Professor of Pathology, Professor of Oncology, Associate Professor of Ophthalmology, Johns Hopkins University School of Medicine; Director, Ophthalmic Pathology
Pathology
Dr. Charles G. Eberhart, MD
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Charles Eberhart is an expert in the field of Pathology. He attended University of Texas Southwestern Medical School. He has 1 awards "Elected Member". Charles Eberhart has written publications. He has 100 publications published with PubMed. The lastest paper is: 'Altered gene expression in conjunctival squamous cell carcinoma.' Charles G. Eberhart accepts Medicare payments and is registered with Medicare.gov.
Publications
- Altered gene expression in conjunctival squamous cell carcinoma.
- Analysis of Varicella-Zoster Virus in Temporal Arteries Biopsy Positive and Negative for Giant Cell Arteritis.
- Somatic cell transfer of c-Myc and Bcl-2 induces large-cell anaplastic medulloblastomas in mice.
- Clinicopathologic implications of NF1 gene alterations in diffuse gliomas.
- Highly PEGylated DNA Nanoparticles Provide Uniform and Widespread Gene Transfer in the Brain.
- Corticosteroid-loaded biodegradable nanoparticles for prevention of corneal allograft rejection in rats.
- The chromatin-modifying protein HMGA2 promotes atypical teratoid/rhabdoid cell tumorigenicity.
- Notch signaling activation in pediatric low-grade astrocytoma.
- Molecular pathways: not a simple tube--the many functions of blood vessels.
- Identification of Multiple DNA Copy Number Alterations Including Frequent 8p11.22 Amplification in Conjunctival Squamous Cell Carcinoma.
- A model of a patient-derived IDH1 mutant anaplastic astrocytoma with alternative lengthening of telomeres.
- DNMT-dependent suppression of microRNA regulates the induction of GBM tumor-propagating phenotype by Oct4 and Sox2.
- Management of Pediatric and Adult Patients with Medulloblastoma.
- On the origin of 'guttae'
- International Society of Neuropathology-Haarlem Consensus Guidelines, for Nervous System Tumor Classification and Grading.
- An 80-year experience with optic nerve glioma cases at the armed forces institute of pathology: evolution from museum to molecular evaluation suggests possibe interven...
- Phase II study of sorafenib in children with recurrent or progressive low-grade astrocytomas.
- RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation.
- Intraocular tuberculosis presenting as a large anterior chamber mass.
- Notch signaling in prostate cancer: A moving target.
- Genetic Profiling by Single-Nucleotide Polymorphism-Based Array Analysis Defines Three Distinct Subtypes of Orbital Meningioma.
- Long Interspersed Element-1 Protein Expression Is a Hallmark of Many Human Cancers.
- Fuchs Endothelial Corneal Dystrophy: A Neurodegenerative Disorder?
- Activation of mTORC1/mTORC2 signaling in pediatric low-grade glioma and pilocytic astrocytoma reveals mTOR as a therapeutic target.
- DNA Mismatch Repair Defects and Microsatellite Instability Status in Periocular Sebaceous Carcinoma.
- NRF2 plays a protective role in diabetic retinopathy in mice.
- NY-ESO-1 Expression in Meningioma Suggests a Rationale for New Immunotherapeutic Approaches.
- Inhibition of monocarboxylate transporter-4 depletes stem-like glioblastoma cells and inhibits HIF transcriptional response in a lactate-independent manner.
- 5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft.
- Morphologic characteristics and immunohistochemical profile of diffuse intrinsic pontine gliomas.
- A glioblastoma neurosphere line with alternative lengthening of telomeres.
- Hypoxic retinal Muller cells promote vascular permeability by HIF-1-dependent up-regulation of angiopoietin-like 4.
- cMYC expression in infiltrating gliomas: associations with IDH1 mutations, clinicopathologic features and outcome.
- Beta-amyloid, Phospho-tau and Alpha-synuclein Deposits Similar to Those in The Brain Are Not Identified in The Eyes of Alzheimer's and Parkinson's Disease Patients.
- Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1.
- Tissue microarray analysis of cyclin-dependent kinase inhibitors p21 and p16 in Fuchs dystrophy.
- Endothelial cell whole genome expression analysis in a mouse model of early-onset fuchs' endothelial corneal dystrophy.
- Combination of paclitaxel thermal gel depot with temozolomide and radiotherapy significantly prolongs survival in an experimental rodent glioma model.
- A broad survey of cathepsin k immunoreactivity in human neoplasms.
- Three-dimensional amide proton transfer MR imaging of gliomas: Initial experience and comparison with gadolinium enhancement.
- L450W and Q455K Col8a2 Knock-in Mouse Models of Fuchs Endothelial Corneal Dystrophy Show Distinct Phenotypes and Evidence for Altered Autophagy.
- CD133/CD15 defines distinct cell subpopulations with differential in vitro clonogenic activity and stem cell-related gene expression profile in in vitro propagated gli...
- A role for Jag2 in promoting uveal melanoma dissemination and growth.
