Physician
Endocrinology
Dr. David S. Weigle, MD
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David S. Weigle is an expert in the field of Endocrinology. He researched medicine at Harvard Medical School. Harvard Medical School is a top medical university. Harvard Medical School has a rank of 1 in research and a 12 in primary care He over the years received 2 awards: "Regional Top Doctor" and "Fellow (FACP)". Dr. David S. Weigle is also a published doctor. He has 72 paper published. The most recent paper is: Effects of energy intake on the regulation of plasma leptin concentrations.
Publications
- Adrenal Insufficiency as a Result of Ritonavir and Exogenous Steroid Exposure: Report of 6 Cases and Recommendation for Management.
- Effects of a High-Protein Diet on Regulation of Phosphorus Homeostasis.
- Frequent intentional weight loss is associated With higher ghrelin and lower glucose and androgen levels in postmenopausal women.
- Hypercaloric diets differing in fat composition have similar effects on serum leptin and weight gain in female subjects With anorexia nervosa.
- Energy balance in congenital generalized lipodystrophy Type I.
- Peripheral ghrelin treatment stabilizes body weights of senescent male Brown Norway rats at baseline and after surgery.
- The Obesity epidemic: pharmacological challenges.
- Reduced adipogenic gene expression in thigh adipose tissue precedes human immunodeficiency virus-associated lipoatrophy.
- Effect of dietary n-3 polyunsaturated fatty acids on plasma total and high-molecular-weight adiponectin concentrations in overweight to moderately obese men and women.
- Adaptation to altitude as a vehicle for experiential learning of physiology by university undergraduates.
- Plasma C-reactive protein concentration is not affected by isocaloric dietary fat reduction.
- Effect of aging on the response of ghrelin to acute weight loss.
- A high-protein diet induces sustained reductions in appetite, ad libitum caloric intake, and body weight despite compensatory changes in diurnal plasma leptin and ghre...
- Insulin, C-peptide, and leptin concentrations predict increased visceral adiposity at 5- and 10-year follow-ups in nonDiabetic Japanese Americans.
- Effects of exercise on metabolic risk variables in overweight postmenopausal women: a randomized clinical trial.
- Postprandial suppression of plasma ghrelin level is proportional to ingested caloric load but does not predict intermeal interval in humans.
- Ghrelin levels correlate With insulin levels, insulin resistance, and high-density lipoprotein cholesterol, but not With gender, menopausal status, or cortisol levels ...
- Circulating ghrelin levels are suppressed by meals and octreotide therapy in children With Prader-Willi syndrome.
- Pharmacological therapy of Obesity: past, present, and future.
- Roles of leptin and ghrelin in the loss of body weight caused by a low fat, high carbohydrate diet.
- Absence of hypersensitivity to glucocorticoids in antiretroviral-associated lipodystrophy.
- Leptin levels are appropriate for body mass index in older men who experience involuntary weight loss.
- Elevated plasma ghrelin levels in Prader Willi syndrome.
- Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery.
- Serum leptin concentrations and markers of immune function in overweight or obese postmenopausal women.
- Exchanging carbohydrate or protein for fat improves Lipid-related cardiovascular risk profile in overweight men and women when consumed ad libitum.
- Dietary n-3-polyunsaturated fatty acids and energy balance in overweight or moderately obese men and women: a randomized controlled trial.
- Serum steroid hormones, sex hormone-binding globulin concentrations, and urinary hydroxylated estrogen metabolites in post-menopausal women in relation to daidzein-met...
- Evaluation of leptin levels in subjects at risk for type 1 Diabetes.
- Modified macronutrient diets and weight loss--are food choice and variety more important than caloric restriction?
- Changes in plasma amino Acid levels do not predict satiety and weight loss on diets With modified macronutrient composition.
- A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans.
- Defective dietary induction of uncoupling protein 3 in skeletal muscle of Obesity-prone rats.
- Effects of streptozotocin-induced Diabetes and insulin treatment on the hypothalamic melanocortin system and muscle uncoupling protein 3 expression in rats.
- Association between baseline plasma leptin levels and subsequent development of Diabetes in Japanese Americans.
- Effects of energy intake on the regulation of plasma leptin concentrations.
