Professor of Clinical Genetics, University Colorado
Medical Genetics
Dr. David K. Manchester, MD
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Dr. David K. Manchester practices Medical Genetics. He graduated from University of California San Francisco School of Medicine. University of California San Francisco School of Medicine is one of the top medical schools in the US. University of California San Francisco School of Medicine is ranked 3/3 in Research/PrimaryCare. David K. Manchester, MD is also published. He has 81 publications published. The lastest publication: "Human placental microsomal activation and DNA adduction by air pollutants.'
Publications
- Benzo(a)pyrene inhibits epidermal growth factor binding and receptor autophosphorylation in human placental cell cultures.
- Visual, vestibular and somatosensory contributions to balance control in the older adult.
- Apparent Smith-Lemli-Opitz syndrome and Miller-Dieker syndrome in a family with segregating translocation t(7;17)(q34;p13.1).
- Fetal omphalocele and gastroschisis: a review of 24 cases.
- Doppler ultrasound of twin transfusion syndrome.
- Possible association between maternal indomethacin therapy and primary pulmonary hypertension of the newborn.
- Pathologic aspects of fetal death.
- Specific skeletal dysplasias in utero: sonographic diagnosis.
- The application of immunoassays and fluorometry to the detection of polycyclic hydrocarbon-macromolecular adducts and anti-adduct antibodies in humans.
- Response preparation and posture control. Neuromuscular changes in the older adult.
- The clinical significance of increased echogenicity in the fetal abdomen.
- Clinical course of fetal hydrocephalus: 40 cases.
- Sensory-vocal studies of a twin pair with cephalic union.
- Echocardiographic diagnosis and intravenous digoxin management of fetal tachyarrhythmias and congestive heart failure.
- Decreased placental monooxygenase activities associated with birth defects.
- Fetal hydrocephalus: diagnosis and management.
- DNA adduct profiles and levels in placenta, blood and lung in relation to cigarette smoking and smoky coal emissions.
- Neuroleptics, learning disability, and the community: some history and mystery.
- A non-aversive approach to reducing hospital absconding in a head-injured adolescent boy.
- Mutations in the delta-sarcoglycan gene are a rare cause of autosomal recessive limb-girdle muscular dystrophy (LGMD2).
- PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome.
- Fragile X syndrome and an isodicentric X chromosome in a woman with multiple anomalies, developmental delay, and normal pubertal development.
- Promoting cancer screening among the first-degree relatives of breast and colorectal cancer patients: the design of two randomized trials.
- Recent developments in molecular epidemiology: A study of the effects of environmental polycyclic aromatic hydrocarbons on birth outcomes in Poland.
- Meiotic segregation, recombination, and gamete aneuploidy assessed in a t(1;10)(p22.1;q22.3) reciprocal translocation carrier by three- and four-probe multicolor FISH ...
- Prolonged, severe behavioural disturbance following traumatic brain injury: what can be done?
- A serological marker for neonatal lupus erythematosus.
- Towards the development of brain injury specialists.
- Importance of the clinical recognition of Loeys-Dietz syndrome in the neonatal period.
- A forensic peer group approach to bullying after traumatic brain injury.
- Two approaches to behavior disorder after traumatic brain injury.
- Deletions flanked by breakpoints 3 and 4 on 15q13 may contribute to abnormal phenotypes.
- The assessment of executive functions: coming out of the office.
- Ethnic variability in the allelic distribution of human aryl hydrocarbon receptor codon 554 and assessment of variant receptor function in vitro.
- The perinatal autopsy: special considerations.
- Fetal heart rate in relation to body mass.
- Binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin to AH receptor in placentas from normal versus abnormal pregnancy outcomes.
- Human placental microsomal activation and DNA adduction by air pollutants.
- Polycyclic aromatic hydrocarbon-DNA adducts in human placenta and modulation by CYP1A1 induction and genotype.
- Human doublecortin (DCX) and the homologous gene in mouse encode a putative Ca2+-dependent signaling protein which is mutated in human X-linked neuronal migration defe...
- Relationship between ambient air pollution and DNA damage in Polish mothers and newborns.