- MicroRNA profiling in pediatric pilocytic astrocytoma reveals biologically relevant targets, including PBX3, NFIB, and METAP2.
- Pathological and molecular advances in pediatric low-grade astrocytoma.
- Molecular and Morphologic Correlates of the Alternative Lengthening of Telomeres Phenotype in High Grade Astrocytomas.
- Chronic hypotony associated with the Boston type 1 keratoprosthesis.
- Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma.
- Nature versus Nurture in Glioblastoma: Microenvironment and Genetics Can Both Drive Mesenchymal Transcriptional Signature.
- Notch Signaling Promotes Growth and Invasion in Uveal Melanoma.
- BRAF Alterations in Primary Glial and Glioneuronal Neoplasms of the Central Nervous System With Identification of 2 Novel KIAA1549: BRAF Fusion Variants.
- Molecular subgroups of medulloblastoma: the current consensus.
- Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples.
- A novel polymer gel for the delivery of local therapies to intracranial tumors: In vivo safety evaluation.
- Prevalence of the Alternative Lengthening of Telomeres Telomere Maintenance Mechanism in Human Cancer Subtypes.
- Altered Telomeres in Tumors with ATRX and DAXX Mutations.
- c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype.
- Yes-Associated Protein 1 Is Widely Expressed in Human Brain Tumors and Promotes Glioblastoma Growth.
- BRAF Activation Induces Transformation and Then Senescence in Human Neural Stem Cells: A Pilocytic Astrocytoma Model.
- A mouse model of blast injury to brain: initial pathological, neuropathological, and behavioral characterization.
- Transforming growth factor-? signaling pathway activation in Keratoconus.
- Nrf2 has a protective role against neuronal and capillary degeneration in retinal ischemia-reperfusion injury.
- Medulloblastoma comprises four distinct molecular variants.
- Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome.
- Diagnosis of intravascular lymphoma by a novel biopsy site.
- A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors.
- Notch3 activation promotes invasive glioma formation in a tissue site-specific manner.
- Krüppel-like family of transcription factor 9, a differentiation-associated transcription factor, suppresses Notch1 signaling and inhibits glioblastoma-initiating stem...
- The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance.
- Spectrum of pilomyxoid astrocytomas: intermediate pilomyxoid tumors.
- KLF9, A Differentiation-Associated Transcription Factor, Suppresses Notch1 Signaling and Inhibits Glioblastoma-Initiating Stem Cells.
- Human hedgehog interacting protein expression and promoter methylation in medulloblastoma cell lines and primary tumor samples.
- Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres.
- NKX3.1 as a marker of prostatic origin in metastatic tumors.
- Establishment of a human glioblastoma stemlike brainstem rodent tumor model.
- Ocular MECP2 protein expression in patients with and without Rett syndrome.
- Intraorbital meningiomas: a pathologic review using current World Health Organization criteria.
- High-risk medulloblastoma: does c-myc amplification overrule histopathology?
- Induction of ectopic Myc target gene JAG2 augments hypoxic growth and tumorigenesis in a human B-cell model.
- Unfolded protein response in fuchs endothelial corneal dystrophy: a unifying pathogenic pathway?
- NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts.
- Ultrasound features of orbital granular cell tumor.
- DNER, an epigenetically modulated gene, regulates glioblastoma-derived neurosphere cell differentiation and tumor propagation.
- Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer.
- A clinicopathologic series of primary graft failure after Descemet's stripping and automated endothelial keratoplasty.
- Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma.
- Iris cross-sectional area decreases with pupil dilation and its dynamic behavior is a risk factor in angle closure.
- Tissue inhibitor of matrix metalloproteinase-3 levels in the extracellular matrix of lung, kidney, and eye increase with age.
- Embryonal tumors with abundant neuropil and true rosettes: a distinctive CNS primitive neuroectodermal tumor.
- Gene expression profiling of NF-1-associated and sporadic pilocytic astrocytoma identifies aldehyde dehydrogenase 1 family member L1 (ALDH1L1) as an underexpressed can...
- Just say no to ATOH: how HIC1 methylation might predispose medulloblastoma to lineage addiction.
- Hepatocyte growth factor and sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth.
- Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors.
- Coexpression of neuronatin splice forms promotes medulloblastoma growth.
- Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma.
- Even cancers want commitment: lineage identity and medulloblastoma formation.
- Medulloblastoma stem cells.
- Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma.
- The Smo/Smo model: hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread.
Schools
University of Texas Southwestern Medical Center At Dallas
Johns Hopkins University School Med
Doctors Specialties
- Neuropathology
- Pathology
Accepted Insurances
Awards
- Elected Member
Education
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Johns Hopkins University -
University of Texas Southwestern Medical School
Hospital
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Howard County General Hospital -
Johns Hopkins Bayview Medical Center -
Johns Hopkins Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1821039454 |
| Last Name Of The Provider | EBERHART |
| First Name Of The Provider | CHARLES |
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