Professor of Orthopedic Surgery, University Minn
Orthopaedic Surgery
Dr. Denis R. Clohisy, MD
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Denis R. Clohisy, MD is an expert in the field of Orthopaedic Surgery. He researched medicine at Northwestern University Feinberg School of Medicine. Northwestern University Feinberg School of Medicine is ranked 19 in research and 29 in primary care medicine He over the years received 5 awards: "America's Top Doctors", "America's Top Doctors for Cancer", "CMS Meaningful Use Stage 1 Certification", "Top MD" and "Super Doctor". Denis Clohisy has written publications. He has 64 publications published with PubMed. The lastest paper is: 'Osteoclasts are required for bone tumors to grow and destroy bone.' Doctor Denis R. Clohisy, MD is registered with Medicare.
Publications
- Management of Unplanned Excision for Soft-Tissue Sarcoma With Preoperative Radiotherapy Followed by Definitive Resection.
- Pilot study of vascular health in survivors of osteosarcoma.
- Chemotherapy Influences the Pseudocapsule Composition in Soft Tissue Sarcomas.
- Lentivirus transduction of human osteoclast precursor cells and differentiation into functional osteoclasts.
- Local irradiation in combination with bevacizumab enhances radiation control of bone destruction and cancer-induced Pain in a model of bone metastases.
- 2-Methoxyestradiol suppresses osteolytic breast cancer tumor progression in vivo.
- Intramuscular hemangioma: recurrence risk related to surgical margins.
- Osteoclasts direct bystander killing of bone cancer.
- Advances in treating metastatic bone cancer: summary statement for the First Cambridge Conference.
- Biology of bone cancer Pain.
- Novel cytosine deaminase fusion gene enhances the effect of radiation on breast cancer in bone by reducing tumor burden, osteolysis, and skeletal Fracture.
- A customized retroviral vector confers marker gene expression in osteoclast lineage cells.
- Osteoclasts direct bystander killing of cancer cells in vitro.
- Radiation treatment decreases bone cancer Pain through direct effect on tumor cells.
- Analysis of distinct tartrate-resistant acid phosphatase promoter regions in transgenic mice.
- Differential gene expression in liposarcoma, lipoma, and adipose tissue.
- Gene expression in giant-cell tumors.
- Direct and bystander killing of sarcomas by novel cytosine deaminase fusion gene.
- Metastatic bone Disease: future directions.
- Education, employment, insurance, and marital status among 694 survivors of pediatric lower extremity bone tumors: a report from the childhood cancer survivor study.
- Limb salvage and amputation in survivors of pediatric lower-extremity bone tumors: what are the long-term implications?
- Results of treatment for metastatic osteosarcoma with neoadjuvant chemotherapy and surgery.
- Pamidronate decreases tumor-induced osteoclastogenesis in osteopetrotic mice.
- Osteoprotegerin diminishes advanced bone cancer Pain.
- Osteoprotegerin inhibits tumor-induced osteoclastogenesis and bone tumor growth in osteopetrotic mice.
- Cellular and neurochemical remodeling of the spinal cord in bone cancer Pain.
- Murine models of inflammatory, neuropathic and cancer Pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons.
- Review of cellular mechanisms of tumor osteolysis.
- Synovial sarcoma. Large size predicts poor outcome.
- Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal Pain and Pain-related neurochemical reorganization of the spinal cord.
- Evaluation of the feasibility of and results of measuring health-status changes in patients undergoing surgical treatment for skeletal metastases.
- Fixation of large segment femoral allografts using plates augmented with cerclage wires.
- Neurochemical and cellular reorganization of the spinal cord in a murine model of bone cancer Pain.
- Could apoptosis be responsible for localized imbalances in bone cell homeostasis?
- Evaluation of mutant mouse production by mice that are heterogeneous for the Mcfsop gene.
- Osteoclasts are required for bone tumors to grow and destroy bone.
- Measuring health status in patients with skeletal metastases treated by surgery.
- Osteoclast formation during tumor osteolysis does not require proliferating osteoclast precursor cells.
