Associate Professor, Anesthesiology, Mayo Medical School
Anesthesiology
Dr. Eduardo N. Chini, MD
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Eduardo N. Chini practices Anesthesiology. He over the years received 10 awards: "Glenn/AFAR BIG Award", "Scientists Development Grant", "The Edward C. Kendall Award for Excellence of Basic Research", "Duane K. Rorie, M.D., Award for Excellence in Research, Department of Anesthesiology", "Richard A. Theye, M.D., Award for Excellence in Clinical Research, Department of Anesthesiology", "Grant-in-Aid", "Research Fellowship", "Traveling Trainee Investigation Award", "Visiting Scientific Fellowship" and "Fellowship". Eduardo Chini is a published physician. He published 79 publications, including: 'mRNAs coding for the calcium-sensing receptor along the rat nephron: effect of a low-phosphate diet.' He is registered with Medicare and accepts Medicare payments.
Publications
- Deleted in breast cancer 1 limits adipose tissue fat accumulation and plays a key role in the development of metabolic syndrome phenotype.
- Deleted in Breast Cancer 1 regulates cellular senescence during obesity.
- Deleted in Breast Cancer 1 (DBC1) Protein Regulates Hepatic Gluconeogenesis.
- Targeting of NAD Metabolism in Pancreatic Cancer Cells: Potential Novel Therapy for Pancreatic Tumors.
- Resveratrol delays Wallerian degeneration in a NAD(+) and DBC1 dependent manner.
- DBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erbα.
- Flavonoid Apigenin Is an Inhibitor of the NAD+ase CD38: Implications for Cellular NAD+ Metabolism, Protein Acetylation, and Treatment of Metabolic Syndrome.
- Altered behavioral and metabolic circadian rhythms in mice with disrupted NAD+ oscillation.
- HDAC3 is negatively regulated by the nuclear protein DBC1.
- Dietary restriction: standing up for sirtuins.
- Spontaneous activity, economy of activity, and resistance to diet-induced obesity in rats bred for high intrinsic aerobic capacity.
- Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice.
- Endurance capacity, not body size, determines physical activity levels: role of skeletal muscle PEPCK.
- The enzyme CD38 (a NAD glycohydrolase, EC 3.2.2.5) is necessary for the development of diet-induced obesity.
- Reduction in soluble guanylyl cyclase-specific activity following prolonged treatment of porcine pulmonary artery with nitric oxide.
- NAADP as a second messenger: neither CD38 nor base-exchange reaction are necessary for in vivo generation of NAADP in myometrial cells.
- Integrin ligands mobilize Ca2+ from ryanodine receptor-gated stores and lysosome-related acidic organelles in pulmonary arterial smooth muscle cells.
- Regulation of SIRT 1 mediated NAD dependent deacetylation: a novel role for the multifunctional enzyme CD38.
- Agonist-induced cyclic ADP ribose production in airway smooth muscle.
- Role of transient receptor potential C3 in TNF-alpha-enhanced calcium influx in human airway myocytes.
- Differential effects of volatile anesthetics on M3 muscarinic receptor coupling to the Galphaq heterotrimeric G protein.
- Regulation of intracellular levels of NAD: a novel role for CD38.
- Complications after unintentional intra-arterial injection of drugs: risks, outcomes, and management strategies.
- Role of the second-messenger cyclic-adenosine 5'-diphosphate-ribose on adrenocorticotropin secretion from pituitary cells.
- Postoperative outcome of patients with narcolepsy. A retrospective analysis.
- Role of CD38 in myometrial Ca2+ transients: modulation by progesterone.
- Hypertensive crisis in a patient undergoing percutaneous radiofrequency ablation of an adrenal mass under general anesthesia.
- The role of cyclic-ADP-ribose-signaling pathway in oxytocin-induced Ca2+ transients in human myometrium cells.
- The cyclic-ADP-ribose signaling pathway in human myometrium.
- Effect of halothane on cADP-ribose-induced Ca(2+) release system in tracheal smooth muscle.
- Nicotinic acid adenine dinucleotide phosphate: a new intracellular second messenger?
- CD38 as a regulator of cellular NAD: a novel potential pharmacological target for metabolic conditions.
- To be or not to be ... nicotinic acid adenine dinucleotide phosphate (NAADP): a new intracellular second messenger?
- Interactions between intracellular Ca2+ stores: Ca2+ released from the NAADP pool potentiates cADPR-induced Ca2+ release.
- Metabolism of cyclic ADP-ribose: Zinc is an endogenous modulator of the cyclase/NAD glycohydrolase ratio of a CD38-like enzyme from human seminal fluid.
- Abscisic acid controls calcium-dependent egress and development in Toxoplasma gondii.
- Calcium regulation and signaling in apicomplexan parasites.
- Plants, endosymbionts and parasites: Abscisic acid and calcium signaling.
- Evidence that the cADPR signalling pathway controls calcium-mediated microneme secretion in Toxoplasma gondii.
- CD38 is the major enzyme responsible for synthesis of nicotinic acid-adenine dinucleotide phosphate in mammalian tissues.
- CD38 expression, function, and gene resequencing in a human lymphoblastoid cell line-based model system.
