Physician
Family Medicine
Dr. John D. Gaston, MD
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John Gaston works in the field of Family Medicine. He graduated from University of Arkansas for Medical Sciences College of Medicine. University of Arkansas for Medical Sciences College of Medicine is ranked 83 in research and 35 in primary care medicine Dr. John D. Gaston is a published doctor. He has 46 papers published. The most current publication "T cell responses to heat-shock protein 60: differential responses by CD4+ T cell subsets according to their expression of CD45 isotypes." He accepts all Medicare patients.
Publications
- T lymphocyte lines isolated from atheromatous plaque contain cells capable of responding to Chlamydia antigens.
- Heat shock proteins as potential targets in the therapy of inflammatory arthritis.
- The recognition of HLA-B27 by human CD4(+) T lymphocytes.
- Interleukin-23: a central cytokine in the pathogenesis of spondylarthritis.
- Autoimmune T cell responses to seminal plasma in chronic pelvic pain syndrome (CPPS).
- The recognition of abnormal forms of HLA-B27 by CD4+ T cells.
- CD30:CD30 ligand interactions in the immune response.
- Immunological basis of Chlamydia induced reactive arthritis.
- Humoral immune response to the capsid components of recombinant adenoviruses: routes of immunization modulate virus-induced Ig subclass shifts.
- Dendritic cell: T-cell interactions in spondyloarthritis.
- Major histocompatibility complex class I-restricted alloreactive CD4+ T cells.
- Analysis of T cell subsets present in the peripheral blood and synovial fluid of reactive arthritis patients.
- Role of T-cells in the development of arthritis.
- Shigella induced reactive arthritis.
- Diagnosis of Takayasu''s arteritis by unexpected findings on abdominal CT scan.
- T cell recognition of a highly conserved epitope in heat shock protein 60: self-tolerance maintained by TCR distinguishing between asparagine and aspartic acid.
- Mucosal cell-mediated immunity to mycobacterial, enterobacterial and other microbial antigens in inflammatory bowel disease.
- Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression.
- Characterization of the humoral immune response to Chlamydia outer membrane protein 2 in chlamydial infection.
- Pathogenic role of gut inflammation in the spondyloarthropathies.
- Human gamma delta T-cell recognition of Yersinia enterocolitica.
- CD27 expression discriminates between regulatory and non-regulatory cells after expansion of human peripheral blood CD4+ CD25+ cells.
- T-cell response to mycobacterial proteins: a comparative study of tuberculous and control immunoblots of Mycobacterium tuberculosis and M. bovis BCG.
- Increased IL-4+ CD8+ T cells in peripheral blood and autoreactive CD8+ T cell lines of patients with inflammatory arthritis.
- Characterization of plasmacytoid dendritic cells in inflammatory arthritis synovial fluid.
- Generation of cytolytic T cells in individuals infected by Mycobacterium tuberculosis and vaccinated with BCG.
- Specific lysis of mycobacterial antigen-bearing macrophages by class II MHC-restricted polyclonal T cell lines in healthy donors or patients with tuberculosis.
- Recognition of the 60 kilodalton cysteine-rich outer membrane protein OMP2 by CD4(+) T cells from humans infected with Chlamydia trachomatis.
- T cell responses to heat-shock protein 60: differential responses by CD4+ T cell subsets according to their expression of CD45 isotypes.
- Restricted T cell receptor expression by human T cell clones specific for mycobacterial 65-kDa heat-shock protein: selective in vivo expansion of T cells bearing defin...
- Identification of 2 Chlamydia trachomatis antigens recognized by synovial fluid T cells from patients with Chlamydia induced reactive arthritis.
- Induction of abnormal Chlamydia trachomatis by exposure to interferon-gamma or amino acid deprivation and comparative antigenic analysis.
- Identification of Chlamydia trachomatis antigens recognized by human CD4+ T lymphocytes by screening an expression library.
- In vitro responses of human CD45R0brightRA- and CD45R0-RAbright T cell subsets and their relationship to memory and naive T cells.
- Human CD4+ cytolytic T cells kill antigen-pulsed target T cells by induction of apoptosis.
- Analysis of antigen reactive T-cells.
- Lysis of human macrophages by cytolytic CD4+ T cells fails to affect survival of intracellular Mycobacterium bovis-bacille Calmette-Guérin (BCG).
- Autoreactive human peripheral blood CD8+ T cells with a regulatory phenotype and function.
- CD4+ cytolytic T cells can destroy autologous and MHC-matched macrophages but fail to kill intracellular Mycobacterium bovis-BCG.
- HLA-B27 expression does not modulate intracellular Chlamydia trachomatis infection of cell lines.
- Effects of Chlamydia trachomatis infection on the expression of natural killer (NK) cell ligands and susceptibility to NK cell lysis.
- Chlamydia trachomatis-specific human CD8+ T cells show two patterns of antigen recognition.
- Uptake and processing of Chlamydia trachomatis by human dendritic cells.
- Infection of epithelial and dendritic cells by Chlamydia trachomatis results in IL-18 and IL-12 production, leading to interferon-gamma production by human natural kil...
- IFN-gamma regulates Fas ligand expression in human CD4+ T lymphocytes and controls their anti-mycobacterial cytotoxic functions.
Schools
University Of Arkansas For Medical Sciences College Of Medicine Uams University Of Arkansas For Medical Sciences
Eisenhower Army Med Center
Martin Army Community Hospital
University Of Arkansas
Procedures Preformed
- Physical Examination
- Wellness Physical Examination
Conditions Treated
- Allergies
- Asthma
- Depression
- Diabetes
- View All
Doctors Specialties
- Family Medicine
Accepted Insurances
- We do not accept health insurance
Education
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University of Arkansas for Medical Sciences College of Medicine
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