Physician
General Surgery
Dr. Isaac W. Browder, MD
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Doctor Isaac W. Browder, MD is an expert in the field of General Surgery. He graduated from Tulane University School of Medicine. Doctor Isaac W. Browder, MD is a published physician as well. He has 51 publications published. The latest was: Zenker's diverticulum in the elderly: a neurologic etiology?
Publications
- Preconditioning with a TLR2 specific ligand increases resistance to cerebral ischemia/reperfusion injury.
- Activation of Toll-like receptor 4 signaling contributes to hippocampal neuronal death following global cerebral ischemia/reperfusion.
- Protection against myocardial ischemia/reperfusion injury in TLR4-deficient mice is mediated through a phosphoinositide 3-kinase-dependent mechanism.
- Glucan phosphate attenuates cardiac dysfunction and inhibits cardiac MIF expression and apoptosis in septic mice.
- The development of a novel mouse model of transient global cerebral ischemia.
- Attenuation of cardiac hypertrophy by inhibiting both mTOR and NFkappaB activation in vivo.
- Blocking the MyD88-dependent pathway protects the myocardium from ischemia/reperfusion injury in rat hearts.
- Overexpression of TLR2 and TLR4 susceptibility to serum deprivation-induced apoptosis in CHO cells.
- Blockade of MyD88 attenuates cardiac hypertrophy and decreases cardiac myocyte apoptosis in pressure overload-induced cardiac hypertrophy in vivo.
- At low serum glucan concentrations there is an inverse correlation between serum glucan and serum cytokine levels in ICU patients with infections.
- NF-kappaB activation is required for the development of cardiac hypertrophy in vivo.
- Murine models of intestinal anastomoses.
- Modulation of tissue Toll-like receptor 2 and 4 during the early phases of polymicrobial sepsis correlates with mortality.
- Primary aortogastric fistula after nissen fundoplication: a case report and review of pertinent literature.
- Human monocyte scavenger receptors are pattern recognition receptors for (1-->3)-beta-D-glucans.
- Glucan stimulates human dermal fibroblast collagen biosynthesis through a nuclear factor-1 dependent mechanism.
- Human vascular endothelial cells express pattern recognition receptors for fungal glucans which stimulates nuclear factor kappaB activation and interleukin 8 productio...
- Subclavian arterial injury associated with blunt trauma.
- Normal human fibroblasts express pattern recognition receptors for fungal (1-->3)-beta-D-glucans.
- Glucans exhibit weak antioxidant activity, but stimulate macrophage free radical activity.
- Early activation of IKKbeta during in vivo myocardial ischemia.
- Zenker's diverticulum in the elderly: a neurologic etiology?
- Receptor binding and internalization of a water-soluble (1-->3)-beta-D-glucan biologic response modifier in two monocyte/macrophage cell lines.
- NMR spectral analysis of a water-insoluble (1-->3)-beta-D-glucan isolated from Saccharomyces cerevisiae.
- Benefits of pulmonary artery catheter and transesophageal echocardiographic monitoring in laparoscopic cholecystectomy patients with cardiac disease.
- Comparison of the carbohydrate biological response modifiers Krestin, schizophyllan and glucan phosphate by aqueous size exclusion chromatography with in-line argon-io...
- Staple closure of the pancreas.
- Modification of post-operative C. albicans sepsis by glucan immunostimulation.
- Chronic calcific pancreatitis with pancreatic duct lithiasis due to stenosing papillitis.
- Immunotherapeutic modification of Escherichia coli--induced experimental peritonitis and bacteremia by glucan.
- Modification of diverse experimental immunosuppressive states by glucan.
- Protective effect of glucan-enhanced macrophage function in experimental pancreatitis.
- Use of absorbable collagen for hemostasis in general surgical patients.
- Hepatic trauma: to drain or not to drain?
- Early management of operative injuries of the extrahepatic biliary tract.
- Enhancement of interleukin-1 and interleukin-2 production by soluble glucan.
- In vitro tumoricidal activity of resting and glucan-activated Kupffer cells.
- Chemoimmunotherapy of experimental hepatic metastases.
- Soluble glucan and lymphokine-activated killer (LAK) cells in the therapy of experimental hepatic metastases.
- Effect of glucan on neutrophil dynamics and immune function in Escherichia coli peritonitis.
- Pre-clinical safety evaluation of soluble glucan.
- The role of complement in glucan-induced protection against septic shock.
- Macrophage activation decreases macrophage prostaglandin E2 release in experimental trauma.
- Computed tomography versus diagnostic peritoneal lavage: usefulness in immediate diagnosis of blunt abdominal trauma.
- Immunization against Trypanosoma cruzi: adjuvant effect of glucan.
- Disposition of ampiroxicam, a prodrug of piroxicam, in man.
- Isolation, physicochemical characterization and preclinical efficacy evaluation of soluble scleroglucan.
- A method for the solubilization of a (1----3)-beta-D-glucan isolated from Saccharomyces cerevisiae.
- Development, physicochemical characterization and preclinical efficacy evaluation of a water soluble glucan sulfate derived from Saccharomyces cerevisiae.
- Development of a water-soluble, sulfated (1-->3)-beta-D-glucan biological response modifier derived from Saccharomyces cerevisiae.
Schools
Tulane University of Louisiana
Tulane University
Charity Hospital
Doctors Specialties
- Critical Care Surgery
- General Surgery
Accepted Insurances
Education
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Louisiana State University -
Tulane University School of Medicine
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