Assistant Professor, Pathology, University of Texas Southwestern Medical Center, Southwestern Medical School
Pathology
Dr. Dinesh Rakheja, MD
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Dinesh Rakheja, MD is an expert in the field of Pathology. He researched medicine at University of Texas Southwestern Medical School. Doctor Dinesh Rakheja, MD is a published MD. He published 96 publications, including: 'Haemophagocytosis in bone marrow aspirates.'
Publications
- Increased plasma d-2-hydroxyglutarate in isocitrate dehydrogenase 2-mutated blastic plasmacytoid dendritic cell neoplasm.
- Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis.
- Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects.
- Loss of BAP1 protein expression is an independent marker of poor prognosis in patients with low-risk clear cell renal cell carcinoma.
- The neuronal ceroid-lipofuscinoses.
- Single institution experience with tru-cut renal mass biopsy for diagnosing wilms tumor.
- Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes.
- Embryonal rhabdomyosarcoma of the auricle in a child.
- IL-21 promotes the production of anti-DNA IgG but is dispensable for kidney damage in lyn-/- mice.
- IDH mutations in acute myeloid leukemia.
- Immunohistochemical expression of GLUT1 and its correlation with unfavorable histology and TP53 codon 72 polymorphism in Wilms tumors.
- Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney.
- Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours.
- DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors.
- The emerging role of d-2-hydroxyglutarate as an oncometabolite in hematolymphoid and central nervous system neoplasms.
- Congenital hairy polyp of the palatopharyngeus muscle.
- A zebrafish transgenic model of Ewing''s sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis.
- Prevalence of the Alternative Lengthening of Telomeres Telomere Maintenance Mechanism in Human Cancer Subtypes.
- Adverse effects of simulated hyper- and hypo-phosphatemia on endothelial cell function and viability.
- Mutation in the type IB bone morphogenetic protein receptor alk6b impairs germ-cell differentiation and causes germ-cell tumors in zebrafish.
- Bone morphogenetic protein signalling activity distinguishes histological subsets of paediatric germ cell tumours.
- Activated NOTCH2 is overexpressed in hepatoblastomas: an immunohistochemical study.
- The green tea polyphenol (-)-epigallocatechin-3-gallate ameliorates experimental immune-mediated glomerulonephritis.
- High incidence of IDH mutations in acute myeloid leukaemia with cuplike nuclei.
- Proliferative nodules arising within congenital melanocytic nevi: a histologic, immunohistochemical, and molecular analyses of 43 cases.
- A potential role for targeted therapy in a subset of metastasizing adnexal carcinomas.
- Immunohistochemical expression of embryonic stem cell markers in malignant rhabdoid tumors.
- High-resolution array CGH identifies common mechanisms that drive embryonal rhabdomyosarcoma pathogenesis.
- Immunoexpression of SALL4 in Wilms tumors and developing kidney.
- Isocitrate dehydrogenase 1/2 mutational analyses and 2-hydroxyglutarate measurements in Wilms tumors.
- Papillary thyroid carcinoma shows elevated levels of 2-hydroxyglutarate.
- Intratumoral expression level of epidermal growth factor receptor and cytokeratin 5/6 is significantly associated with nodal and distant metastases in patients with ba...
- Immunohistochemical expression of neural cell adhesion molecule in Wilms tumors, nephrogenic rests, and fetal and postnatal renal cortices.
- Fetal akinesia deformation sequence and neuroaxonal dystrophy without PLA2G6 mutation.
- L-2-hydroxyglutaric aciduria and multiple acyl-coenzyme A dehydrogenase deficiency are distinct metabolic disorders.
- Wilms tumor in a child with L-2-hydroxyglutaric aciduria.
- Cell cycle inhibition and apoptosis induced by curcumin in Ewing sarcoma cell line SK-NEP-1.
- Diagnostic utility of SALL4 in primary germ cell tumors of the central nervous system: a study of 77 cases.
- Establishment and characterization of a cancer cell line derived from an aggressive childhood liver tumor.
- Diagnostic utility of SALL4 in extragonadal yolk sac tumors: an immunohistochemical study of 59 cases with comparison to placental-like alkaline phosphatase, alpha-fet...
- Atypical and malignant hidradenomas: a histological and immunohistochemical study.
- A novel SOX9 mutation, 972delC, causes 46,XY sex-reversed campomelic dysplasia with nephrocalcinosis, urolithiasis, and dysgerminoma.
- The function of CLN3P, the Batten disease protein.
- The aging kidney.
- A subset of cranial fasciitis is associated with dysregulation of the Wnt/beta-catenin pathway.
- Unsuspected, disseminated coccidioidomycosis without maternofetal morbidity diagnosed by placental examination: case report and review of the literature.
- Highly active antiretroviral therapy does not affect mitochondrial beta-oxidation of fatty acids: an in vitro study in fibroblasts.
- Translocation (4;19)(q35;q13.1)-associated primitive round cell sarcoma: report of a case and review of the literature.
- Juvenile neuronal ceroid-lipofuscinosis (Batten disease): a brief review and update.
- A severely affected female infant with x-linked dominant chondrodysplasia punctata: a case report and a brief review of the literature.
