Professor, Medicine, Oregon Health and Science University School of Medicine
Pulmonology
Dr. David M. Lewinsohn, MD
David Lewinsohn practices Pulmonology. He studied medicine at Stanford University School of Medicine. Stanford University School of Medicine is a one of the best medicals schools. Stanford University School of Medicine has a rank of 2 in research and a 25 in primary care David Lewinsohn is a published doctor and has 78 publications published. The lastest was: 'Characterization of human CD8+ T cells reactive with Mycobacterium tuberculosis-infected antigen-presenting cells.'
Publications
- MR1-restricted mucosal associated invariant T (MAIT) cells in the immune response to Mycobacterium tuberculosis.
- High expression of CD26 accurately identifies human bacteria-reactive MR1-restricted MAIT cells.
- ATS Core Curriculum 2014: part I. Adult pulmonary medicine.
- Antigens for CD4 and CD8 T Cells in Tuberculosis.
- T cell inactivation by poxviral b22 family proteins increases viral virulence.
- Lipoproteins are major targets of the polyclonal human T cell response to Mycobacterium tuberculosis.
- Co-dependents: MR1-restricted MAIT cells and their antimicrobial function.
- Human thymic MR1-restricted MAIT cells are innate pathogen-reactive effectors that adapt following thymic egress.
- CD8+ T cells provide an immunologic signature of tuberculosis in young children.
- Vitamin D Is Required for IFN-{gamma}-Mediated Antimicrobial Activity of Human Macrophages.
- Mucosal associated invariant T cells and the immune response to infection.
- Secreted immunodominant Mycobacterium tuberculosis antigens are processed by the cytosolic pathway.
- Human mucosal associated invariant T cells detect bacterially infected cells.
- New diagnostic methods for tuberculosis.
- The Mycobacterium tuberculosis phagosome is a HLA-I processing competent organelle.
- A-kinase anchoring in dendritic cells is required for antigen presentation.
- T-cell epitope mapping in Mycobacterium tuberculosis using pepmixes created by micro-scale SPOT- synthesis.
- Interferon-gamma release assays for diagnosing mycobacterium tuberculosis infection in renal dialysis patients.
- Profiling antibodies to Mycobacterium tuberculosis by multiplex microbead suspension arrays for serodiagnosis of tuberculosis.
- Human innate Mycobacterium tuberculosis-reactive alphabetaTCR+ thymocytes.
- Immunologic susceptibility of young children to Mycobacterium tuberculosis.
- Immunodominant tuberculosis CD8 antigens preferentially restricted by HLA-B.
- Human neonatal dendritic cells are competent in MHC class I antigen processing and presentation.
- Differential antigenic hierarchy associated with spontaneous recovery from hepatitis C virus infection: implications for vaccine design.
- Secreted proteins from Mycobacterium tuberculosis gain access to the cytosolic MHC class-I antigen-processing pathway.
- Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4+ CTL.
- Interferon-gamma assays for tuberculosis: is anergy the Achilles' heel?
- Immune evasion versus recovery after acute hepatitis C virus infection from a shared source.
- Reconstitution of hepatitis C virus-specific T-cellmediated immunity after liver transplantation.
- Cutting edge: identification of hepatitis C virus-specific CD8+ T cells restricted by donor HLA alleles following liver transplantation.
- Identification of a human HLA-E-restricted CD8+ T cell subset in volunteers immunized with Salmonella enterica serovar Typhi strain Ty21a typhoid vaccine.
- Characterization of a Mycobacterium tuberculosis peptide that is recognized by human CD4+ and CD8+ T cells in the context of multiple HLA alleles.
- Use of a clinical pathway to manage unsuspected radiographic findings.
- Mycobacterium tuberculosis-specific CD8+ T cells preferentially recognize heavily infected cells.
- TB vaccines at the turn of the century: insights into immunity to M. tuberculosis and modern approaches for prevention of an ancient disease.
- Novel CD4+ and CD8+ T-cell determinants within the NS3 protein in subjects with spontaneously resolved HCV infection.
- HLA-E-dependent presentation of Mtb-derived antigen to human CD8+ T cells.
- Inhibition of HLA-DR assembly, transport, and loading by human cytomegalovirus glycoprotein US3: a novel mechanism for evading major histocompatibility complex class I...
- Human dendritic cells presenting adenovirally expressed antigen elicit Mycobacterium tuberculosis--specific CD8+ T cells.
- Infection of APC by human cytomegalovirus controlled through recognition of endogenous nuclear immediate early protein 1 by specific CD4(+) T lymphocytes.