- Hunter-McAlpine craniosynostosis phenotype associated with skeletal anomalies and interstitial deletion of chromosome 17q.
- Detection of polycyclic aromatic hydrocarbon-DNA adducts in human lung.
- Parental somatic and germ-line mosaicism for a multiexon deletion with unusual endpoints in a type III collagen (COL3A1) allele produces Ehlers-Danlos syndrome type IV...
- Sensitivity of somatic mutations in human umbilical cord blood to maternal environments.
- Sensitivity of human placental monooxygenase activity to maternal smoking.
- Glutathione S-transferase activities in placentas from smoking and non-smoking women.
- Resolution and reconstitution of human placental monooxygenase activity responsive to maternal cigarette smoking.
- Recurrent maternal floor infarction: a preventable cause of fetal death.
- Monoclonal antibody phenotyping of interindividual differences in cytochrome P-450-dependent reactions of single and twin human placenta.
- Maternal smoking increases xenobiotic metabolism in placenta but not umbilical vein endothelium.
- An outbreak of rotavirus-associated neonatal necrotizing enterocolitis.
- Range of environmentally responsive monooxygenase activities in human placental microsomes determined by direct fluorescence techniques.
- Perinatal autopsy: its clinical value.
- Two massive congenital intracranial immature teratomas with neck extension.
- Ventriculomegaly: evaluation and management.
- Dosage of phenytoin during pregnancy.
- Diagnosis and management of fetal hydrocephalus.
- High resolution proton NMR spectroscopy of human amniotic fluid.
- Severe polyhydramnios: incidence of anomalies.
- Lymphedema in Noonan syndrome: clues to pathogenesis and prenatal diagnosis and review of the literature.
- Tracheoesophageal fistula in utero. Twenty-two cases.
- Accuracy of ultrasound diagnoses in pregnancies complicated by suspected fetal anomalies.
- The effect of birth on the maturation of hepatic cytochrome(s) P-450 mono-oxygenase and tyrosine aminotransferase activities in the guinea pig.
- Dosimeters of human exposure to carcinogens: polycyclic aromatic hydrocarbon-macromolecular adducts.
- Detection of benzo[a]pyrene diol epoxide-DNA adducts in human placenta.
- Ah receptor in human placenta: stabilization by molybdate and characterization of binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin, 3-methylcholanthrene, and benzo(a)pyr...
- Fluorescence and mass spectral evidence for the formation of benzo[a]pyrene anti-diol-epoxide-DNA and -hemoglobin adducts in humans.
- Twin study methodology and variability in xenobiotic placental metabolism.
- Alkyl and aryl carcinogen adducts detected in human peripheral lung.
- Derivative fluorescence spectral analysis of polycyclic aromatic hydrocarbon-DNA adducts in human placenta.
- Synchronous fluorescence spectroscopic, immunoaffinity chromatographic and 32P-postlabeling analysis of human placental DNA known to contain benzo[a]pyrene diol epoxid...
- Competitive binding of 7-substituted-2,3-dichlorodibenzo-p-dioxins with human placental ah receptor--a QSAR analysis.
- Fluorescence detection of lesions in DNA.
- Determinants of polycyclic aromatic hydrocarbon-DNA adducts in human placenta.
- X-linked myotubular myopathy: a case report of prenatal and perinatal aspects.
- Modeling of lung morphogenesis using fractal geometries.
- Use of the Internet by patients and their families to obtain genetics-related information.
- Assessment of multiple types of DNA damage in human placentas from smoking and nonsmoking women in the Czech Republic.
- Molecular and clinical analyses of Greig cephalopolysyndactyly and Pallister-Hall syndromes: robust phenotype prediction from the type and position of GLI3 mutations.
Schools
University Of California San Francisco School Of Medicine
University Of Colorado University Hospital Program
Doctors Specialties
- Clinical Genetics
- Pediatrics
- Medical Genetics
Accepted Insurances
Education
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University of Colorado -
University of California San Francisco School of Medicine
Hospital
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University of Colorado Hospital -
Children's Hospital Colorado
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1750708475 |
| Last Name Of The Provider | MANCHESTER |
| First Name Of The Provider | DAVID |
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