- Precholesterol sterols accumulate in lipid rafts of patients with Smith-Lemli-Opitz syndrome and X-linked dominant chondrodysplasia punctata.
- Targeting the apoptotic machinery in pancreatic cancers using small-molecule antagonists of the X-linked inhibitor of apoptosis protein.
- Phosphorylated histone H3, Ki-67, p21, fatty acid synthase, and cleaved caspase-3 expression in benign and atypical granular cell tumors.
- Congenital self-healing reticulohistiocytosis (Hashimoto-Pritzker disease): ten-year experience at Dallas Children's Medical Center.
- Clear cell odontogenic carcinoma: a diagnostic and therapeutic dilemma.
- CLN3P, the Batten's disease protein, is a novel palmitoyl-protein Delta-9 desaturase.
- Extrahepatic biliary atresia demonstrates abnormal persistence of HES1 protein in neonatal biliary epithelium: an immunohistochemical study.
- Sclerosing lobular hyperplasia of breast: cytomorphologic and histomorphologic features: a case report.
- Absence of expression of SMARCB1/INI1 in malignant rhabdoid tumors of the central nervous system, kidneys and soft tissue: an immunohistochemical study with implicatio...
- Over-expression of CLN3P, the Batten disease protein, inhibits PANDER-induced apoptosis in neuroblastoma cells: further evidence that CLN3P has anti-apoptotic properties.
- Primary mucinous adenocarcinoma of the thymus: a case report and review of the literature.
- Pediatric renal cell carcinomas with Xp11.2 rearrangements are immunoreactive for hMLH1 and hMSH2 proteins.
- Infection-associated haemophagocytosis: the tropical spectrum.
- Increased ratio of saturated to unsaturated C18 fatty acids in colonic adenocarcinoma: implications for cryotherapy and lipid raft function.
- Fatty acid synthase expression in cutaneous melanocytic neoplasms.
- Thyroid enlargement, hyperthyroidism, and antibodies to thyroglobulin and thyroid peroxidase in an 11-year-old girl.
- Immunohistochemical expression of beta-catenin in solitary fibrous tumors.
- "Proximal-type" and classic epithelioid sarcomas represent a clinicopathologic continuum: case report.
- Renal metanephric adenoma with previously unreported cytogenetic abnormalities: case report and review of the literature.
- Pathologic quiz case: sphenoid sinus mass in a 12-year-old girl. Infrasellar adamantinomatous craniopharyngioma.
- Extrapleural benign solitary fibrous tumor in the shoulder of a 9-year-old girl: case report and review of the literature.
- Infantile cystinosis.
- Pathologic quiz case: laryngeal lesion in an elderly man. Verrucous carcinoma of the larynx.
- Helicobacter heilmannii infection in a child.
- Dysmorphic villi mimicking partial mole in a case with del(18)(q21).
- Characterization of inflammation in syphilitic villitis and in villitis of unknown etiology.
- Translocation (10;17)(q22;p13): a recurring translocation in clear cell sarcoma of kidney.
- Hepatic mesenchymal hamartoma with translocation involving chromosome band 19q13.4: a recurrent abnormality.
- Hydrolethalus syndrome, in contrast to Smith-Lemli-Opitz syndrome, is not due to a defect in post-squalene cholesterol biosynthesis: a case report.
- CLN3P, the Batten disease protein, localizes to membrane lipid rafts (detergent-resistant membranes).
- Multilocular thymic cyst associated with mature mediastinal teratoma: a report of 2 cases.
- Carnitine palmitoyltransferase II deficiency: a clinical, biochemical, and molecular review.
- Pathologic quiz case: a woman with right facial nerve paralysis. Endolymphatic sac tumor associated with von Hippel-Lindau disease.
- Pathologic quiz case: upper aerodigestive tract mass in a 90-year-old woman.
- Biochemical abnormality associated with Smith-Lemli-Opitz syndrome in an infant with features of Rutledge multiple congenital anomaly syndrome confirms that the latter...
- Human placenta metabolizes fatty acids: implications for fetal fatty acid oxidation disorders and maternal liver diseases.
- Pediatric pathology: a case report highlighting its singular niche.
- Rosette formation within a proliferative nodule of an atypical combined melanocytic nevus in an adult.
- Cystic fibrosis and Chiari type I malformation: autopsy study of two infants with a rare association.
- Pathologic quiz case. Cystic and solid ovarian tumor in a 43-year-old woman.
- Long-chain L-3-hydroxyacyl-coenzyme a dehydrogenase deficiency: a molecular and biochemical review.
- Evidence for fatty acid oxidation in human placenta, and the relationship of fatty acid oxidation enzyme activities with gestational age.
- Intratubular embryonal carcinoma.
- Clinical, hematological and histomorphological profile of myelodysplastic syndrome.
- Haemophagocytosis in bone marrow aspirates.
Doctors Specialties
- Pediatric Pathology
- Pathology
Accepted Insurances
Education
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University of Texas Southwestern Medical School -
All India Institute of Medical Sciences
Hospital
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Parkland Health & Hospital System -
Children's Health System of Texas -
University of Texas Southwestern Medical Center
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