Physician

Internal Medicine

Colin Ohrt works in the field of Internal Medicine. Colin Ohrt has written publications. He has 33 publications published with PubMed. The lastest paper is: 'Efficacy and tolerance of extended-dose halofantrine for drug-resistant falciparum malaria in Thailand.'

Publications

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• The Pharmacokinetics and Pharmacodynamics of (+) and (-) Primaquine Enantiomers in Rhesus macaques (Macaca mulatta).
• Primaquine Enantiomers: Scalable Preparation and Differential Pharmacologic and Toxicologic Profiles.
• Causal Prophylactic Efficacy of Primaquine, Tafenoquine and Atovaquone-Proguanil against Plasmodium cynomolgi in Rhesus Monkey Model.
• Humanized mouse model of glucose 6-phosphate dehydrogenase deficiency for in vivo assessment of hemolytic toxicity.
• An In vivo Drug Screening Model Using Glucose-6-Phosphate Dehydrogenase Deficient Mice to Predict the Hemolytic Toxicity of 8-Aminoquinolines.
• Anti-relapse activity of mirincamycin in the Plasmodium cynomolgi sporozoite-infected Rhesus monkey model.
• CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine.
• Efficacy and tolerance of extended-dose halofantrine for drug-resistant falciparum malaria in Thailand.
• Randomised placebo-controlled trial of primaquine for prophylaxis of falciparum and vivax malaria.
• Achieving compliance with influenza immunization of medical house staff and students. A randomized controlled trial.
• Antimalarial Activity of 9a-N Substituted 15-Membered Azalides with Improved in Vitro and in Vivo Activity over Azithromycin.
• Review: Improving the therapeutic index of 8-aminoquinolines by the use of drug combinations: review of the literature and proposal for future investigations.
• Absolute bioavailability of cis-mirincamycin and trans-mirincamycin in healthy rhesus monkeys and ex vivo antimalarial activity against Plasmodium falciparum.
• Radical curative efficacy of tafenoquine combination regimens in Plasmodium cynomolgi-infected Rhesus monkeys (Macaca mulatta).
• Plasmodium falciparum Infection during Suppressive Prophylaxis with Mefloquine Does Not Induce an Antibody Response to Merozoite Surface Protein-1(42).
• Synthesis, structure-activity relationship, and antimalarial activity of ureas and thioureas of 15-membered azalides.
• An automated, polymer-assisted strategy for the preparation of urea and thiourea derivatives of 15-membered azalides as potential antimalarial chemotherapeutics.
• Antimalarial activity of novel 5-aryl-8-aminoquinoline derivatives.
• Randomized, double-blind study of the safety, tolerability, and efficacy of tafenoquine versus mefloquine for malaria prophylaxis in nonimmune subjects.
• A randomized, double-blind, safety and tolerability study to assess the ophthalmic and renal effects of tafenoquine 200 mg weekly versus placebo for 6 months in health...
• Clinical development of new prophylactic antimalarial drugs after the 5th Amendment to the Declaration of Helsinki.
• Changes in the total leukocyte and platelet counts in Papuan and non Papuan adults from northeast Papua infected with acute Plasmodium vivax or uncomplicated Plasmodiu...
• Pilot assessment of the sensitivity of the malaria thin film.
• Establishing a malaria diagnostics centre of excellence in Kisumu, Kenya.
• In vitro antimalarial activity of azithromycin, artesunate, and quinine in combination and correlation with clinical outcome.
• Azithromycin combination therapy with artesunate or quinine for the treatment of uncomplicated Plasmodium falciparum malaria in adults: a randomized, phase 2 clinical ...
• Systematic comparison of two methods to measure parasite density from malaria blood smears.
• Effective treatment of uncomplicated Plasmodium falciparum malaria with azithromycin-quinine combinations: a randomized, dose-ranging study.
• Tolerability of azithromycin as malaria prophylaxis in adults in northeast papua, indonesia.
• Assessing the Parasight-F test in northeastern Papua, Indonesia, an area of mixed Plasmodium falciparum and Plasmodium vivax transmission.
• Impact of microscopy error on estimates of protective efficacy in malaria-prevention trials.
• Assessment of azithromycin in combination with other antimalarial drugs against Plasmodium falciparum in vitro.

Schools

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• Washington Center School of Medicine

Doctors Specialties

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• Internal Medicine

Accepted Insurances

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