Professor, Medicine, Physiology and Psychiatry, UCLA School of Medicine

Gastroenterology

Emeran Mayer works in the field of Gastroenterology. He has 11 awards "CMS Meaningful Use Stage 1 Certification", "2009 Senior Basic Scientist Award", "Elected to Membership", "2004 Senior Research Scientist Award", "Janssen Award for Outstanding Achievements in Gastroenterology", "Membership (Young Turks)", "Clinical Research Award", "Elected Member", "Physician Scientist Award", "Award of 6-year Scholarship" and "Super Doctor". Dr. Emeran A. Mayer is a published doctor and has 101 publications published. The lastest was: 'Genome-wide DNA methylation profiling of peripheral blood mononuclear cells in irritable bowel syndrome.'

Publications

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• Genome-wide DNA methylation profiling of peripheral blood mononuclear cells in irritable bowel Syndrome.
• Altered brain responses in subjects with irritable bowel syndrome during cued and uncued Pain expectation.
• Imaging brain mechanisms in chronic visceral Pain.
• Chronic psychological stress in high-anxiety rats induces sustained bladder hyperalgesia.
• Increased brain gray matter in the primary somatosensory cortex is associated with increased Pain and mood disturbance in patients with interstitial cystitis/Painful b...
• Neonatal stress from limited bedding elicits visceral hyperalgesia in adult rats.
• Interactions of early adversity with stress-related gene polymorphisms impact regional brain structure in females.
• Gastrointestinal dysbiosis.
• Gut microbes and the brain: paradigm shift in neuroscience.
• Altered brain-gut axis in autism: Comorbidity or causative mechanisms?
• Preliminary structural MRI based brain classification of chronic pelvic Pain: A MAPP Network Study.
• The perfect neuroimaging-genetics-computation storm: collision of petabytes of data, millions of hardware devices and thousands of software tools.
• Alterations in resting state oscillations and connectivity within sensory and motor networks in women with interstitial cystitis/Painful bladder syndrome.
• Impaired emotional learning and involvement of the corticotropin-releasing factor signaling system in patients with irritable bowel Syndrome.
• Diffusion tensor imaging detects microstructural reorganization in the brain associated with chronic irritable bowel Syndrome.
• Irritable Bowel Syndrome in female patients is associated with alterations in structural brain networks.
• Identification of a Functional TPH1 Polymorphism Associated With Irritable Bowel Syndrome Bowel Habit Subtypes.
• Autonomic response to a visceral stressor is dysregulated in irritable bowel Syndrome and correlates with duration of disease.
• Sex differences in emotion-related cognitive processes in irritable bowel Syndrome and healthy control subjects.
• Differences in brain responses between lean and obese women to a sweetened drink.
• Alterations in prefrontal-limbic functional activation and connectivity in chronic stress-induced visceral hyperalgesia.
• Dyspepsia: Structural changes in functional gastrointestinal Disorders.
• Type, Rather than Number, of Mental and Physical Comorbidities Increases the Severity of Symptoms in Patients with Irritable Bowel Syndrome.
• Diminished neurokinin-1 receptor availability in patients with two forms of chronic visceral Pain.
• Consumption of Fermented Milk Product with Probiotic Modulates Brain Activity.
• Gut sensations - Not so gut specific after all?
• Randomised clinical trial: symptoms of the irritable bowel Syndrome are improved by a psycho-education group intervention.
• Evidence for alterations in central noradrenergic signaling in irritable bowel Syndrome.
• Pain, affective symptoms, and cognitive deficits in patients with cerebral dopamine dysfunction.
• The right inhibition? callosal correlates of hand performance in healthy children and adolescents callosal correlates of hand performance.
• One-year test-retest reliability of intrinsic connectivity network fMRI in older adults.
• Association between Early Adverse Life Events and Irritable Bowel Syndrome.
• Serum and Colonic Mucosal Immune Markers in Irritable Bowel Syndrome.
• Brain Responses to Visceral Stimuli Reflect Visceral Sensitivity Thresholds in Patients with Irritable Bowel Syndrome.
• Gastrointestinal and Psychological Mediators of Health-Related Quality of Life in IBS and IBD: A Structural Equation Modeling Analysis.
• Functional brain activation during retrieval of visceral Pain-conditioned passive avoidance in the rat.
• Corticotropin-Releasing Factor Receptor 1 Antagonist Alters Regional Activation and Effective Connectivity in an Emotional-Arousal Circuit during Expectation of Abdomi...
• The Effects of Acute and Chronic Psychological Stress on Bladder Function in a Rodent Model.
• Gut feelings: the emerging biology of gut-brain communication.
• Role of astrocytes and altered regulation of spinal glutamatergic neurotransmission in stress-induced visceral hyperalgesia in rats.
• The HTR3A Polymorphism c. -42C>T Is Associated With Amygdala Responsiveness in Patients With Irritable Bowel Syndrome.
• Common component classification: What can we learn from machine learning?
• Impact of Mindfulness-Based Stress Reduction training on intrinsic brain connectivity.
• The search for biomarkers and endophenotypes in functional gastrointestinal Disorders.
• A cognitive-behavioral treatment for irritable bowel Syndrome using interoceptive exposure to visceral sensations.
• Modulation of nociceptive and acoustic startle responses to an unpredictable threat in men and women.
• The brain-gut axis in Abdominal pain syndromes.
• Quantitative meta-analysis identifies brain regions activated during rectal distension in irritable bowel Syndrome.
• Gating of sensory information differs in patients with interstitial cystitis/Painful bladder syndrome.
