and iodine 125-labeled albumin.
- Lipoprotein-mediated efflux of radiolabeled cholesterol from cells does not indicate net removal of cellular cholesterol mass.
- Smoking and reverse cholesterol transport: evidence for gene-environment interaction.
- Studies on the regulation of cholesterol metabolism by low- and high-density lipoproteins in HepG2 cells.
- Genetic determination of plasma apolipoprotein AI in a population-based sample.
- Genetic studies of human apolipoproteins. V. A novel rapid procedure to screen apolipoprotein E polymorphism.
- The beta very low density lipoprotein present in hepatic lipase deficiency competitively inhibits low density lipoprotein binding to fibroblasts and stimulates fibrobl...
- Management of lipids in primary and secondary prevention of cardiovascular diseases.
- Studies on the effect of storage of normolipidemic plasma on the metabolism of very-low-density lipoprotein cholesterol in human skin fibroblasts.
- Familial hypercholesterolemia with unusual foamy histiocytes. Report of a case with myelophthisic anemia and xanthoma of the maxillary sinus.
- Hypercholesterolemia and atherosclerosis: present and future therapy including LDL-apheresis.
- Cholestyramine treatment in early life of low-density lipoprotein receptor deficient Watanabe rabbits: decreased aortic cholesteryl ester accumulation and atherosclero...
- Partitioning the variability of fasting plasma glucose levels in pedigrees. Genetic and environmental factors.
- Role of macrophages in lipid metabolism.
- Metabolism of apolipoprotein E-containing human plasma lipoproteins by rat and human cells in culture.
- Sterol excretion and cholesterol absorption in diabetics and nondiabetics with and without hyperlipidemia.
- A rapid apolipoprotein E radioimmunoassay using solid-phase staphylococcus protein. Use of pooled plasma as a secondary standard.
- Quantification and immunolocalization of apolipoprotein E in experimental atherosclerosis.
- Use of a quality-control plasma sample to decrease interassay variation in radioimmunoassays of apolipoprotein A-I.
- Apolipoproteins and coronary artery disease.
- Plasma lipids and apolipoprotein A-I and A-II levels in alcoholic patients.
- Univariate and bivariate analyses of cholesterol and triglyceride levels in pedigrees.
- The genetic determination of plasma apolipoprotein A-I levels measured by radioimmunoassay: a study of high-risk pedigrees.
- Metabolism of glycosylated very-low-density lipoproteins in human skin fibroblasts.
- Lipid markers for atherosclerosis.
- Postprandial distribution of apolipoproteins C-II and C-III in normal subjects and patients with mild hypertriglyceridemia: comparison of meals containing corn oil and...
- Monoclonal antibodies can precipitate low-density lipoprotein. II. Radioimmunoassays with single and combined monoclonal antibodies for determining apolipoprotein B in...
- Interaction of normolipidemic very low density lipoproteins with receptors in human skin fibroblasts.
- Structure and function of human low density lipoproteins. Studies using proteolytic cleavage by plasma kallikrein.
- Human breast milk stimulates prostaglandin synthesis in cultured human skin fibroblasts.
- Human breast milk stimulates low density lipoprotein (LDL) binding to human skin fibroblasts in culture.
- Acute effects of a glucose load on plasma apolipoproteins A-I, A-II, C-II, and C-III in normal and non-insulin-dependent diabetic men.
- Primary hypercholesterolemia: effect of treatment on serum lipids, lipoprotein fractions, cholesterol absorption, sterol balance, and platelet aggregation.
- Detection of genetic heterogeneity among pedigrees through complex segregation analysis: an application to hypercholesterolemia.
- Analysis of plasma lipids and apolipoproteins in insulin-dependent and noninsulin-dependent diabetics.
- Monoclonal antibodies to human plasma low-density lipoproteins. I. Enhanced binding of 125I-labeled low-density lipoproteins by combined use of two monoclonal antibodies.
- Apolipoprotein A-I as a marker of angiographically assessed coronary-artery disease.
- Total cholesterol and lipoproteins in school children: prediction of coronary heart disease in adult relatives.
- Cholesterol excretion studies in familial hypercholesterolemic children and their normolipidemic siblings.
- Biochemical genetics of LDL receptor mutations in familial hypercholesterolemia.
- Cannabinoids impair the formation of cholesteryl ester in cultured human cells.
- Improved method for determination of triglycerides in plasma lipoproteins by an enzymic kit method.
- Immunochemistry of human plasma apolipoprotein C-II as studied by radioimmunoassay.
- Plasma lipid and apoprotein levels following plasmapheresis in a subject homozygous for familial hypercholesterolemia.
- Association of risk factor variables and coronary artery disease documented with angiography.
- Postprandial exchange of apolipoprotein C-III between plasma lipoproteins.
- Heterozygous defects in alpha 1-antitrypsin and low-density lipoprotein receptor. Simultaneous occurrence in a pediatric patient.
- Regional aortic differences in atherosclerosis-susceptibility: changes in prostaglandin biosynthesis and cholesterol accumulation in response to desoxycorticosterone (...
- Tween-20 increases the immunoreactivity of apolipoprotein A-I in plasma.
- Physical, chemical, and immunochemical studies of apolipoprotein A-I from pigeon plasma high density lipoproteins.
- Effect of probucol on cholesterol metabolism in the rat.
Schools
University Of Minnesota Medical School
Indianapolis Genl Hospital
Mayo Foundation For Med Education and Research
Doctors Specialties
- Internal Medicine
Accepted Insurances
Awards
- Meaningful Use Stage 1 Certification
- Fellow (FACC)
Education
-
Mayo School of Graduate Medical Education -
University of Minnesota Medical School
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