Professor of Neuroscience, Professor of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine; Director, Center on Drug Addiction
Psychiatry
Dr. Jay M. Baraban, MD
Baraban practices Psychiatry. He studied medicine at Yale University School of Medicine. Yale University School of Medicine is a top medical university. Yale University School of Medicine has a rank of 7 in research and a 57 in primary care Jay M. Baraban, MD is a published physician. He has 101 publications published. The most current publication "Elevated extracellular calcium can prevent apoptosis via the calcium-sensing receptor."
Publications
- Rescuing dicer Defects via Inhibition of an Anti-dicing Nuclease.
- Narp knockout mice show normal reactivity to novelty but attenuated recovery from neophobia.
- Neuronal activity-regulated pentraxin expressed in medial prefrontal cortex neurons is not necessary for extinction of heroin self-administration.
- Role of medial prefrontal cortex Narp in the extinction of morphine conditioned place preference.
- Localized disruption of Narp in medial prefrontal cortex blocks reinforcer devaluation performance.
- Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1.
- Narp deletion blocks extinction of morphine place preference conditioning.
- Nicotine and Delta(9)-tetrahydrocannabinol withdrawal induce Narp in the central nucleus of the amygdala.
- Syx, a RhoA guanine exchange factor, is essential for angiogenesis in Vivo.
- Narp regulates long-term aversive effects of morphine withdrawal.
- A selective role for neuronal activity regulated pentraxin in the processing of sensory-specific incentive value.
- Opiate withdrawal induces Narp in the extended amygdala.
- ERK and p38 inhibit the expression of 4E-BP1 repressor of translation through induction of Egr-1.
- A dominant negative Egr inhibitor blocks nerve growth factor-induced neurite outgrowth by suppressing c-Jun activation: role of an Egr/c-Jun complex.
- L-buthionine sulfoximine potentiates the antitumor effect of 4-hydroperoxycyclophosphamide when administered locally in a rat glioma model.
- Autoradiographic distribution of forskolin and phorbol ester binding sites in the retina.
- Serotonergic and non-serotonergic neurons of the dorsal raphe: reciprocal changes in firing induced by peripheral nerve stimulation.
- Dendritic trafficking of brain-derived neurotrophic factor mRNA: regulation by translin-dependent and -independent mechanisms.
- The neuronal RhoA GEF, Tech, interacts with the synaptic multi-PDZ-domain-containing protein, MUPP1.
- The Translin/Trax RNA binding complex: clues to function in the nervous system.
- Nuclear translocation of the SRF co-activator MAL in cortical neurons: role of RhoA signalling.
- Tech: a RhoA GEF selectively expressed in hippocampal and cortical neurons.
- High affinity binding of the Translin/Trax complex to RNA does not require the presence of Y or H elements.
- Developmental expression of the SRF co-activator MAL in brain: role in regulating dendritic morphology.
- Prominent expression of Narp in central vestibular pathways: selective effect of labyrinth ablation.
- Prominent Narp expression in projection pathways and terminal fields.
- Trax is a component of the Translin-containing RNA binding complex.
- Selective expression of Narp, a secreted neuronal pentraxin, in orexin neurons.
- Blockade of NGF-induced neurite outgrowth by a dominant-negative inhibitor of the egr family of transcription regulatory factors.
- Sustained increase in Narp protein expression following repeated electroconvulsive seizure.
- Somatodendritic localization of Translin, a component of the Translin/Trax RNA binding complex.
- Functional comparison of Egr3 transcription factor isoforms: identification of an activation domain in the N-terminal segment absent from Egr3beta, a major isoform exp...
- Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-...
- Major Egr3 isoforms are generated via alternate translation start sites and differ in their abilities to activate transcription.
- Neuronal localization of the Adenomatous polyposis coli tumor suppressor protein.
- The EGR family of transcription-regulatory factors: progress at the interface of molecular and systems neuroscience.
- Inhibition versus induction of apoptosis by proteasome inhibitors depends on concentration.
- Elevated extracellular calcium can prevent apoptosis via the calcium-sensing receptor.
- Identification of translin and trax as components of the GS1 strand-specific DNA binding complex enriched in brain.
- Purification of a multipotent antideath activity from bovine liver and its identification as arginase: nitric oxide-independent inhibition of neuronal apoptosis.
- Sequential expression of Egr-1 and Egr-3 in hippocampal granule cells following electroconvulsive stimulation.
- Chronic ethanol administration decreases phosphorylation of cyclic AMP response element-binding protein in granule cells of rat cerebellum.
- Identification of a strand-specific Egr response element binding complex enriched in rat brain.
- Serum deprivation inhibits glutathione depletion-induced death in embryonic cortical neurons: evidence against oxidative stress as a final common mediator of neuronal ...
- Expression of the APC tumor suppressor protein in oligodendroglia.
- Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B.
- Rapid communication between neurons and astrocytes in primary cortical cultures.