- HIV-1 Vpr does not inhibit CTL-mediated apoptosis of HIV-1 infected cells.
- Frequencies of HCV-specific effector CD4+ T cells by flow cytometry: correlation with clinical disease stages.
- Human Lung Epithelial Cells Contain Mycobacterium tuberculosis in a Late Endosomal Vacuole and Are Efficiently Recognized by CD8+ T Cells.
- Mycobacterium tuberculosis Specific CD8(+) T Cells Rapidly Decline with Antituberculosis Treatment.
- TAP Mediates Import of Mycobacterium tuberculosis-Derived Peptides into Phagosomes and Facilitates Loading onto HLA-I.
- Human Mycobacterium tuberculosis CD8 T Cell Antigens/Epitopes Identified by a Proteomic Peptide Library.
- Lymphocyte migration molecules.
- Application of T cell immunotherapy for human viral and malignant diseases.
- Immunotherapy of human viral and malignant diseases with genetically modified T-cell clones.
- Stereological analysis of bacterial load and lung lesions in nonhuman primates (rhesus macaques) experimentally infected with Mycobacterium tuberculosis.
- Interactions between endothelial cells and leukocytes.
- Mycobacterium tuberculosis-reactive CD8+ T lymphocytes: the relative contribution of classical versus nonclassical HLA restriction.
- A fluorometric approach to the quantitation of cell number with application to a cell adhesion assay.
- Recombinant gamma interferon increases the binding of peripheral blood mononuclear leukocytes and a Leu-3+ T lymphocyte clone to cultured keratinocytes and to a malign...
- Enhanced binding of peripheral blood mononuclear leukocytes to gamma-interferon-treated cultured keratinocytes.
- Use of polymerase chain reaction for successful identification of asymptomatic genital infection with herpes simplex virus in pregnant women at delivery.
- Hematopoietic progenitor cell expression of the H-CAM (CD44) homing-associated adhesion molecule.
- Expression cloning of an immunodominant family of Mycobacterium tuberculosis antigens using human CD4(+) T cells.
- Cytomegalovirus US2 destroys two components of the MHC class II pathway, preventing recognition by CD4+ T cells.
- Molecular characterization and human T-cell responses to a member of a novel Mycobacterium tuberculosis mtb39 gene family.
- Characterization of human CD8+ T cells reactive with Mycobacterium tuberculosis-infected antigen-presenting cells.
- Human purified protein derivative-specific CD4+ T cells use both CD95-dependent and CD95-independent cytolytic mechanisms.
- CD40 ligand inhibits Fas/CD95-mediated apoptosis of human blood-derived dendritic cells.
- Phase I study of intravenous ribavirin treatment of respiratory syncytial virus pneumonia after marrow transplantation.
- Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes.
- Rudimentary TCR signaling triggers default IL-10 secretion by human Th1 cells.
- T-cell clones derived by CD3 stimulation from hepatitis C virus explanted liver tissue are not representative of dominant clones present in vivo.
- Classically restricted human CD8+ T lymphocytes derived from Mycobacterium tuberculosis-infected cells: definition of antigenic specificity.
- Tuberculosis immunology in children: diagnostic and therapeutic challenges and opportunities.
- Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis.
- Role of CD8+ T lymphocytes in control of Mycobacterium tuberculosis infection.
- Alterations in T-cell subset frequency in peripheral blood in obesity.
- High resolution radiographic and fine immunologic definition of TB disease progression in the rhesus macaque.
- Meeting Report: NIH Workshop on the Tuberculosis Immune Epitope Database.
- Views of immunology: effector T cells.
- Identification of MHC class II restricted T-cell-mediated reactivity against MHC class I binding Mycobacterium tuberculosis peptides.
- An analysis of the epitope knowledge related to Mycobacteria.
Schools
Stanford University
University of Washington
Conditions Treated
- Sarcoidosis
- Sleep Apnea
Doctors Specialties
- Critical Care Medicine
- Pulmonology
Accepted Insurances
- Assurant Health
- Blue Card PPO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- Open Access Plus
- Commercial Insurance Company
- First Choice Health PPO
- First Health (Coventry Health Care) PPO
- GEHA
- Health Plan of Oregon PPO
- Medicare MCR
- ODS Health Plan
- Preferred PSN
- Heritage Plus
- Heritage Signature
- Preferred PPO
- Choice Plus POS
- Options PPO
- United Healthcare
Education
-
University of Washington -
UCSF -
Stanford University School of Medicine
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