- Human breast cancer induces osteoclast activation and increases the number of osteoclasts at sites of tumor osteolysis.
- Localized, tumor-associated osteolysis involves the recruitment and activation of osteoclasts.
- Tumor osteolysis in osteopetrotic mice.
- Histochemical and immunohistochemical characterization of cells constituting the giant cell tumor of bone.
- Deformity following Fracture in diabetic neuropathic osteoarthropathy. Operative management of adults who have type-I diabetes.
- Osteoarticular allografts for reconstruction after resection of a musculoskeletal tumor in the proximal end of the tibia.
- Effect of quinidine on the renal clearance of digoxin in the presence of low and high serum digoxin concentrations.
- Comparison of pharmacokinetic parameters of intravenous quinidine and quinine in dogs.
- 1,25-Dihydroxyvitamin D3 modulates bone marrow macrophage precursor proliferation and differentiation. Up-regulation of the mannose receptor.
- Fractures associated with neuropathic arthropathy in adults who have juvenile-onset diabetes.
- Bone marrow-derived mononuclear phagocytes autoregulate mannose receptor expression.
- Thrombin binds to murine bone marrow-derived macrophages and enhances colony-stimulating factor-1-driven mitogenesis.
- Function and quality-of-life of survivors of Pelvic and lower extremity osteosarcoma and Ewing''s sarcoma: the Childhood Cancer Survivor Study.
- Bone cancer Pain and the role of RANKL/OPG.
- Advances in understanding bone cancer Pain.
- Radiation treatment decreases bone cancer Pain, osteolysis and tumor size.
- Origins of skeletal Pain: sensory and sympathetic innervation of the mouse femur.
- Molecular mechanisms of cancer Pain.
- Cellular mechanisms of osteolysis.
- New paradigms for therapy for osteosarcoma.
- Response of imatinib-resistant extra-abdominal aggressive fibromatosis to sunitinib: case report and review of the literature on response to tyrosine kinase inhibitors.
- A suspicious vulvar mass diagnosed as a subpubic cartilaginous Cyst.
- Addition of receptor tyrosine kinase inhibitor to radiation increases tumour control in an orthotopic murine model of breast cancer metastasis in bone.
- Gene translocations in musculoskeletal neoplasms.
- Efficacy of systemic morphine suggests a fundamental difference in the mechanisms that generate bone cancer vs inflammatory Pain.
Schools
Rosalind Franklin University Of Medicine ScienceThe Chicago Medical School
University Of Washington Medical Center
Harvard University Health ServStillman Infirmary
Procedures Preformed
- Dressing and-or Debridement of Wound, Infection, or Burn (incl. Negative Pressure Wound Therapy)
- Dural Repair or Other Spinal Spinal Cord Repair
- Excision of Femur or Knee
- Excision of Scapula, Clavicle, Rib, or Sternum
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Conditions Treated
- Ankle Sprain and Achilles Tendon Sprain or Rupture
- Ankylosing Spondylitis
- Arm Fracture (incl. Elbow and Shoulder)
- Ataxia
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Doctors Specialties
- Orthopedic Surgery
- Orthopaedic Surgery
Accepted Insurances
Awards
- America's Top Doctors
- America's Top Doctors for Cancer
- CMS Meaningful Use Stage 1 Certification
- Top MD
- Super Doctor
Education
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Massachusetts General Hospital -
University of Minnesota at Fairview -
Northwestern University Feinberg School of Medicine
Hospital
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University of Minnesota Medical Center, Fairview -
Regions Hospital
Drug Facts
| NPI NUMBER | 1801823711 | |
| NPPES Provider LastName | CLOHISY | |
| NPPES Provider FirstName | DENIS | |
| NPPES Provider ZIPCode | 55454 | |
| NPPES Provider State | MN | |
| Specialty Description | Orthopedic Surgery | |
| Total Claim Count | 55.0 | |
| Distinct Opioid Count | 1.0 | |
| Opioid Claim Count | 17.0 | |
| Percent Opioid Claims | 30.91 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1801823711 |
| Last Name Of The Provider | CLOHISY |
| First Name Of The Provider | DENIS |
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