- Identification of p42 mitogen-activated protein kinase as a tyrosine kinase substrate activated by maximal electroconvulsive shock in hippocampus.
- Rapid increases in peptide processing enzyme expression in hippocampal neurons.
- p42 mitogen-activated protein kinase in brain: prominent localization in neuronal cell bodies and dendrites.
- Activation of transcription factor genes in striatum by cocaine: role of both serotonin and dopamine systems.
- Thresholds for synaptic activation of transcription factors in hippocampus: correlation with long-term enhancement.
- High levels of expression of the tumor suppressor gene APC during development of the rat central nervous system.
- Differential regulation of calcium/calmodulin-dependent protein kinase II and p42 MAP kinase activity by synaptic transmission.
- Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione.
- Toward a crystal-clear view of lithium's site of action.
- Visualization of quantal synaptic transmission by dendritic calcium imaging.
- Oxidative stress induces apoptosis in embryonic cortical neurons.
- Genetic and activity-dependent regulation of zif268 expression: association with spatial learning.
- Activation of arc, a putative "effector" immediate early gene, by cocaine in rat brain.
- Activation of p42 mitogen-activated protein kinase by glutamate receptor stimulation in rat primary cortical cultures.
- Apoptotic death in an in vitro model of neuronal oxidative stress.
- Mapping miniature synaptic currents to single synapses using calcium imaging reveals heterogeneity in postsynaptic output.
- Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance.
- Cyclic AMP and synaptic activity-dependent phosphorylation of AMPA-preferring glutamate receptors.
- Noradrenergic innervation of serotonergic neurons in the dorsal raphe: demonstration by electron microscopic autoradiography.
- Prazosin selectively antagonizes neuronal responses mediated by alpha1-adrenoceptors in brain.
- Suppression of serotonergic neuronal firing by alpha-adrenoceptor antagonists: evidence against GABA mediation.
- Suppression of firing activity of 5-HT neurons in the dorsal raphe by alpha-adrenoceptor antagonists.
- Protein kinase C and tracheal contraction at low temperature.
- Potent agonist activity of DOB at 5-HT2 receptors in guinea pig trachea.
- Protein kinase C regulates smooth muscle tension in guinea-pig trachea and ileum.
- Heterogeneous localization of protein kinase C in rat brain: autoradiographic analysis of phorbol ester receptor binding.
- Convulsant-induced increase in transcription factor messenger RNAs in rat brain.
- Protein kinase C regulates ionic conductance in hippocampal pyramidal neurons: electrophysiological effects of phorbol esters.
- Cholinergic phosphatidylinositol modulation of inhibitory, G protein-linked neurotransmitter actions: electrophysiological studies in rat hippocampus.
- Go, a guanine nucleotide-binding protein: immunohistochemical localization in rat brain resembles distribution of second messenger systems.
- Characterization of inositol trisphosphate receptor binding in brain. Regulation by pH and calcium.
- Beyond receptors: multiple second-messenger systems in brain.
- Inositol trisphosphate receptor localization in brain: variable stoichiometry with protein kinase C.
- Mapping second messenger systems in the brain: differential localizations of adenylate cyclase and protein kinase C.
- Muscarinic agonists and phorbol esters increase tyrosine phosphorylation of a 40-kilodalton protein in hippocampal slices.
- Lithium dampens neurotransmitter response in smooth muscle: relevance to action in affective illness.
- Phorbol ester effects on neurotransmission: interaction with neurotransmitters and calcium in smooth muscle.
- Norepinephrine stimulation of adenylate cyclase potentiates protein kinase C action: electrophysiological studies in the dentate gyrus.
- The inositol trisphosphate receptor: a potpourri of second-messenger regulation.
- Neuronal muscarinic responses: role of protein kinase C.
- Lithium blocks a phosphoinositide-mediated cholinergic response in hippocampal slices.
- Solubilization, purification, and characterization of an inositol trisphosphate receptor.
- Demonstration of inositol 1,3,4,5-tetrakisphosphate receptor binding.
- Excitation of hippocampal neurons by stimulation of glutamate Qp receptors.
- Second messenger systems and psychoactive drug action: focus on the phosphoinositide system and lithium.
- Postreceptor mechanisms of small-bowel water and electrolyte transport.
- Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation.
- Inositol 1,4,5-trisphosphate receptor binding: autoradiographic localization in rat brain.
- Intrahippocampal injection of pertussis toxin blocks adenosine suppression of synaptic responses.
- Hallucinogenic drug interactions at human brain 5-HT2 receptors: implications for treating LSD-induced hallucinogenesis.
- Site of anticonvulsant action on sodium channels: autoradiographic and electrophysiological studies in rat brain.
- Synaptic regulation of transcription factor mRNA in the rat hippocampus.
- Rapid rise in transcription factor mRNAs in rat brain after electroshock-induced seizures.
Schools
Yale University
Doctors Specialties
- Psychiatry
Accepted Insurances
Education
-
Yale University School of Medicine
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