Professor of Internal Medicine; Molecular and Integrative Physiology; Cell and Developmental Biology - University Mich Medical School
Endocrinology
Gary Hammer practices Endocrinology. He went to Tufts University School of Medicine. Tufts University School of Medicine is ranked 49 in research and 52 in primary care medicine He has 28 awards "Elected Member", "The One Hundred, Inductee", "America's Top Doctors", "Edwin B. Astwood Award Lecture for Outstanding Research in Endocrinology", "America's Top Doctors for Cancer", "Inductee", "CMS Meaningful Use Stage 1 Certification", "Outstanding Reviewer Award", "Jerome Conn Award for Outstanding Research", "Millie Schembechler Endowed Chair of Adrenal Cancer", "Award Winner", "Merck Senior Fellow Award", "Research Award", "Outstanding Overall Teaching Contribution for Medical School-first Year, Nominee", "Outstanding Small Group Instructor for Medical School-second Year, Nominee", "Outstanding Clinical Preceptor for Medical School-second Year", "Outstanding Small Group Instructor for Medical School-first Year, Nominee", "Outstanding Achievement in Neuroscience Award", "Second Prize", "Third Prize", "Kidder Medal for Outstanding Senior Male", "Outstanding Senior in Department of Psychology", "Phi Beta Kappa Inductee", "Sigma Xi Inductee", "Wasson Award for Outstanding Scholar-Athlete", "Boulder Society Inductee", "Mortar Board Inductee" and "Outstanding Contribution to Research in Psychology Award". Gary D. Hammer has written publications. He has 89 publications published with PubMed. The lastest paper is: 'Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression.' Dr. Gary D. Hammer is registered with Medicare.
Publications
- Mouse models of adrenocortical tumors.
- Linsitinib (OSI-906) versus placebo for patients with locally advanced or metastatic adrenocortical carcinoma: a double-blind, randomised, phase 3 study.
- Adjuvant Radiation Therapy Improves Local Control After Surgical Resection in Patients With Localized Adrenocortical Carcinoma.
- Hedgehog signaling and steroidogenesis.
- Regulation of the adrenocortical stem cell niche: implications for disease.
- Erratum to: The Combination of Insulin-Like Growth Factor Receptor 1 (IGF1R) Antibody Cixutumumab and Mitotane as a First-Line Therapy for Patients with Recurrent/Meta...
- Wnt-Signaling Inhibits Adrenal Steroidogenesis by Cell-Autonomous and Non-Cell-Autonomous Mechanisms.
- Withanolides are Potent Novel Targeted Therapeutic Agents Against Adrenocortical Carcinomas.
- Transcutaneous biopsy of adrenocortical carcinoma is rarely helpful in diagnosis, potentially harmful, but does not affect patient outcome.
- The Combination of Insulin-Like Growth Factor Receptor 1 (IGF1R) Antibody Cixutumumab and Mitotane as a First-Line Therapy for Patients with Recurrent/Metastatic Adren...
- Adjuvant Therapies, Patient and Tumor Characteristics Associated with Survival of Adult Patients with Adrenocortical Carcinoma.
- Genetics and epigenetics of adrenocortical tumors.
- Fetal Adrenal capsular cells serve as progenitor cells for steroidogenic and stromal adrenocortical cell lineages in M. musculus.
- Adrenocortical carcinoma is a lynch Syndrome-associated cancer.
- An oncocytic Adrenal tumour in a patient with Birt-Hogg-Dubé syndrome.
- Dicer deficiency reveals microRNAs predicted to control gene expression in the developing Adrenal cortex.
- Prevalence of germline TP53 mutations in a prospective series of unselected patients with adrenocortical carcinoma.
- Resection of adrenocortical carcinoma is less complete and local recurrence occurs sooner and more often after laparoscopic Adrenalectomy than after open Adrenalectomy.
- Progression to Adrenocortical Tumorigenesis in Mice and Humans through Insulin-Like Growth Factor 2 and β-Catenin.
- Upregulated JAG1 Enhances Cell Proliferation in Adrenocortical Carcinoma.
- Worsening Central Sarcopenia and Increasing Intra-Abdominal Fat Correlate with Decreased Survival in Patients with Adrenocortical Carcinoma.
- Adrenal cancer: clinical advances.
- Adrenal Cancer: Scientific Advances.
- Evidence of Adrenal Failure in Aging Dax1-Deficient Mice.
