Professor and Chair of Neurology
Neurology
Dr. David G. Standaert, MD
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Dr. David G. Standaert works in the field of Neurology. He graduated from Washington University School of Medicine in St. Louis. He has 1 awards "Regional Top Doctor". David Standaert is a published MD. He published 100 publications, including: 'Treating Parkinson's disease.' Doctor David G. Standaert, MD accepts Medicare payments and is registered with Medicare.gov.
Publications
- microRNA-155 Regulates Alpha-Synuclein-Induced Inflammatory Responses in Models of Parkinson Disease.
- The Metabotropic Glutamate Receptor 4 Positive Allosteric Modulator ADX88178 Inhibits Inflammatory Responses in Primary Microglia.
- Environmental and Occupational Risk Factors for Progressive Supranuclear Palsy: Case-Control Study.
- Role of α-Synuclein in Inducing Innate and Adaptive Immunity in Parkinson Disease.
- Levodopa-carbidopa intestinal gel in advanced Parkinson's Disease: Final 12-month, open-label results.
- Monocytes and Parkinson's Disease: invaders from outside?
- Fiber-modified adenovirus for central nervous system Parkinson's Disease gene therapy.
- Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodents.
- A Full-Brain, Bootstrapped Analysis of Diffusion Tensor Imaging Robustly Differentiates Parkinson Disease from Healthy Controls.
- Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's Disease: a randomised, controlled, double-blind, double-du...
- Novel, high-intensity exercise prescription improves muscle mass, mitochondrial function, and physical capacity in individuals with Parkinson's Disease.
- Reaping what you sow: Cross-seeding between aggregation-prone proteins in neurodegeneration.
- Metabolomics and the search for biomarkers in Parkinson's Disease.
- Rotigotine polyoxazoline conjugate SER-214 provides robust and sustained antiparkinsonian benefit.
- LRRK2 Secretion in Exosomes is Regulated by 14-3-3.
- MHCII is required for alpha-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration.
- Removing the blinkers: moving beyond striatal dopamine in Parkinson's Disease.
- Levodopa-carbidopa intestinal gel in advanced Parkinson's Disease open-label study: Interim results.
- Angiogenin in Parkinson Disease Models: Role of Akt Phosphorylation and Evaluation of AAV-Mediated Angiogenin Expression in MPTP Treated Mice.
- The gamma chain subunit of Fc receptors is required for alpha-synuclein-induced pro-Inflammatory signaling in microglia.
- CD4+ Regulatory and Effector/Memory T Cell Subsets Profile Motor Dysfunction in Parkinson's Disease.
- Evaluation of TorsinA as a Target for Parkinson Disease Therapy in Mouse Models.
- Cholinergic Dysfunction Alters Synaptic Integration between Thalamostriatal and Corticostriatal Inputs in DYT1 Dystonia.
- Cholinergic dysregulation produced by selective inactivation of the Dystonia-associated protein torsinA.
- Alteration of striatal dopaminergic neurotransmission in a mouse model of DYT11 myoclonus-Dystonia.
- The Parkinson Progression Marker Initiative (PPMI).
- Unilateral subthalamic nucleus deep brain stimulation improves sleep quality in Parkinson's Disease.
- Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.
- Update on the pathology of Dystonia.
- Parkinson's Disease, primates, and gene therapy: vive la différence?
- Developmental Profile of the Aberrant Dopamine D2 Receptor Response in Striatal Cholinergic Interneurons in DYT1 Dystonia.
- Motor deficits and decreased striatal dopamine receptor 2 binding activity in the striatum-specific dyt1 conditional knockout mice.
- Altered Dendritic Morphology of Purkinje cells in Dyt1 ΔGAG Knock-In and Purkinje Cell-Specific Dyt1 Conditional Knockout Mice.
- Dopamine D2 receptor dysfunction is rescued by adenosine A2A receptor antagonism in a model of DYT1 Dystonia.
- VPS41, a protein involved in lysosomal trafficking, is protective in Caenorhabditis elegans and mammalian cellular models of Parkinson's Disease.
- Levodopa-induced dyskinesia is associated with increased thyrotropin releasing hormone in the dorsal striatum of hemi-parkinsonian rats.
- Transduction of Brain dopamine neurons by adenoviral vectors is modulated by CAR expression: rationale for tropism modified vectors in PD gene therapy.
- Impaired striatal D2 receptor function leads to enhanced GABA transmission in a mouse model of DYT1 Dystonia.
- Dysregulation of CalDAG-GEFI and CalDAG-GEFII predicts the severity of motor side-effects induced by anti-parkinsonian therapy.
- Investigating bacterial sources of Toxicity as an environmental contributor to dopaminergic neurodegeneration.
- Targeted overexpression of human alpha-synuclein triggers microglial activation and an adaptive immune response in a mouse model of Parkinson Disease.
- Transcriptional dysregulation in a transgenic model of Parkinson Disease.
- Biochemical fractionation of Brain tissue for studies of receptor distribution and trafficking.
- Design of clinical trials of gene therapy in Parkinson Disease.
- Angiotensin II protects against alpha-synuclein Toxicity and reduces protein aggregation in vitro.
- Pharmacological inhibition of PARP-1 reduces alpha-synuclein- and MPP+-induced cytotoxicity in Parkinson's Disease in vitro models.
- Effects of gender on nigral gene expression and parkinson Disease.
- Molecular markers of early Parkinson's Disease based on gene expression in blood.
- Dopamine D1 activation potentiates striatal NMDA receptors by tyrosine phosphorylation-dependent subunit trafficking.
- Alpha-synuclein and chaperones in Dementia with Lewy bodies.
- Somatic mitochondrial DNA mutations in single neurons and glia.
