Physician
Pathology
Dr. James R. Davie, MD
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James Davie is an expert in the field of Pathology. He went to medical school at University of Texas Southwestern Medical School. James Davie is also published. He has 101 publications published. The lastest publication: "SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors.'
Publications
- Histone H3 phosphorylation, immediate-early gene expression, and the nucleosomal response: a historical perspective (1) (1) This article is part of Special Issue en...
- Gene expression regulation through 14-3-3 interactions with histones and HDACs.
- Role of MSK1 in the malignant phenotype of Ras-transformed mouse fibroblasts.
- Selective association of peroxiredoxin 1 with genomic DNA and COX-2 upstream promoter elements in estrogen receptor negative breast cancer cells.
- Estrogen regulated expression of the p21 Waf1/Cip1 gene in estrogen receptor positive human breast cancer cells.
- Carcinoma ex spiradenoma/cylindroma confirmed by immunohistochemical and molecular loss-of-heterozygosity profiling.
- Epigenetic control.
- Increased genomic instability and altered chromosomal protein phosphorylation timing in HRAS-transformed mouse fibroblasts.
- Genomic instability and histone H3 phosphorylation induction by the Ras-mitogen activated protein kinase pathway in pancreatic cancer cells.
- Association of Sp3 and estrogen receptor alpha with the transcriptionally active trefoil factor 1 promoter in MCF-7 breast cancer cells.
- Mitotic partitioning of transcription factors.
- Chromatin organization and nuclear microenvironments in cancer cells.
- Nuclear microenvironments and cancer.
- Effects of the in vivo supply of butyrate on histone acetylation of cecum in piglets.
- Differential distribution of unmodified and phosphorylated histone deacetylase 2 in chromatin.
- Transcriptional silencing of the death gene BNIP3 by cooperative action of NF-kappaB and histone deacetylase 1 in ventricular myocytes.
- Estrogen receptor-alpha phosphorylated at Ser118 is present at the promoters of estrogen-regulated genes and is not altered due to HER-2 overexpression.
- Chromatin modification of the trefoil factor 1 gene in human breast cancer cells by the Ras/mitogen-activated protein kinase pathway.
- Phosphorylation of histones by tissue transglutaminase.
- Histone H4-K16 acetylation controls chromatin structure and protein interactions.
- Differential intranuclear organization of transcription factors Sp1 and Sp3.
- Histone modifications as a platform for cancer therapy.
- Estrogen regulation of trefoil factor 1 expression by estrogen receptor alpha and Sp proteins.
- Mitogen- and stress-activated protein kinase 1 activity and histone h3 phosphorylation in oncogene-transformed mouse fibroblasts.
- Elevated expression of the estrogen receptor prevents the down-regulation of p21Waf1/Cip1 in hormone dependent breast cancer cells.
- Chromatin immunoprecipitation: a tool for studying histone acetylation and transcription factor binding.
- Measurement of histone acetyltransferase and histone deacetylase activities and kinetics of histone acetylation.
- CHD1 associates with NCoR and histone deacetylase as well as with RNA splicing proteins.
- MSK1 and MSK2 mediate mitogen- and stress-induced phosphorylation of histone H3: a controversy resolved.
- The insulator binding protein CTCF associates with the nuclear matrix.
- Inhibition of histone deacetylase activity by butyrate.
- The transcriptional repressor Sp3 is associated with CK2-phosphorylated histone deacetylase 2.
- NAPP2, a peroxisomal membrane protein, is also a transcriptional corepressor.
- Isolation of transcriptionally active chromatin from human breast cancer cells using Sulfolink coupling gel chromatography.
- Characterization of stably transfected fusion protein GFP-estrogen receptor-alpha in MCF-7 human breast cancer cells.
- Ser-10 phosphorylation of histone H3 and immediate early gene expression in oncogene-transformed mouse fibroblasts.
- Suppression of DPYD expression in RKO cells via DNA methylation in the regulatory region of the DPYD promoter: a potentially important epigenetic mechanism regulating ...
- Activation and function of immediate-early genes in the nervous system.
- Nuclear organization and chromatin dynamics--Sp1, Sp3 and histone deacetylases.
- The role of Sp1 and Sp3 in normal and cancer cell biology.
- Current understanding and importance of histone phosphorylation in regulating chromatin biology.
- An integrated analysis of genes and pathways exhibiting metabolic differences between estrogen receptor positive breast cancer cells.
- Phosphorylated serine 28 of histone H3 is associated with destabilized nucleosomes in transcribed chromatin.
- Competitive inhibition of histone deacetylase activity by trichostatin A and butyrate.
- Biotin is not a natural histone modification.
- Nucleosomal response, immediate-early gene expression and cell transformation.
- H3 phosphorylation: dual role in mitosis and interphase.
- Promoter chromatin remodeling of immediate-early genes is mediated through H3 phosphorylation at either serine 28 or 10 by the MSK1 multi-protein complex.
- The role of Sp1 and Sp3 in the constitutive DPYD gene expression.
- Estrogen receptor-beta regulates psoriasin (S100A7) in human breast cancer.
- Sp1 and Sp3 foci distribution throughout mitosis.
- Abnormalities of chromatin in tumor cells.
