Associate Professor, Pediatrics, Washington University in St. Louis School of Medicine
Pediatric Infectious Disease
Dr. David B. Haslam, MD
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Dr. David B. Haslam practices Pediatric Infectious Disease. David Haslam is a published doctor. He has 28 papers published. The most current publication "Expression cloning of Forssman glycolipid synthetase: a novel member of the histo-blood group ABO gene family."
Publications
- Metagenomic Approach for Identification of the Pathogens Associated with Diarrhea in Stool Specimens.
- The molecular basis of Clostridium difficile disease and host response.
- Intestinal Inflammatory Biomarkers and Outcome in Pediatric Clostridium difficile Infections.
- Viral Co-infections are Common and are Associated with Higher Bacterial Burden in Children with C. difficile Infection.
- Markers of Intestinal Inflammation, not Bacterial Burden, Correlate with Clinical Outcomes in Clostridium difficile Infection.
- Structural and Functional Interactions between the Cholera Toxin A1 Subunit and ERdj3/HEDJ, a Chaperone of the Endoplasmic Reticulum.
- Golgicide A reveals essential roles for GBF1 in Golgi assembly and function.
- Contribution of the HEDJ/ERdj3 cysteine-rich domain to substrate interactions.
- Identification and characterization of small molecules that inhibit intracellular toxin transport.
- Shiga toxin is transported from the endoplasmic reticulum following interaction with the luminal chaperone HEDJ/ERdj3.
- Forssman synthetase expression results in diminished shiga toxin susceptibility: a role for glycolipids in determining host-microbe interactions.
- Managing the child with fever and neutropenia in an era of increasing microbial resistance.
- Bacterial adhesion and colonization assays.
- The PapG-adhesin at the tip of P-fimbriae provides Escherichia coli with a competitive edge in experimental bladder infections of cynomolgus monkeys.
- The Gal(alpha 1-4)Gal-specific tip adhesin of Escherichia coli P-fimbriae is needed for pyelonephritis to occur in the normal urinary tract.
- Molecular dissection of PapD interaction with PapG reveals two chaperone-binding sites.
- The amino-terminal domain of the P-pilus adhesin determines receptor specificity.
- Expression cloning of human globoside synthase cDNAs. Identification of beta 3Gal-T3 as UDP-N-acetylgalactosamine:globotriaosylceramide beta 1,3-N-acetylgalactosaminyl...
- HEDJ, an Hsp40 co-chaperone localized to the endoplasmic reticulum of human cells.
- Characterization of the human Forssman synthetase gene. An evolving association between glycolipid synthesis and host-microbial interactions.
- Expression cloning of Forssman glycolipid synthetase: a novel member of the histo-blood group ABO gene family.
- Disseminated measles infection after vaccination in a child with a congenital immunodeficiency.
- Prenatal identification of a deleted Y chromosome by cytogenetics and a Y-specific repetitive DNA probe.
- Improved direct molecular diagnosis and rapid fetal sexing.
- The ecology and pathobiology of Clostridium difficile infections: an interdisciplinary challenge.
- A quantitative and highly sensitive luciferase-based assay for bacterial toxins that inhibit protein synthesis.
- The MAP kinase-activated protein kinase 2 (MK2) contributes to the Shiga toxin-induced inflammatory response.
Schools
University of Calgary Faculty of Medicine
McGill University
Chldns Hospital E Ontario
St Louis Chldns Hospital
Doctors Specialties
- Pediatric Infectious Disease Medicine
- Pediatric Infectious Disease
Accepted Insurances
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