- Impaired motor learning in mice expressing torsinA with the DYT1 Dystonia mutation.
- Applications of laser capture microdissection in the study of neurodegenerative Disease.
- NMDA-R1 antisense oligodeoxynucleotides modify formalin-induced nociception and spinal c-Fos expression in rat spinal cord.
- L-type Ca2+ channels mediate adaptation of extracellular signal-regulated kinase 1/2 phosphorylation in the ventral tegmental area after Chronic amphetamine treatment.
- Changes in the expression of the NR2B subunit during aging in macaque monkeys.
- Dopamine D1-dependent trafficking of striatal N-methyl-D-aspartate glutamate receptors requires Fyn protein tyrosine kinase but not DARPP-32.
- Data mining techniques to detect motor fluctuations in Parkinson's Disease.
- Dopamine transmission in DYT1 Dystonia.
- Adenosine A2A receptor modulation of motor systems for symptomatic therapy in Parkinson's Disease.
- Complex alteration of NMDA receptors in transgenic Huntington's Disease mouse brain: analysis of mRNA and protein expression, plasma membrane association, interacting ...
- Lighting up the senses: FM1-43 loading of sensory cells through nonselective ion channels.
- Wearable technology's applications in Parkinson's Disease.
- TorsinA protein and neuropathology in early onset generalized Dystonia with GAG deletion.
- Identification of nitric oxide synthase neurons for laser capture microdissection and mRNA quantification.
- Inherited movement Disorders.
- Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's Disease.
- Immunohistochemical localization of metabotropic glutamate receptors mGluR1a and mGluR2/3 in the rat basal ganglia.
- Expression of N-methyl-D-aspartate receptor subunit mRNAs in the human Brain: striatum and globus pallidus.
- Expression of N-methyl-D-aspartate receptor subunit mRNAs in the human Brain: hippocampus and cortex.
- Expression of N-methyl-D-aspartate receptor subunit mRNA in the human Brain: mesencephalic dopaminergic neurons.
- NMDAR1 glutamate receptor subunit isoforms in neostriatal, neocortical, and hippocampal nitric oxide synthase neurons.
- Differential localization of the mRNAs for the pertussis toxin insensitive G-protein alpha sub-units Gq, G11, and Gz in the rat Brain, and regulation of their expressi...
- Expression of the early-onset torsion dystonia gene (DYT1) in human Brain.
- Expression of metabotropic glutamate receptor 1 isoforms in the substantia nigra pars compacta of the rat.
- Simultaneous isotopic and nonisotopic in situ hybridization histochemistry with cRNA probes.
- The human N-methyl-D-aspartate receptor 2C subunit: genomic analysis, distribution in human Brain, and functional expression.
- Pramipexole vs levodopa as initial treatment for Parkinson Disease: a 4-year randomized controlled trial.
- Using wearable sensors to predict the severity of symptoms and motor complications in late stage Parkinson's Disease.
- Monitoring motor fluctuations in patients with Parkinson's Disease using wearable sensors.
- Function of dopamine transporter is compromised in DYT1 transgenic animal model in vivo.
- Research goals in progressive supranuclear palsy. First International Brainstorming Conference on PSP.
- A(2A) adenosine receptor deficiency attenuates Brain injury induced by transient focal ischemia in mice.
- Treating Parkinson's Disease.
- Inhibition of endothelial cell regrowth. Cessation of aortic endothelial cell replication after balloon catheter denudation.
- Cloning and stable expression of the mGluR1b subtype of human metabotropic receptors and pharmacological comparison with the mGluR5a subtype.
- A neuroprotective role for angiogenin in models of Parkinson''s Disease.
- Differential neuroprotective effects of 14-3-3 proteins in models of Parkinson''s Disease.
- Fcγ receptors are required for NF-κB signaling, microglial activation and dopaminergic neurodegeneration in an AAV-synuclein mouse model of Parkinson's Disease.
- Target validation: the Parkinson Disease perspective.
- Racial differences in Parkinson''s Disease medication use in the reasons for geographic and racial differences in stroke cohort: a cross-sectional study.
- Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 Dystonia: role of endogenous acetylcholine.
- Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and Toxicity.
- Targets for neuroprotection in Parkinson''s Disease.
- The pathophysiological basis of Dystonias.
- Differential synaptic plasticity of the corticostriatal and thalamostriatal Systems in an MPTP-treated monkey model of parkinsonism.
- Striatal histone modifications in models of levodopa-induced dyskinesia.
- Dopamine release is impaired in a mouse model of DYT1 Dystonia.
- Dopaminergic neuron loss and up-regulation of chaperone protein mRNA induced by targeted over-expression of alpha-synuclein in mouse substantia nigra.
Schools
Washington Center School of Medicine
Procedures Preformed
- EEG (Electroencephalogram)
- EMG (Electromyography)
Conditions Treated
- Alzheimer's Disease
- Anterior Horn Disease
- Ataxia
- Autonomic Disorders
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Doctors Specialties
- Neurology
Accepted Insurances
Awards
- Regional Top Doctor
Education
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Massachusetts General Hospital -
University of Pennsylvania Health System -
Washington University - Barnes-Jewish Hospital -
Washington University School of Medicine in St. Louis
Hospital
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University of Alabama Hospital
Drug Facts
| NPI NUMBER | 1588654495 | |
| NPPES Provider LastName | STANDAERT | |
| NPPES Provider FirstName | DAVID | |
| NPPES Provider ZIPCode | 352555309 | |
| NPPES Provider State | AL | |
| Specialty Description | Neurology | |
| Total Claim Count | 1010.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1588654495 |
| Last Name Of The Provider | STANDAERT |
| First Name Of The Provider | DAVID |
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