Associate Professor of Pediatrics, Boston Children's Hospital
Pediatric Emergency Medicine
Dr. Bruce H. Horwitz, MD
|
|
Give Review
Doctor Bruce H. Horwitz, MD practices Pediatric Emergency Medicine. He researched medicine at Yale University School of Medicine. Yale University School of Medicine is a top medical university. Yale University School of Medicine is ranked 7/57 in Research/PrimaryCare. Doctor Bruce H. Horwitz, MD is also published. He has 38 publications published. The lastest publication: "The p65 subunit of NF-kappa B is redundant with p50 during B cell proliferative responses, and is required for germline CH transcription and class switching to IgG3.' He accepts Medicare payments and is listed with Medicare.gov.
Publications
- O-005 YI Microbiota Drives Inflammation by Altering Intestinal Lamina Propria Macrophage Phenotype in a Novel IL10R-Deficient Model of Very Early Onset IBD.
- Interleukin-10 receptor signaling in innate immune cells regulates mucosal immune tolerance and anti-inflammatory macrophage function.
- Endothelial TNF Receptor 2 Induces IRF1 Transcription Factor-Dependent Interferon-? Autocrine Signaling to Promote Monocyte Recruitment.
- Wiskott-Aldrich Syndrome Protein Deficiency in Innate Immune Cells Leads to Mucosal Immune Dysregulation and Colitis in Mice.
- Nfkb1 inhibits LPS-induced IFN-β and IL-12 p40 production in macrophages by distinct mechanisms.
- NF-κB1 inhibits TLR-induced IFN-β production in macrophages through TPL-2-dependent ERK activation.
- Unifying roles for regulatory T cells and inflammation in cancer.
- Cytotoxic-T-lymphocyte-associated antigen 4 blockade abrogates protection by regulatory T cells in a mouse model of microbially induced innate immune-driven colitis.
- c-Rel is essential for the development of innate and T cell-induced colitis.
- The straw that stirs the drink: insight into the pathogenesis of inflammatory bowel disease revealed through the study of microflora-induced inflammation in geneticall...
- Inhibition of Helicobacter hepaticus-induced colitis by IL-10 requires the p50/p105 subunit of NF-kappa B.
- Innate immune inflammatory response against enteric bacteria Helicobacter hepaticus induces mammary adenocarcinoma in mice.
- Defective activation of ERK in macrophages lacking the p50/p105 subunit of NF-kappaB is responsible for elevated expression of IL-12 p40 observed after challenge with ...
- Proinflammatory CD4+ CD45RB(hi) lymphocytes promote mammary and intestinal carcinogenesis in Apc(Min/+) mice.
- A role for NF-kappa B subunits p50 and p65 in the inhibition of lipopolysaccharide-induced shock.
- Gastroenteritis in NF-kappaB-deficient mice is produced with wild-type Camplyobacter jejuni but not with C. jejuni lacking cytolethal distending toxin despite persiste...
- CD4(+)CD25(+) regulatory lymphocytes require interleukin 10 to interrupt colon carcinogenesis in mice.
- NF-kappa B is required within the innate immune system to inhibit microflora-induced colitis and expression of IL-12 p40.
- CD4+ CD25+ regulatory T lymphocytes inhibit microbially induced colon cancer in Rag2-deficient mice.
- Interleukin 10 receptor signaling: master regulator of intestinal mucosal homeostasis in mice and humans.
- Pathogenic Intestinal Bacteria Enhance Prostate Cancer Development via Systemic Activation of Immune Cells in Mice.
- Serum markers in acute appendicitis.
- Mechanisms of granulocytosis in the absence of CD18.
- Discovery and validation of urine markers of acute pediatric appendicitis using high-accuracy mass spectrometry.
- Acute appendicitis is characterized by a uniform and highly selective pattern of inflammatory gene expression.
- Effects of CD18 deficiency on the emigration of murine neutrophils during pneumonia.
- Nuclear factor kappa B is required for the development of marginal zone B lymphocytes.
- Failure of lymphopoiesis after adoptive transfer of NF-kappaB-deficient fetal liver cells.
- Induction of activation-induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkappaB.
- NF-kappa B, an inhibitor of microflora-induced colitis.
- Targeted mutation of TNF receptor I rescues the RelA-deficient mouse and reveals a critical role for NF-kappa B in leukocyte recruitment.
- Helicobacter hepaticus infection in mice: models for understanding lower bowel inflammation and cancer.
- The p65 subunit of NF-kappa B is redundant with p50 during B cell proliferative responses, and is required for germline CH transcription and class switching to IgG3.
- Typhlocolitis in NF-kappa B-deficient mice.
- Regulation of PD-1, PD-L1, and PD-L2 expression during normal and autoimmune responses.
- Rapid reversal of interleukin-6-dependent epithelial invasion in a mouse model of microbially induced colon carcinoma.
- NF-kappaB p50 and p65 subunits control intestinal homeostasis.
Schools
Yale University
Boston Children39s Hospital
Doctors Specialties
- Pediatric Emergency Medicine
Accepted Insurances
Education
-
Boston Children's Hospital -
Yale University School of Medicine
Hospital
-
Boston Children's Hospital -
South Shore Hospital
Helpful Reviews
Similar Doctors
|
|
Dr. Anne M. Stack, MD
 This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Sonal N. Shah, MD |
|
|
Dr. Sara A. Schutzman, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Lauren M. Allister, MD |
|
|
Dr. Stephen C. Porter, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Michael P. Goldman, MD |
|
|
Dr. Pradip P. Chaudhari, MD |
|
|
Dr. Sonia Lewin, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Elliot Melendez, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. David H. Dorfman, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Daniela C. Ramirez-Schrempp, MD
This Doctor is OpenDoctor Recommended.
|