Vice Chairman, Bascom Palmer Eye Institute and Associate Director, Sylvester Comprehensive Cancer Center, Miami, FL
Ophthalmology
Dr. James W. Harbour, MD
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James W. Harbour, MD works in the field of Ophthalmology. He studied medicine at Johns Hopkins University School of Medicine. Johns Hopkins University School of Medicine is a top medical university. Johns Hopkins University School of Medicine is ranked 3/29 in Research/PrimaryCare. He received 40 awards: "CMS Meaningful Use Stage 1 Certification", "Paul Henkind Memorial Award and Lecture", "America's Top Doctors", "Honor Award", "Shaler Richardson, MD Service to Medicine Award", "America's Top Doctors for Cancer", "Speaker of the Day", "Research Award", "Santen Prize for outstanding abstract from a Pan-American country", "Rosenthal Award", "Teacher of the Year Award in Research, DOVS", "Cogan Award", "Achievement Award", "Physician-Scientist Award", "Housestaff Research Award", "Alpha Omega Alpha Honor Medical Society", "Phi Beta Kappa National Honor Society", "Paul Ehrlich Clinical Research Award", "Phi Eta Sigma Academic Scholarship", "Phi Kappa Phi National Honor Society", "Phi Lambda Upsilon Chemistry Honor Society", "Beta Beta Beta Biology Honor Society", "Phi Eta Sigma Honor Society", "University Honors Program", "Academic Scholarships", "Dean's Honor Roll", "Senior Scientific Investigator Award", "Paul Henkind Memorial Award for outstanding retinal research", "Best Doctors in America", "Cogan Award for Top Ophthalmology Researcher Under 40", "Rosenthal Award for Top Retina Researcher Under 45", "Ocular Melanoma Foundation Research Award", "Senior Achievement Award", "Shaler Richardson Service to Medicine Award", "America's Top Ophthalmologists", "Best Doctors in St. Louis", "Top Doctors in Miami", "Who's Who in America", "Who's Who in Healthcare" and "Who's Who in Medical Sciences Education". James W. Harbour is a published doctor as well. He has 100 publications published. The latest was: Overview of RB gene mutations in patients with retinoblastoma. Implications for clinical genetic screening.
Publications
- Rapid regression of a subset of class 1 uveal melanomas after Iodine-125 plaque radiOtherapy suggests an inflammatory mechanism.
- GNAQ/11 Mutations in Uveal Melanoma: Is YAP the Key to Targeted Therapy?
- Recent developments in prognostic and predictive testing in uveal Melanoma.
- A Molecular Revolution in Uveal Melanoma: Implications for Patient Care and Targeted Therapy.
- Outcomes of Iodine-125 Plaque Brachytherapy for Uveal Melanoma With Intraoperative Ultrasonography and Supplemental Transpupillary ThermOtherapy.
- Combined PKC and MEK inhibition for treating metastatic uveal Melanoma.
- Genomic, prognostic, and cell-signaling advances in uveal Melanoma.
- Retinoblastoma protein prevents enteric nervous system defects and intestinal pseudo-obstruction.
- BAP1 deficiency causes loss of melanocytic cell identity in uveal Melanoma.
- Gene Expression Profiling versus TNM Classification.
- The DecisionDx-UM Gene Expression Profile Test Provides Risk Stratification and Individualized Patient Care in Uveal Melanoma.
- Impaired cholesterol efflux in senescent macrophages promotes age-related Macular degeneration.
- Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal Melanoma.
- A role for Jag2 in promoting uveal Melanoma dissemination and growth.
- Gene expressing profiling of iris Melanomas.
- High throughput mass spectrometry-based mutation profiling of primary uveal Melanoma.
- Notch Signaling Promotes Growth and Invasion in Uveal Melanoma.
- The genetics of uveal Melanoma: an emerging framework for targeted therapy.
- Histone deacetylase inhibitors induce growth arrest and differentiation in uveal Melanoma.
- A new mutation with staggering effects.
- ABCB1 identifies a subpopulation of uveal Melanoma cells with high metastatic propensity.
- Diagnostic testing and treatment choices in primary vitreoretinal lymphoma.
- p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoPtosis.