- Leptin does not fully account for the satiety activity of adipose tissue-conditioned medium.
- Increased expression of mRNA for the long form of the leptin receptor in the hypothalamus is associated With leptin hypersensitivity and fasting.
- Elevated free fatty acids induce uncoupling protein 3 expression in muscle: a potential explanation for the effect of fasting.
- Increased plasma leptin levels are associated With fat accumulation in Japanese Americans.
- Synergy between leptin and cholecystokinin (CCK) to control daily caloric intake.
- Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus.
- Leptin and other secretory products of adipocytes modulate multiple physiological functions.
- Recombinant leptin exchanges between parabiosed mice but does not reach equilibrium.
- Effect of regional fat distribution and Prader-Willi syndrome on plasma leptin levels.
- Effect of fasting, refeeding, and dietary fat restriction on plasma leptin levels.
- Leptin is a metabolic gate for the onset of puberty in the female rat.
- Obesity genes and the regulation of body fat content.
- Leptin is a metabolic signal to the reproductive system.
- Frequency of Thyroid disease among Southeast Asian primary care patients.
- Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice.
- Appetite and the regulation of body composition.
- Accelerated cholesteryl ester transfer in baboons with insulin-requiring Diabetes mellitus.
- Recombinant ob protein reduces feeding and body weight in the ob/ob mouse.
- Pulsatile glucagon delivery enhances glucose production by perifused rat hepatocytes.
- A model for augmentation of hepatocyte response to pulsatile glucagon stimuli.
- Evidence that the physiological pulse frequency of glucagon secretion optimizes glucose production by perifused rat hepatocytes.
- Pulsatile secretion of fuel-regulatory hormones.
- Contribution of decreased body mass to diminished thermic effect of exercise in reduced-obese men.
- Weight loss leads to a marked decrease in nonresting energy expenditure in ambulatory human subjects.
- Preliminary assessment of very low calorie diets by conventional and signal-averaged electrocardiography.
- Decreased insulin- and glucagon-pulse amplitude accompanying beta-cell deficiency induced by streptozocin in baboons.
- A kinetic analysis of hepatocyte responses to a glucagon pulse: mechanism and metabolic consequences of differences in response decay times.
- Identification of candidate genes for a factor regulating body weight in primates.
- Human Obesity. Exploding the myths.
- Assessment of energy expenditure in ambulatory reduced-obese subjects by the techniques of weight stabilization and exogenous weight replacement.
- Lack of evidence for improvement in long-term glycemic control by pulsatile insulin infusion in streptozocin-induced Diabetic baboon.
- Sleep, ghrelin, leptin and changes in body weight during a 1-year moderate-intensity physical activity intervention.
- Changes in 24-h area-under-the-curve ghrelin values following diet-induced weight loss are associated With loss of fat-free mass, but not With changes in fat mass, ins...
- Leptin levels recover normally in healthy older adults after acute diet-induced weight loss.
- Circulating TNF alpha receptor levels identify older adults who fail to regain weight after acute weight loss.
Schools
HARVARD MED SCH
University Chicago Hosps and Clins
University of Washington
Conditions Treated
- Abnormal Thyroid
- Adrenal Insufficiency
- Calcium Metabolism Disorders
- Craniopharyngioma
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Doctors Specialties
- Endocrinology
Accepted Insurances
- Blue Card PPO
- Cigna HMO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- Open Access Plus
- First Choice Health PPO
- ODS Health Plan
- Personal Option EPO
- Preferred Provider Network PPN
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
Awards
- Regional Top Doctor
- Fellow (FACP)
Education
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University of Washington -
University of Chicago -
Harvard Medical School
Hospital
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UW Medicine/Harborview Medical Center -
University of Washington Medical Center
Drug Facts
| NPI NUMBER | 1972632107 | |
| NPPES Provider LastName | WEIGLE | |
| NPPES Provider FirstName | DAVID | |
| NPPES Provider ZIPCode | 981042420 | |
| NPPES Provider State | WA | |
| Specialty Description | Endocrinology | |
| Total Claim Count | 216.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1972632107 |
| Last Name Of The Provider | WEIGLE |
| First Name Of The Provider | DAVID |
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