- Modulation of store-operated Ca2+ entry by cyclic-ADP-ribose.
- The enhancement of Ca2+ efflux from sarcoplasmic reticulum vesicles by urea.
- Monosaccharides and disaccharides decrease the Km for phosphorylation of a membrane-bound enzyme ATPase.
- K(+)- and Mg2(+)-dependent hydrolysis of acetyl phosphate catalyzed by the (Ca2+ + Mg2+)-ATPase of sarcoplasmic reticulum.
- Specific modulation of cyclic ADP-ribose-induced Ca2+ release by polyamines.
- Adrenomedullin suppresses mitogenesis in rat mesangial cells via cAMP pathway.
- Unique localization of mRNA encoding plasma membrane Ca2+ pump isoform 3 in rat thin descending loop of Henle.
- All-trans-retinoic acid stimulates synthesis of cyclic ADP-ribose in renal LLC-PK1 cells.
- Inhibitors of cyclic nucleotide phosphodiesterase isozymes type-III and type-IV suppress mitogenesis of rat mesangial cells.
- Different thermostabilities of sarcoplasmic reticulum (Ca2+ + Mg2+)-ATPases from rabbit and trout muscles.
- Enzymatic synthesis and degradation of nicotinate adenine dinucleotide phosphate (NAADP), a Ca(2+)-releasing agonist, in rat tissues.
- Nicotinate adenine dinucleotide phosphate (NAADP) triggers a specific calcium release system in sea urchin eggs.
- Metabolism of cyclic ADP-ribose in opossum kidney renal epithelial cells.
- Formation of reactive oxygen metabolites in glomeruli is suppressed by inhibition of cAMP phosphodiesterase isozyme type IV.
- The Ca(2+)-transporting ATPases of rabbit and trout exhibit different pH- and temperature-dependences.
- Ca2+ release triggered by nicotinate adenine dinucleotide phosphate in intact sea urchin eggs.
- beta-Estradiol inhibits Na+-P(i) cotransport across renal brush border membranes from ovarectomized rats.
- Nicotinate-adenine dinucleotide phosphate-induced Ca(2+)-release does not behave as a Ca(2+)-induced Ca(2+)-release system.
- Palmitoyl-CoA potentiates the Ca2+ release elicited by cyclic ADP-ribose.
- Adenine nucleotide diphosphates: emerging second messengers acting via intracellular Ca2+ release.
- Compartmentalization of cAMP signaling in mesangial cells by phosphodiesterase isozymes PDE3 and PDE4. Regulation of superoxidation and mitogenesis.
- Cyclic ADP-ribose signaling in sea urchin gametes: metabolism in spermatozoa.
- Cyclic ADP-ribose metabolism in rat kidney: high capacity for synthesis in glomeruli.
- Effect of estrogen upon cyclic ADP ribose metabolism: beta-estradiol stimulates ADP ribosyl cyclase in rat uterus.
- Cytoprotective effects of adrenomedullin in glomerular cell injury: central role of cAMP signaling pathway.
- mRNA encoding four isoforms of the plasma membrane calcium pump and their variants in rat kidney and nephron segments.
- Differential effect of pH upon cyclic-ADP-ribose and nicotinate-adenine dinucleotide phosphate-induced Ca2+ release systems.
- mRNAs coding for the calcium-sensing receptor along the rat nephron: effect of a low-phosphate diet.
- Differential effect of glycolytic intermediaries upon cyclic ADP-ribose-, inositol 1',4',5'-trisphosphate-, and nicotinate adenine dinucleotide phosphate-induced Ca(2+...
- Synthesis of NAADP and cADPR in mitochondria.
- Selective decrease of mRNAs encoding plasma membrane calcium pump isoforms 2 and 3 in rat kidney.
- FK506 (tacrolimus) increases halothane-induced Ca2+ release from skeletal muscle sarcoplasmic reticulum.
- ADP-Ribosyl cyclase in rat vascular smooth muscle cells: properties and regulation.
- Loss of HSulf-1 promotes altered lipid metabolism in ovarian cancer.
- Nicotinic acid adenine dinucleotide phosphate: a new Ca2+ releasing agent in kidney.
- Nicotinic acid-adenine dinucleotide phosphate (NAADP) elicits specific microsomal Ca2+ release from mammalian cells.
- Selected contribution: effect of volatile anesthetics on cADP-ribose-induced Ca(2+) release system.
Doctors Specialties
- Anesthesiology
Accepted Insurances
Awards
- Glenn/AFAR BIG Award
- Scientists Development Grant
- The Edward C. Kendall Award for Excellence of Basic Research
- Duane K. Rorie, M.D., Award for Excellence in Research, Department of Anesthesiology
- Richard A. Theye, M.D., Award for Excellence in Clinical Research, Department of Anesthesiology
- Grant-in-Aid
- Research Fellowship
- Traveling Trainee Investigation Award
- Visiting Scientific Fellowship
- Fellowship
Education
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Mayo School of Graduate Medical Education -
Faculdade de Medicina da Universidade Federal do Rio de Janeiro
Hospital
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Mayo Clinic - Rochester, Minnesota
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1275510117 |
| Last Name Of The Provider | CHINI |
| First Name Of The Provider | EDUARDO |
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