• Regional gray matter density changes in brains of patients with irritable bowel Syndrome.
• Genetic approaches to functional gastrointestinal Disorders.
• Childhood trauma is associated with hypothalamic-pituitary-adrenal axis responsiveness in irritable bowel Syndrome.
• The power of placebo in pediatric functional gastrointestinal Disease.
• Brain networks underlying perceptual habituation to repeated aversive visceral stimuli in patients with irritable bowel Syndrome.
• Developing irritable bowel Syndrome guidelines through meta-analyses: does the emperor really have new clothes?
• Increased startle responses in interstitial cystitis: evidence for central hyperresponsiveness to visceral related threat.
• Role of spinal microglia in visceral hyperalgesia and NK1R up-regulation in a rat model of chronic stress.
• The vital role of ORWH.
• Involvement of vasopressin 3 receptors in chronic psychological stress-induced visceral hyperalgesia in rats.
• Studying the brain-gut axis with pharmacological imaging.
• Predictors of patient-assessed illness severity in irritable bowel Syndrome.
• Increased acoustic startle responses in IBS patients during Abdominal and nonAbdominal threat.
• The challenge of studying the biology of complex, symptom-based GI Disorders.
• Clinical practice. Irritable bowel Syndrome.
• Corticotropin-releasing factor type 1 receptors mediate the visceral hyperalgesia induced by repeated psychological stress in rats.
• The effect of auditory stress on perception of intraesophageal acid in patients with Gastroesophageal reflux disease.
• Effect of abuse history on Pain reports and brain responses to aversive visceral stimulation: an FMRI study.
• Reduced brainstem inhibition during anticipated pelvic visceral Pain correlates with enhanced brain response to the visceral stimulus in women with irritable bowel syn...
• Primary endpoints for irritable bowel Syndrome trials: a review of performance of endpoints.
• Enteric neuroscience: the dawn of a new discipline.
• Psychometric properties of the Early Trauma Inventory-Self Report.
• The central role of gastrointestinal-specific anxiety in irritable bowel Syndrome: further validation of the visceral sensitivity index.
• Neuroimaging of the brain-gut axis: from basic understanding to treatment of functional GI Disorders.
• Effect of sex on perception of rectosigmoid stimuli in irritable bowel Syndrome.
• Longitudinal change in perceptual and brain activation response to visceral stimuli in irritable bowel Syndrome patients.
• Sex differences in regional brain response to aversive pelvic visceral stimuli.
• Commentary on peripheral and central contributions to hyperalgesia in irritable bowel Syndrome.
• Experimental colitis modulates the functional properties of NMDA receptors in dorsal root ganglia neurons.
• The role of neurokinin 1 receptors in the maintenance of visceral hyperalgesia induced by repeated stress in rats.
• Functional Abdominal pain syndrome.
• Brain imaging in IBS: drawing the line between cognitive and non-cognitive processes.
• Is a negative colonoscopy associated with reassurance or improved health-related quality of life in irritable bowel Syndrome?
• Pain perception in irritable bowel syndrome.
• Corticotropin-releasing factor receptor 1 mediates acute and delayed stress-induced visceral hyperalgesia in maternally separated Long-Evans rats.
• Repeated exposure to water avoidance stress in rats: a new model for sustained visceral hyperalgesia.
• Characterization of the alternating bowel habit subtype in patients with irritable bowel Syndrome.
• A dose-ranging, phase II study of the efficacy and safety of alosetron in men with diarrhea-predominant IBS.
• Racial differences in the impact of irritable bowel Syndrome on health-related quality of life.
• Clinical determinants of health-related quality of life in patients with irritable bowel Syndrome.
• Inflammation in irritable bowel Syndrome: curiosity or culprit.
• Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia.
• The effect of life stress on symptoms of heartburn.
• The neural correlates of placebo effects: a disruption account.
• Delayed stress-induced colonic hypersensitivity in male Wistar rats: role of neurokinin-1 and corticotropin-releasing factor-1 receptors.
• Collaborative health for IBS.
• Dissecting the components of the central response to stress.
• Current insights into the pathophysiology of irritable bowel Syndrome.
• Inflammatory bowel disease and irritable bowel Syndrome: separate or unified?
• Sex-related differences in IBS patients: central processing of visceral stimuli.
• Brain responses to visceral and somatic stimuli in patients with irritable bowel Syndrome with and without fibromyalgia.

Schools

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• Ludwig Maximiliams University Medical Faculty

• Va Wadsworth

• Vancouver Genl Hospital

• UCLA Va Wadsworth

Conditions Treated

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• Abdominal Pain
• Diaphragmatic and-or Hiatal Hernia
• Dysphagia
• Gas-Bloat Syndrome
• View All

Doctors Specialties

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• Gastroenterology

Accepted Insurances

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Awards

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• CMS Meaningful Use Stage 1 Certification
• 2009 Senior Basic Scientist Award
• Elected to Membership
• 2004 Senior Research Scientist Award
• Janssen Award for Outstanding Achievements in Gastroenterology
• Membership (“Young Turks”)
• Clinical Research Award
• Elected Member
• Physician Scientist Award
• Award of 6-year Scholarship
• Super Doctor

Education

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• Ludwig Maximilian University of Munich Faculty of Medicine

Hospital

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• Ronald Reagan UCLA Medical Center

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