- Mebendazole Monotherapy Provides Long-Term Disease Control in Metastatic Adrenocortical Carcinoma.
- Aged PROP1 Deficient Dwarf Mice Maintain ACTH Production.
- Dax1 up-regulates Oct4 expression in mouse embryonic stem cells via LRH-1 and SRA.
- Inhibin-A antagonizes TGFbeta2 signaling by down-regulating cell surface expression of the TGFbeta coreceptor betaglycan.
- Management of adrenocortical carcinoma.
- Genetic p53 deficiency partially rescues the adrenocortical dysplasia phenoType at the expense of increased tumorigenesis.
- In search of adrenocortical stem and progenitor cells.
- Dax-1 and steroid receptor RNA activator (SRA) function as transcriptional coactivators for steroidogenic factor 1 in steroidogenesis.
- SUMOylation inhibits SF-1 activity by reducing CDK7-mediated serine 203 phosphorylation.
- Preclinical targeting of the Type I insulin-like growth factor receptor in adrenocortical carcinoma.
- The role of radiologic studies in the evaluation and management of primary Hyperaldosteronism.
- Contributions of specificity protein-1 and steroidogenic factor 1 to Adcy4 expression in Y1 mouse Adrenal cells.
- Evaluation of telomere length maintenance mechanisms in adrenocortical carcinoma.
- The molecular genetics of adrenocortical carcinoma.
- Genetic removal of Smad3 from inhibin-null mice attenuates tumor progression by uncoupling extracellular mitogenic signals from the cell cycle machinery.
- Telomere protection by mammalian Pot1 requires interaction with Tpp1.
- Pre-B-cell transcription factor 1 and steroidogenic factor 1 synergistically regulate adrenocortical growth and steroidogenesis.
- Origin and identity of adrenocortical tumors in inhibin knockout mice: implications for cellular plasticity in the Adrenal cortex.
- Reciprocal regulation of a glucocorticoid receptor-steroidogenic factor-1 transcription complex on the Dax-1 promoter by glucocorticoids and adrenocorticotropic hormon...
- IMAGe association and congenital Adrenal hypoplasia: no disease-causing mutations found in the ACD gene.
- Steroid receptor coactivator-1-deficient mice exhibit altered hypothalamic-pituitary-Adrenal axis function.
- Adrenocorticotropic hormone-mediated signaling cascades coordinate a cyclic pattern of steroidogenic factor 1-dependent transcriptional activation.
- Genetic analysis of Adrenal absence: agenesis and aplasia.
- Minireview: transcriptional regulation of adrenocortical development.
- Transsphenoidal microsurgery for Cushing's disease: initial outcome and long-term results.
- Mechanistic roles of inhibin as a tumor suppressor in the Adrenal cortex.
- T-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factors.
- Convergence of Wnt signaling and steroidogenic factor-1 (SF-1) on transcription of the rat inhibin alpha gene.
- Activin induces x-zone apoptosis that inhibits luteinizing hormone-dependent adrenocortical tumor formation in inhibin-deficient mice.
- Steroidogenic factor-1 is essential for compensatory Adrenal growth following unilateral Adrenalectomy.
- Recent insights into organogenesis of the Adrenal cortex.
- Ectopic pro-opiomelanocortin Syndrome.
- Interaction between Dax-1 and steroidogenic factor-1 in vivo: increased Adrenal responsiveness to ACTH in the absence of Dax-1.
- Adrenocortical stem and progenitor cells: unifying model of two proposed origins.
- Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells.
- Proposal for modification of the ENSAT staging system for adrenocortical carcinoma using tumor grade.
- LRH-1 and Nanog regulate Dax1 transcription in mouse embryonic stem cells.
- GSK3beta and beta-catenin modulate radiation cytotoxicity in pancreatic Cancer.
- Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator.
- Safety, tolerability, and pharmacokinetics of the anti-IGF-1R monoclonal antibody figitumumab in patients with refractory adrenocortical carcinoma.
- Targeted disruption of beta-catenin in Sf1-expressing cells impairs development and maintenance of the Adrenal cortex.
- Adrenocortical cells with stem/progenitor cell properties: recent advances.
- Novel polymorphisms and lack of mutations in the ACD gene in patients with ACTH resistance Syndromes.
- Tpp1/Acd maintains genomic stability through a complex role in telomere protection.
