Professor, Internal Medicine, University of Utah School of Medicine
Cardiology
Dr. Dean Y. Li, MD
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Dr. Dean Y. Li practices Cardiology. He studied medicine at Washington University School of Medicine in St. Louis. He received awards:"Regional Top Doctor" and "Elected Member". Doctor Dean Y. Li, MD is a published doctor as well. He has 90 publications published. The latest was: Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts.
Publications
- Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed Hearts.
- Peripheral plasma vitamin D and non-HDL cholesterol reflect the severity of cerebral cavernous malformation Disease.
- Alternative preprocessing of RNA-Sequencing data in The Cancer Genome Atlas leads to improved analysis results.
- The cerebral cavernous malformation pathway controls cardiac development via regulation of endocardial MEKK3 signaling and KLF expression.
- Greater impairments in cerebral Artery compared with skeletal muscle feed Artery endothelial function in a mouse model of increased large Artery stiffness.
- Strategy for Identifying Repurposed Drugs for the Treatment of Cerebral Cavernous Malformation.
- Myocardial atrophy and chronic mechanical unloading of the failing human Heart: implications for cardiac assist device-induced myocardial recovery.
- Characterization of diffuse fibrosis in the failing human Heart via diffusion tensor imaging and quantitative histological validation.
- ARF6 Inhibition Stabilizes the Vasculature and Enhances Survival during Endotoxic Shock.
- UNC5B receptor deletion exacerbates DSS-induced colitis in mice by increasing epithelial cell apoptosis.
- Smooth muscle specific disruption of the endothelin-A receptor in mice reduces arterial pressure, and vascular reactivity and affects vascular development.
- Maintaining the Plexus: SYNJ2BP as a Novel Regulator of Angiogenesis.
- UNC5B Receptor Deletion Exacerbates Tissue Injury in Response to AKI.
- Activation of Rap1 inhibits NADPH oxidase-dependent ROS generation in retinal pigment epithelium and reduces choroidal neovascularization.
- Reply to Letter to the Editor: Left ventricular assist devices in chronic Heart failure: more questions than answers?
- Autophagy is a key feature in the pathogenesis of systemic sclerosis.
- Gas chromatography-mass spectrometry method for rapid identification and differentiation of Burkholderia pseudomallei and Burkholderia mallei from each other, Burkhold...
- Cationic dirhodium carboxylate-catalyzed synthesis of dihydropyrimidones from propargyl ureas.
- The Small GTPase ARF6 Stimulates ?-Catenin Transcriptional Activity During WNT5A-Mediated Melanoma Invasion and Metastasis.
- Magnitude and Time Course of Changes Induced by Continuous-Flow Left Ventricular Assist Device Unloading in Chronic Heart Failure: Insights into Cardiac Recovery.
- Pulsatility and the Risk of Non-Surgical Bleeding in Patients Supported With the Continuous-Flow Left Ventricular Assist Device HeartMate II.
- Morbidity and mortality in Heart transplant candidates supported with mechanical circulatory support: is reappraisal of the current United network for organ sharing th...
- Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability.
- Arteriovenous Malformations and Other Vascular Malformation Syndromes.
- Netrin Ligands and Receptors: Lessons From Neurons to the Endothelium.
- Bridge to recovery: understanding the disconnect between clinical and biological outcomes.
- Cationic PAMAM Dendrimers Disrupt Key Platelet Functions.
- Vascular Leak Is a Central Feature in the Pathogenesis of Systemic Sclerosis.
- Ventricular assist devices: Pharmacological aspects of a mechanical therapy.
- ABCB6 Mutations Cause Ocular Coloboma.
- Slit2/Robo4 Signaling Modulates HIV-1 gp120-Induced Lymphatic Hyperpermeability.
- Altered bladder function in elastin-deficient mice at baseline and in response to partial bladder outlet obstruction.
- Netrin-4 Activates Endothelial Integrin {alpha}6{beta}1.
- A luminescent oxygen channeling biosensor that measures small GTPase activation.
- Hadp1, a newly identified pleckstrin homology domain protein, is required for cardiac contractility in zebrafish.
- Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice.
- Left ventricular assist device unloading effects on myocardial structure and function: current status of the field and call for action.
- Robo4-dependent Slit signaling stabilizes the vasculature during pathologic angiogenesis and cytokine storm.
- Inhibition of transforming growth factor β worsens elastin degradation in a murine model of Kawasaki Disease.
- Novel approach for endothelializing vascular devices: understanding and exploiting elastin-endothelial interactions.