- Primary Vitreoretinal Lymphoma: A Report from an International Primary Central Nervous System Lymphoma Collaborative Group Symposium.
- Frequent mutation of BAP1 in metastasizing uveal Melanomas.
- Association between gene expression profile, proliferation and metastasis in uveal Melanoma.
- An accurate, clinically feasible multi-gene expression assay for predicting metastasis in uveal Melanoma.
- Review of 676 second primary tumors in patients with retinoblastoma: association between age at onset and tumor type.
- Loss of Id2 potentiates the tumorigenic effect of Rb inactivation in a mouse model of retinoblastoma.
- A transformation in ocular oncology: from megacenter to multicenter.
- Id2 deficiency promotes metastasis in a mouse model of ocular cancer.
- Molecular prognostic testing and individualized patient care in uveal Melanoma.
- Hepatic metastasis from uveal Melanoma: angiographic pattern predictive of survival after hepatic arterial chemoembolization.
- Oncogenic mutations in GNAQ occur early in uveal Melanoma.
- Emerging insights into the molecular pathogenesis of uveal Melanoma.
- Comment on "Lowpenetrant RB allele in small-cell cancer shows geldanamycin instability and discordant expression with mutant ras" by Park et al.
- A metastasis modifier locus on human chromosome 8p in uveal Melanoma identified by integrative genomic analysis.
- Micro-RNAs associated with metastasis in uveal Melanoma identified by multiplexed microarray profiling.
- Prognostic biomarkers in uveal Melanoma: evidence for a stem cell-like phenotype associated with metastasis.
- Correlation study of Benign cytomorphology and final clinical diagnosis.
- Hepatic arterial chemoembolization for management of metastatic Melanoma.
- Integrative genomic analysis of aneuploidy in uveal Melanoma.
- Tilting of radioactive plaques after initial accurate placement for treatment of uveal Melanoma.
- Treatment outcomes for primary intraocular lymphoma: implications for external beam radiOtherapy.
- Molecular prognostic testing in uveal Melanoma: has it finally come of age?
- Inhibiting angiogenesis in retinoblastoma.
- Loss of heterozygosity of chromosome 3 detected with single nucleotide polymorphisms is superior to monosomy 3 for predicting metastasis in uveal Melanoma.
- Transcriptomic versus chromosomal prognostic markers and clinical outcome in uveal Melanoma.
- Prognostic testing in uveal Melanoma by transcriptomic profiling of fine needle biopsy specimens.
- Rb at the interface between cell cycle and apoptotic decisions.
- Eye cancer: unique insights into oncogenesis: the Cogan Lecture.
- Functional gene expression analysis uncovers phenotypic switch in aggressive uveal Melanomas.
- Lipid exudation following plaque radiOtherapy for posterior uveal melanoma.
- Molecular pathobiology of uveal Melanoma.
- Association between microarray gene expression signature and extravascular matrix patterns in primary uveal Melanomas.
- Fine needle aspiration biopsy with adjunct immunohistochemistry in intraocular tumor management.
- DDEF1 is located in an amplified region of chromosome 8q and is overexpressed in uveal Melanoma.
- Functional analysis of the p53 pathway in response to ionizing radiation in uveal Melanoma.
- Loss of Rb-E2F repression results in caspase-8-mediated apoPtosis through inactivation of focal adhesion kinase.
- NBS1 expression as a prognostic marker in uveal Melanoma.
- Uveal Melanoma: genetic aspects.
- MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A.
- Gene expression profiling in uveal Melanoma reveals two molecular classes and predicts metastatic death.
- What is the best treatment for retinoblastoma?
- Cytologic diagnosis of intraocular lymphoma in vitreous aspirates.
- Photodynamic therapy for Choroidal metastasis from carcinoid tumor.
- For whom the bell tolls: susceptibility to common adult cancers in retinoblastoma survivors.
- Optical coherence tomography in the evaluation of retinal changes associated with suspicious choroidal melanocytic tumors.
- Association between posterior uveal melanoma and iris freckles, iris naevi, and Choroidal naevi.
- Association between Choroidal pigmentation and posterior uveal melanoma in a white population.
- Transpupillary thermOtherapy versus plaque radiOtherapy for suspected choroidal melanomas.
- Status of the NF1 tumor suppressor locus in uveal Melanoma.