- Gonadectomy in mice of the inbred strain CE/J induces proliferation of sub-capsular Adrenal cells expressing gonadal marker genes.
- Nuclear receptors Sf1 and Dax1 function cooperatively to mediate somatic cell differentiation during testis development.
- Role of the inhibin/activin system and luteinizing hormone in adrenocortical tumorigenesis.
- Molecular classification and prognostication of adrenocortical tumors by transcriptome profiling.
- Laparoscopic resection is inappropriate in patients with known or suspected adrenocortical carcinoma.
- Role of phosphorylation, gene dosage and Dax-1 in SF-1 mediated steroidogenesis.
- Adjuvant and definitive radiotherapy for adrenocortical carcinoma.
- Wnt/betacatenin signaling in adrenocortical stem/progenitor cells: implications for adrenocortical carcinoma.
- SF-1, DAX-1, and acd: molecular determinants of adrenocortical growth and steroidogenesis.
- Adjuvant therapy in patients with adrenocortical carcinoma: a position of an international panel.
- Ectopic corticotropin-releasing hormone produced by a transfected cell line chronically activates the pituitary-Adrenal axis in transkaryotic rats.
- Pituitary corticotroph hyperplasia in rats implanted with a medullary Thyroid carcinoma cell line transfected with a corticotropin-releasing hormone complementary deox...
- Management of patients with Adrenal cancer: recommendations of an international consensus conference.
- Pituitary-specific and hormonally regulated gene expression directed by the rat proopiomelanocortin promoter in transgenic mice.
- Phosphorylation of the nuclear receptor SF-1 modulates cofactor recruitment: integration of hormone signaling in reproduction and stress.
- Identification of DNA elements cooperatively activating proopiomelanocortin gene expression in the pituitary glands of transgenic mice.
- Post-translational processing of proopiomelanocortin (POMC) in mouse pituitary melanotroph tumors induced by a POMC-simian virus 40 large T antigen transgene.
- Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression.
- Steroidogenic factor-1: its role in endocrine organ development and differentiation.
- [Quantification of pulmonary emphysema in multislice-CT using different software tools].
Schools
Conditions Treated
- Adrenal Incidentaloma
- Adrenal Insufficiency
- Adrenogenital Disorders
- Cushing's Syndrome
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Doctors Specialties
Accepted Insurances
Awards
- Elected Member
- The One Hundred, Inductee
- America's Top Doctors
- Edwin B. Astwood Award Lecture for Outstanding Research in Endocrinology
- America's Top Doctors for Cancer
- Inductee
- CMS Meaningful Use Stage 1 Certification
- Outstanding Reviewer Award
- Jerome Conn Award for Outstanding Research
- Millie Schembechler Endowed Chair of Adrenal Cancer
- Award Winner
- Merck Senior Fellow Award
- Research Award
- Outstanding Overall Teaching Contribution for Medical School-first Year, Nominee
- Outstanding Small Group Instructor for Medical School-second Year, Nominee
- Outstanding Clinical Preceptor for Medical School-second Year
- Outstanding Small Group Instructor for Medical School-first Year, Nominee
- Outstanding Achievement in Neuroscience Award
- Second Prize
- Third Prize
- Kidder Medal for Outstanding Senior Male
- Outstanding Senior in Department of Psychology
- Phi Beta Kappa Inductee
- Sigma Xi Inductee
- Wasson Award for Outstanding Scholar-Athlete
- Boulder Society Inductee
- Mortar Board Inductee
- Outstanding Contribution to Research in Psychology Award
Education
-
UCSF
-
Tufts University School of Medicine
Hospital
-
University of Michigan Hospitals and Health Centers
Drug Facts
| NPI NUMBER |
|
1871676791 |
| NPPES Provider LastName |
|
HAMMER |
| NPPES Provider FirstName |
|
GARY |
| NPPES Provider ZIPCode |
|
481095354 |
| NPPES Provider State |
|
MI |
| Specialty Description |
|
Endocrinology |
| Total Claim Count |
|
53.0 |
| Distinct Opioid Count |
|
0.0 |
| Opioid Claim Count |
|
0.0 |
| Percent Opioid Claims |
|
0.0 |
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Medicare Facts
| National Provider Identifier [NPI] |
1871676791 |
| Last Name Of The Provider |
HAMMER |
| First Name Of The Provider |
GARY |
| View All |
|
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