- Evaluating strategies for the treatment of cerebral cavernous malformations.
- Elastin haploinsufficiency results in progressive Aortic valve malformation and latent valve disease in a mouse model.
- Impact of mechanical unloading on microvasculature and associated central remodeling features of the failing human Heart.
- Netrin-4 induces lymphangiogenesis in vivo.
- Vascular Robo4 restricts proangiogenic VEGF signaling in breast.
- Mechanisms of vascular stability and the relationship to human Disease.
- Risk factors predictive of right ventricular Failure after left ventricular assist device implantation.
- Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza.
- Genetic and functional dissection of HTRA1 and LOC387715 in age-related macular degeneration.
- Slit-robo signaling in ocular angiogenesis.
- Prior human leukocyte antigen-allosensitization and left ventricular assist device type affect degree of post-implantation human leukocyte antigen-allosensitization.
- Distinct function of 2 chromatin remodeling complexes that share a common subunit, Williams syndrome transcription factor (WSTF).
- The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases.
- Roundabout 4 is expressed on hematopoietic stem cells and potentially involved in the niche-mediated regulation of the side population phenotype.
- HOXA13 Is essential for placental vascular patterning and labyrinth endothelial specification.
- Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.
- Elastin haploinsufficiency induces alternative aging processes in the aorta.
- Elastin-insufficient mice show normal cardiovascular remodeling in 2K1C Hypertension despite higher baseline pressure and unique cardiovascular architecture.
- Netrins promote developmental and therapeutic angiogenesis.
- Identification of new netrin family members in zebrafish: developmental expression of netrin 2 and netrin 4.
- Effects of elastin haploinsufficiency on the mechanical behavior of mouse arteries.
- roundabout4 is essential for angiogenesis in vivo.
- Altered vascular remodeling in fibulin-5-deficient mice reveals a role of fibulin-5 in smooth muscle cell proliferation and migration.
- The axonal attractant Netrin-1 is an angiogenic factor.
- Wiring the vascular circuitry: from growth factors to guidance cues.
- Developmental adaptation of the mouse cardiovascular system to elastin haploinsufficiency.
- Robo4 is a vascular-specific receptor that inhibits endothelial migration.
- Loss of distinct arterial and venous boundaries in mice lacking endoglin, a vascular-specific TGFbeta coreceptor.
- New insights into elastin and vascular Disease.
- The prospective role of transesophageal echocardiography in the diagnosis and management of patients with suspected infective endocarditis.
- Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity.
- Recent insights into cerebral cavernous malformations: animal models of CCM and the human phenotype.
- Novel polymer carriers and gene constructs for treatment of myocardial ischemia and infarction.
- Promoter polymorphism of the erythropoietin gene in severe diabetic eye and Kidney complications.
- The netrin receptor UNC5B promotes angiogenesis in specific vascular beds.
- Common cues regulate neural and vascular patterning.
- Domains 16 and 17 of tropoelastin in elastic fibre formation.
- A critical role for elastin signaling in vascular morphogenesis and Disease.
- Extracellular matrix in vascular morphogenesis and Disease: structure versus signal.
- Elastin induces myofibrillogenesis via a specific domain, VGVAPG.
- Ccm1 is required for arterial morphogenesis: implications for the etiology of human cavernous malformations.
- Genetic variants at 13q12.12 are associated with high myopia in the Han Chinese population.
- Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice.
- Robo4 cooperates with CXCR4 to specify hematopoietic stem cell localization to bone marrow niches.
- Characterization of erectile function in elastin haploinsufficicent mice.
- Augmented humoral and cellular immune responses to hepatitis B DNA vaccine adsorbed onto cationic microparticles.
- Motoneurons are essential for vascular pathfinding.
- Endogenous endothelial cell signaling systems maintain vascular stability.
- Assessing changes in vascular permeability in a hamster model of viral hemorrhagic fever.
Schools
Washington University In St Louis School Of Medicine
Barnes Jewish Hospital S Campus
Conditions Treated
- Aortic Valve Disease
- Arrhythmias (incl. Atrial Fibrillation)
- Congestive Heart Failure
- Coronary Artery Disease (CAD)
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Doctors Specialties
- Cardiology
Accepted Insurances
Awards
- Regional Top Doctor
- Elected Member
Education
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Washington University - Barnes-Jewish Hospital -
Washington University School of Medicine in St. Louis
Hospital
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University of Utah Health Care - Hospital and Clinics
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