Associate Professor, Pathology and Immunology, Washington University School of Medicine
Anesthesiology
Dr. George J. Despotis, MD
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Dr. George J. Despotis practices Anesthesiology. He researched medicine at Saint Louis University School of Medicine. Saint Louis University School of Medicine is ranked 67 in research and 57 in primary care medicine George J. Despotis, MD is also a published doctor. He has 86 publication published. The most recent publication is: Economic impact of donor platelet count and platelet yield in apheresis products: relevance for emerging issues in platelet transfusion therapy. Doctor George J. Despotis, MD is registered with Medicare and accepts Medicare payments.
Publications
- Coronary artery bypass grafting in 2 thrombophilic patients with protein s deficiency.
- The occurrence of antibodies to heparin-platelet factor 4 in cardiac and thoracic surgical patients receiving desirudin or heparin for postoperative venous thrombosis ...
- Anticoagulation management during cardiopulmonary bypass: a survey of 54 North American institutions.
- The efficacy of photopheresis for bronchiolitis obliterans syndrome after lung transplantation.
- Plasma exchange for heparin-induced thrombocytopenia: is there enough evidence?
- Safety concerns related to use of unapproved needles for accessing implantable venous access devices.
- Transfusion and hemostasis in cardiac surgery.
- Transfusion risks and transfusion-related pro-inflammatory responses.
- Transfusion algorithms and how they apply to blood conservation: the high-risk cardiac surgical patient.
- B-type natriuretic peptide measured during transfusion-related acute lung injury.
- A phase III, double-blind, placebo-controlled, multicenter study on the efficacy of recombinant human antithrombin in heparin-resistant patients scheduled to undergo c...
- Preoperative use of enoxaparin increases the risk of postoperative bleeding and re-exploration in cardiac surgery patients.
- Guidelines and alternatives for neuraxial anesthesia and venous thromboembolism prophylaxis in major orthopedic surgery.
- The influence of crystalloid and colloid replacement solutions in acute normovolemic hemodilution: a preliminary survey of hemostatic markers.
- Monitoring hirudin anticoagulation in two patients undergoing cardiac surgery with a plasma-modified act method.
- Recombinant human transgenic antithrombin in cardiac surgery: a dose-finding study.
- Antithrombin III concentrate to treat heparin resistance in patients undergoing cardiac surgery.
- Transfusion medicine service policies for recombinant factor VIIa administration.
- Off-label use of recombinant factor VIIA concentrates after cardiac surgery.
- The Society of Thoracic Surgeons practice guideline series: aspirin and other antiplatelet agents during operative coronary revascularization (executive summary).
- The plasma supplemented modified activated clotting time for monitoring of heparinization during cardiopulmonary bypass: a pilot investigation.
- Perioperative blood transfusion and blood conservation in cardiac surgery: the Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists clinica...
- A review of transfusion risks and optimal management of perioperative bleeding with cardiac surgery.
- Heparin concentration-based anticoagulation for cardiac surgery fails to reliably predict heparin bolus dose requirements.
- Prediction and management of bleeding in cardiac surgery.
- A simple method of MDI administration in the intubated patient.
- Point-of-care testing. Cost issues and impact on hospital operations.
- Economic impact of donor platelet count and platelet yield in apheresis products: relevance for emerging issues in platelet transfusion therapy.
- Granulocyte collection efficiency and yield are enhanced by the use of a higher interface offset during apheresis of donors given granulocyte-colony-stimulating factor.
- Uses of antithrombin III concentrate in congenital and acquired deficiency states.
- Erythropoietin therapy in patients undergoing cardiac operations.
- A comparison between continuous infusion versus standard bolus administration of heparin based on monitoring in cardiac surgery.
- Monitoring of hemostasis in cardiac surgical patients: impact of point-of-care testing on blood loss and transfusion outcomes.
- Antithrombin III during cardiac surgery: effect on response of activated clotting time to heparin and relationship to markers of hemostatic activation.
- Relationship between leukocyte count and patient risk for excessive blood loss after cardiac surgery.
- Effects of platelets and white blood cells and antiplatelet agent C7E3 (Reopro) on a new test of PAF procoagulant activity of whole blood.
- Whole blood heparin concentration measurements by automated protamine titration agree with plasma anti-Xa measurements.
- Hemofiltration during cardiopulmonary bypass: the effect on anti-Xa and anti-IIa heparin activity.
- Multiple episodes of thrombosis with biventricular support devices with inadequate anticoagulation and evidence of accelerated intravascular coagulation.
- More effective suppression of hemostatic system activation in patients undergoing cardiac surgery by heparin dosing based on heparin blood concentrations rather than ACT.
- Evaluation of a new point-of-care test that measures PAF-mediated acceleration of coagulation in cardiac surgical patients.
- Recurrent thrombosis of biventricular-support devices associated with accelerated intravascular coagulation and increased heparin requirements.