- Pars plana vitrectomy in Eyes containing a treated posterior uveal melanoma.
- Ocular Melanoma: a review and the relationship to cutaneous Melanoma.
- Molecular genetics of uveal Melanoma.
- Distinct mechanisms for regulating the tumor suppressor and antiapoptotic functions of Rb.
- Rate of resolution of exudative retinal detachment after plaque radiOtherapy for uveal melanoma.
- Transducible peptide therapy for uveal Melanoma and retinoblastoma.
- Photodynamic therapy for circumscribed Choroidal hemangioma.
- Altered expression of Rb and p53 in uveal melanomas following plaque radiOtherapy.
- Risk factors for metastasis in retinoblastoma.
- Molecular basis of low-penetrance retinoblastoma.
- The molecular biology of retinoblastoma.
- Corepressors and retinoblastoma protein function.
- Chromatin remodeling and Rb activity.
- Deregulation of the Rb and p53 pathways in uveal Melanoma.
- The Rb/E2F pathway: expanding roles and emerging paradigms.
- Inactivation of retinoblastoma protein in uveal Melanoma by phosphorylation of sites in the COOH-terminal region.
- Rb function in cell-cycle regulation and apoPtosis.
- Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.
- Tumor suppressor genes in ophthalmology.
- Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1.
- Overview of RB gene mutations in patients with retinoblastoma. Implications for clinical genetic screening.
- Metastatic risk for distinct patterns of postirradiation local recurrence of posterior uveal Melanoma.
- Langerhans cell histiocytosis diagnosed by fine needle biopsy.
- Pars plana vitrectomy in the management of phakic and pseudophakic malignant glaucoma.
- Local carboplatin therapy in transgenic murine retinoblastoma.
- Vitrectomy for diabetic Macular edema associated with a thickened and taut posterior hyaloid membrane.
- Intraoperative echographic localization of iodine 125 episcleral radioactive plaques for posterior uveal Melanoma.
Schools
Johns Hopkins University School of Medicine
Greater Baltimore Mc
Wills Eye Hospital
Bascom Palmer Eye Institute
Procedures Preformed
- Canthotomy
- Destruction of Lesion of Retina and Choroid
- Drainage of Conjunctival Cyst
- Enucleation of Eye
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Conditions Treated
- Acute Endophthalmitis
- Age-Related Macular Degeneration
- Anterior Ischemic Optic Neuropathy
- Aphakia and Other Disorders of Lens
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Doctors Specialties
- Ophthalmology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
- Paul Henkind Memorial Award and Lecture
- America's Top Doctors
- Honor Award
- Shaler Richardson, MD Service to Medicine Award
- America's Top Doctors for Cancer
- Speaker of the Day
- Research Award
- Santen Prize for outstanding abstract from a Pan-American country
- Rosenthal Award
- Teacher of the Year Award in Research, DOVS
- Cogan Award
- Achievement Award
- Physician-Scientist Award
- Housestaff Research Award
- Alpha Omega Alpha Honor Medical Society
- Phi Beta Kappa National Honor Society
- Paul Ehrlich Clinical Research Award
- Phi Eta Sigma Academic Scholarship
- Phi Kappa Phi National Honor Society
- Phi Lambda Upsilon Chemistry Honor Society
- Beta Beta Beta Biology Honor Society
- Phi Eta Sigma Honor Society
- University Honors Program
- Academic Scholarships
- Dean's Honor Roll
- Senior Scientific Investigator Award
- Paul Henkind Memorial Award for outstanding retinal research
- Best Doctors in America
- Cogan Award for Top Ophthalmology Researcher Under 40
- Rosenthal Award for Top Retina Researcher Under 45
- Ocular Melanoma Foundation Research Award
- Senior Achievement Award
- Shaler Richardson Service to Medicine Award
- America's Top Ophthalmologists
- Best Doctors in St. Louis
- Top Doctors in Miami
- Who's Who in America
- Who's Who in Healthcare
- Who's Who in Medical Sciences Education
Education
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Washington University -
Wills Eye Hospital -
Johns Hopkins University School of Medicine
Hospital
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University of Miami Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1740288455 |
| Last Name Of The Provider | HARBOUR |
| First Name Of The Provider | JAMES |
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