- Stimulation of the Ras-MAPK pathway leads to independent phosphorylation of histone H3 on serine 10 and 28.
- The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling.
- Identification of a direct Dlx homeodomain target in the developing mouse forebrain and retina by optimization of chromatin immunoprecipitation.
- Gene regulation by Sp1 and Sp3.
- Histone H1(S)-3 phosphorylation in Ha-ras oncogene-transformed mouse fibroblasts.
- The many roles of the transcriptional regulator CTCF.
- The estrogen receptor: more than the average transcription factor.
- Inducible upregulation of oestrogen receptor-beta1 affects oestrogen and tamoxifen responsiveness in MCF7 human breast cancer cells.
- Histones of Chlamydomonas reinhardtii. Synthesis, acetylation, and methylation.
- Expression and characterization of branched-chain alpha-ketoacid dehydrogenase kinase from the rat. Is it a histidine-protein kinase?
- Increased phosphorylation of histone H1 in mouse fibroblasts transformed with oncogenes or constitutively active mitogen-activated protein kinase kinase.
- Molecular basis of maple syrup urine disease and stable correction by retroviral gene transfer.
- Differential compaction of transcriptionally competent and repressed chromatin reconstituted with histone H1 subtypes.
- Molecular and biochemical basis of intermediate maple syrup urine disease. Occurrence of homozygous G245R and F364C mutations at the E1 alpha locus of Hispanic-Mexican...
- In vitro reconstitution of the 24-meric E2 inner core of bovine mitochondrial branched-chain alpha-keto acid dehydrogenase complex: requirement for chaperonins GroEL a...
- Molecular chaperones: heat-shock proteins, foldases, and matchmakers.
- Inhibition of transcription selectively reduces the level of ubiquitinated histone H2B in chromatin.
- Histone acetyltransferase is associated with the nuclear matrix.
- Multiple functions of dynamic histone acetylation.
- Nuclear factor 1 is a component of the nuclear matrix.
- Transcription factor GATA-1-multiprotein complexes and chicken erythroid development.
- Fibroblasts transformed by combinations of ras, myc and mutant p53 exhibit increased phosphorylation of histone H1 that is independent of metastatic potential.
- The nuclear matrix and the regulation of chromatin organization and function.
- In situ footprinting of chicken histone H5 gene in mature and immature erythrocytes reveals common factor-binding sites.
- Properties of chicken erythrocyte histone deacetylase associated with the nuclear matrix.
- Analysis of human breast cancer nuclear proteins binding to the promoter elements of the c-myc gene.
- Novel DNase I hypersensitive sites in the 3'-flanking region of the human c-myc gene.
- Histone modifications, chromatin structure, and the nuclear matrix.
- Developmental changes in transcription factors associated with the nuclear matrix of chicken erythrocytes.
- Estrogen regulation of nuclear matrix-intermediate filament proteins in human breast cancer cells.
- Changes in the nuclear matrix of chicken erythrocytes that accompany maturation.
- Altered nuclear matrix protein profiles in oncogene-transformed mouse fibroblasts exhibiting high metastatic potential.
- Histone H1b phosphorylation is dependent upon ongoing transcription and replication in normal and ras-transformed mouse fibroblasts.
- A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression.
- Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression.
- Nuclear matrix proteins in well and poorly differentiated human breast cancer cell lines.
- Nuclear matrix, dynamic histone acetylation and transcriptionally active chromatin.
- Novel nuclear matrix protein HET binds to and influences activity of the HSP27 promoter in human breast cancer cells.
- Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family.
- Rapid deubiquitination of nucleosomal histones in human tumor cells caused by proteasome inhibitors and stress response inducers: effects on replication, transcription...
- Estrogen receptor diminishes DNA-binding activities of chicken GATA-1 and CACCC-binding proteins.
- Impaired assembly of E1 decarboxylase of the branched-chain alpha-ketoacid dehydrogenase complex in type IA maple syrup urine disease.
- Ubiquitination of histone H3 in elongating spermatids of rat testes.
- Histone acetylation is required to maintain the unfolded nucleosome structure associated with transcribing DNA.
- Covalent modifications of histones: expression from chromatin templates.
- Ras-associated nuclear structural change appears functionally significant and independent of the mitotic signaling pathway.
- In situ cross-linking by cisplatin of nuclear matrix-bound transcription factors to nuclear DNA of human breast cancer cells.
- SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors.
Schools
University of Texas Southwestern Medical Center At Dallas
Doctors Specialties
- Dermatopathology
- Pathology
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- Amerigroup (Wellpoint)
- Assurant Health
- CHAMPVA
- Cigna
- Commercial Insurance Company
- CoreSource
- Coventry Health Care
- First Health (Coventry Health Care) PPO
- Humana
- Mail Handlers Benefit Plan (MHBP)
- Medicaid
- Medicare MCR
- MultiPlan
- MVP Health Care
- Old Surety Life Insurance CompanyMedicare MCR
- Principal Life
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- United Healthcare
Education
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University of Pittsburgh Medical Center -
University of Texas Southwestern Medical School
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1609863612 |
| Last Name Of The Provider | DAVIE |
| First Name Of The Provider | JAMES |
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