- Factors associated with excessive postoperative blood loss and hemostatic transfusion requirements: a multivariate analysis in cardiac surgical patients.
- Evaluation of complete blood count results from a new, on-site hemocytometer compared with a laboratory-based hemocytometer.
- Aprotinin prolongs activated and nonactivated whole blood clotting time and potentiates the effect of heparin in vitro.
- Response of kaolin ACT to heparin: evaluation with an automated assay and higher heparin doses.
- Establishing practice guidelines for surgical blood management.
- On-site prothrombin time, activated partial thromboplastin time, and platelet count. A comparison between whole blood and laboratory assays with coagulation factor ana...
- Prospective evaluation and clinical utility of on-site monitoring of coagulation in patients undergoing cardiac operation.
- Profound systemic hypothermia protects the spinal cord in a primate model of spinal cord ischemia.
- The effect of an intraoperative treatment algorithm on physicians' transfusion practice in cardiac surgery.
- Comparison of activated coagulation time and whole blood heparin measurements with laboratory plasma anti-Xa heparin concentration in patients having cardiac operations.
- In vitro reversal of heparin effect with heparinase: evaluation with whole blood prothrombin time and activated partial thromboplastin time in cardiac surgical patients.
- Pressure gradient across the pulmonary artery anastomosis during lung transplantation.
- On the need for improved transfusion indicators in cardiac surgery.
- The impact of heparin concentration and activated clotting time monitoring on blood conservation. A prospective, randomized evaluation in patients undergoing cardiac o...
- Effect of heparin on whole blood activated partial thromboplastin time using a portable, whole blood coagulation monitor.
- Effect of aprotinin on activated clotting time, whole blood and plasma heparin measurements.
- Aprotinin prolongs whole blood activated partial thromboplastin time but not whole blood prothrombin time in patients undergoing cardiac surgery.
- Increased venous hemoglobin saturation during percutaneous right internal jugular vein cannulation in a patient with a mature right forearm arteriovenous hemodialysis ...
- A randomized trial comparing acute normovolemic hemodilution and preoperative autologous blood donation in total hip arthroplasty.
- Abciximab and bleeding during coronary surgery: results from the EPILOG and EPISTENT trials. Improve Long-term Outcome with abciximab GP IIb/IIIa blockade. Evaluation ...
- Management approaches to platelet-related microvascular bleeding in cardiothoracic surgery.
- The effect of epsilon-aminocaproic acid on HemoSTATUS and kaolin-activated clotting time measurements.
- Clinical evaluation of a new, point-of-care hemocytometer.
- Anticoagulation monitoring during cardiac surgery: a review of current and emerging techniques.
- Preoperative use of enoxaparin and tirofiban: possible association with increased bleeding postbypass.
- Adverse events in platelet apheresis donors: A multivariate analysis in a hospital-based program.
- A randomized trial of acute normovolemic hemodilution compared to preoperative autologous blood donation in total knee arthroplasty.
- Anticoagulation and anticoagulation reversal with cardiac surgery involving cardiopulmonary bypass: an update.
- Use of point-of-care test in identification of patients who can benefit from desmopressin during cardiac surgery: a randomised controlled trial.
- Optimal management of bleeding and transfusion in patients undergoing cardiac surgery.
- Effects of nicardipine and nitroglycerin on perioperative myocardial ischemia in patients undergoing coronary artery bypass surgery.
- Antiischemic effects of nicardipine and nitroglycerin after coronary artery bypass grafting.
- Future directions in utilization review: the role of transfusion algorithms.
- Mechanisms and attenuation of hemostatic activation during extracorporeal circulation.
- Warfarin therapy does not increase bleeding in patients undergoing heart transplantation.
- Occurrence of myocardial ischemia immediately after coronary revascularization using radial arterial conduits.
- The relationship between hirudin and activated clotting time: implications for patients with heparin-induced thrombocytopenia undergoing cardiac surgery.
- Transfusion medicine : support of patients undergoing cardiac surgery.
- Comparison of structured use of routine laboratory tests or near-patient assessment with clinical judgement in the management of bleeding after cardiac surgery.
- Recombinant human antithrombin III restores heparin responsiveness and decreases activation of coagulation in heparin-resistant patients during cardiopulmonary bypass.
- Use of activated recombinant factor VII for severe coagulopathy post ventricular assist device or orthotopic heart transplant.
- Should aprotinin continue to be used during cardiac surgery?
- 2011 update to the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists blood conservation clinical practice guidelines.
Schools
Saint Louis University School of Medicine
Evanston Hospital
Barnes Wash University
Northwestern
Nrthwstrn
Doctors Specialties
- Anesthesiology
Accepted Insurances
Education
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Washington University - Barnes-Jewish Hospital -
McGaw Medical Center of Northwestern University -
Saint Louis University School of Medicine
Hospital
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Barnes-Jewish Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1497771612 |
| Last Name Of The Provider | DESPOTIS |
| First Name Of The Provider | GEORGE |
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