Physician
Cardiology
Dr. John L. Tan, MD
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John L. Tan, MD is an expert in the field of Cardiology. He received 1 awards: "CMS Meaningful Use Stage 1 Certification". John is also a published doctor. He has 101 publication published. The most recent publication is: OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis.
Publications
- GRIP1 is required for homeostatic regulation of AMPAR trafficking.
- Patient-reported quality of life and dyspnea among copd patients with nighttime and/or early morning symptoms.
- Assessment of nighttime and early morning symptoms among patients with chronic obstructive pulmonary disease.
- OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis.
- Prophylactic lidocaine use in acute myocardial infarction revisited in the thrombolytic era.
- Reduction in visceral slide is a good sign of underlying postoperative viscero-parietal adhesions in children.
- Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand.
- Endopyelotomy for pelvi-ureteric junction obstruction in children.
- A review of pediatric cases of urinary tract calculi.
- Clinical and laboratory features of invasive community-onset methicillin-resistant Staphylococcus aureus infection: a prospective case-control study.
- ATP-dependent potassium channel openers and preconditioning.
- Accuracy of various iron parameters in the prediction of iron deficiency in an acute care hospital.
- Intravenous sotalol for the termination of supraventricular tachycardia and atrial fibrillation and flutter: a multicenter, randomized, double-blind, placebo-controlle...
- Left superior vena cava, a remnant of embryological development.
- 1,25-Dihydroxyvitamin D3 increases type 1 interleukin-1 receptor expression in a murine T cell line.
- Interleukin 4, interferon-gamma, and prostaglandin E impact the osteoclastic cell-forming potential of murine bone marrow macrophages.
- Murine osteoblast interleukin 4 receptor expression: upregulation by 1,25 dihydroxyvitamin D3.
- Interleukin 4 increases type 5 acid phosphatase mRNA expression in murine bone marrow macrophages.
- Treatment of tachyarrhythmias during pregnancy and lactation.
- Short-coupled variant of torsade de pointes.
- Contribution of mechanical activity and electrical activity to cellular electrical uncoupling in ischemic rabbit papillary muscle.
- IL-1-induced murine osteoblast IL-6 production is mediated by the type 1 IL-1 receptor and is increased by 1,25 dihydroxyvitamin D3.
- Suppression of torsades de pointes by atropine.
- Preferences of cardiologists and clinical geneticists for the future organization of genetic care in hypertrophic cardiomyopathy: a survey.
- T wave alternans after sotalol: evidence for increased sensitivity to sotalol after conversion from atrial fibrillation to sinus rhythm.
- Biological pacing by gene and cell therapy.
- Electrophysiologic mechanisms of the long QT interval syndromes and torsade de pointes.
- Effects of adenosine A1-receptor activation on torsade de pointes in rabbits.
- Pregnancy and the risk of torsades de pointes in congenital long-QT syndrome.
- Ca2+-activated Cl- current reduces transmural electrical heterogeneity within the rabbit left ventricle.
- Adenosine induced ventricular arrhythmias in the emergency room.
- Gender disparities in torsade de pointes ventricular tachycardia.
- Family and population strategies for screening and counselling of inherited cardiac arrhythmias.
- Brugada syndrome: report of the second consensus conference.
- Fever-triggered ventricular arrhythmias in Brugada syndrome and type 2 long-QT syndrome.
- Long-term prognosis of patients diagnosed with Brugada syndrome: Results from the FINGER Brugada Syndrome Registry.
- R 56865 delays cellular electrical uncoupling in ischemic rabbit papillary muscle.
- Electrophysiologic and extracellular ionic changes during acute ischemia in failing and normal rabbit myocardium.
- Ischaemic preconditioning delays ischaemia induced cellular electrical uncoupling in rabbit myocardium by activation of ATP sensitive potassium channels.
- Role of Ca2+-activated Cl- current during proarrhythmic early afterdepolarizations in sheep and human ventricular myocytes.
- Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association.
- Novel Brugada syndrome-causing mutation in ion-conducting pore of cardiac Na+ channel does not affect ion selectivity properties.
- Cellular basis of sex disparities in human cardiac electrophysiology.
- A sodium-channel mutation causes isolated cardiac conduction disease.
- Long-term (subacute) potassium treatment in congenital HERG-related long QT syndrome (LQTS2).
- Active cascade screening in primary inherited arrhythmia syndromes: does it lead to prophylactic treatment?
- Early inflammatory response during the development of right ventricular heart failure in a rat model.
- Local depolarization abnormalities are the dominant pathophysiologic mechanism for type 1 electrocardiogram in brugada syndrome a study of electrocardiograms, vectorca...
- Duration of right ventricular contraction predicts the efficacy of bosentan treatment in patients with pulmonary hypertension.
- Intracellular calcium modulation of voltage-gated sodium channels in ventricular myocytes.
- Fever increases the risk for cardiac arrest in the Brugada syndrome.
- Impact of onsite or dispatched automated external defibrillator use on survival after out-of-hospital cardiac arrest.
- Differential changes in QTc duration during in-hospital haloperidol use.
- Genetic treatment of heart rhythm disorders-where do we stand?
- Right ventricular pacing improves haemodynamics in right ventricular failure from pressure overload: an open observational proof-of-principle study in patients with ch...
- Identification of a Sudden Cardiac Death Susceptibility Locus at 2q24.2 through Genome-Wide Association in European Ancestry Individuals.
- Activated human platelet products induce proarrhythmic effects in ventricular myocytes.
- Familial Brugada syndrome uncovered by hyperkalaemic diabetic ketoacidosis.
- Imaging of programmed cell death in arrhythmogenic right ventricle cardiomyopathy/dysplasia.
- Incidence, causes, and outcomes of out-of-hospital cardiac arrest in children. A comprehensive, prospective, population-based study in the Netherlands.
- Sex-deparities in cardiac electrophysiology: L-type Ca2+ current and the Na+-Ca2+ exchanger go hand in hand.
- Right ventricular failure following chronic pressure overload is associated with reduction in left ventricular mass evidence for atrophic remodeling.
- Facilitatory and inhibitory effects of SCN5A mutations on atrial fibrillation in Brugada syndrome.
- Diagnostic yield in sudden unexplained death and aborted cardiac arrest in the young: the experience of a tertiary referral center in The Netherlands.
- Genome-wide association study identifies a susceptibility locus at 21q21 for ventricular fibrillation in acute myocardial infarction.
- Liquid chromatographic assay with fluorescence detection to determine ajmaline in serum from patients with suspected Brugada syndrome.
- Assessment of inflammation in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia.
- Echocardiographic determinants of the clinical condition in patients with a systemic right ventricle.
- Cardiac sodium channelopathies.
- SCN5A mutations and the role of genetic background in the pathophysiology of Brugada syndrome.
- Mechanism of right precordial ST-segment elevation in structural heart disease: excitation failure by current-to-load mismatch.
- Cardiac ion channels in health and disease.
- Tubulin polymerization modifies cardiac sodium channel expression and gating.
- Right-to-left ventricular diastolic delay in chronic thromboembolic pulmonary hypertension is associated with activation delay and action potential prolongation in rig...
- Exercise-induced ECG changes in Brugada syndrome.
- Slow and discontinuous conduction conspire in Brugada syndrome: a right ventricular mapping and stimulation study.
- Nodoventricular accessory pathways in PRKAG2-dependent familial preexcitation syndrome reveal a disorder in cardiac development.
- Drugs and Brugada syndrome patients: review of the literature, recommendations, and an up-to-date website (www.brugadadrugs.org).
- Sudden unexpected death in epilepsy: risk factors and potential pathomechanisms.
- Bosentan as a bridge to pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension.
- Effects of muscarinic receptor stimulation on Ca2+ transient, cAMP production and pacemaker frequency of rabbit sinoatrial node cells.
- Myocyte necrosis underlies progressive myocardial dystrophy in mouse dsg2-related arrhythmogenic right ventricular cardiomyopathy.
- Serial noninvasive assessment of apoptosis during right ventricular disease progression in rats.
- Genetically determined differences in sodium current characteristics modulate conduction disease severity in mice with cardiac sodium channelopathy.
- Empiric quinidine therapy for asymptomatic Brugada syndrome: time for a prospective registry.
- Type of SCN5A mutation determines clinical severity and degree of conduction slowing in loss-of-function sodium channelopathies.
- Is sodium current present in human sinoatrial node cells?
- Are women with severely symptomatic brugada syndrome different from men?
- Fever-induced QTc prolongation and ventricular arrhythmias in individuals with type 2 congenital long QT syndrome.
- Engineering physiologically controlled pacemaker cells with lentiviral HCN4 gene transfer.
- Cardiac sodium channels and inherited electrophysiologic disorders: a pharmacogenetic overview.
- Diagnostic value of flecainide testing in unmasking SCN5A-related Brugada syndrome.
- Sodium channel variants in heart disease: expanding horizons.
- Gender disparities in cardiac cellular electrophysiology and arrhythmia susceptibility in human failing ventricular myocytes.
- Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome: a combined electrophysiological, genetic, histopathologic, and co...
- Role of sequence variations in the human ether-a-go-go-related gene (HERG, KCNH2) in the Brugada syndrome.
- Sudden unexplained death: heritability and diagnostic yield of cardiological and genetic examination in surviving relatives.
- Pathophysiological mechanisms of Brugada syndrome: depolarization disorder, repolarization disorder, or more?
- A mutation in the human cardiac sodium channel (E161K) contributes to sick sinus syndrome, conduction disease and Brugada syndrome in two families.
- Electrocardiographic evidence of ventricular repolarization remodelling during atrial fibrillation.
Schools
Stanford University School Of Medicine
Brigham and Women39s Hospital
Standford Medical School
Northwestern University
Procedures Preformed
- Cardiac Imaging
- Cardioversion, Elective
- Echocardiography
- Nuclear Cardiac Imaging
Doctors Specialties
- Cardiology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
Education
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Stanford University -
Brigham and Women's Hospital
Hospital
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Medical City Dallas Hospital
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