Physician

Pathology

Dr. John P. Tazelaar, MD

John P. Tazelaar practices Pathology. He graduated from University of Michigan Medical School. John Tazelaar is a published doctor as well. He has 28 publications published. The latest was: Adeno-associated virus as a vector for liver-directed gene therapy.

Publications

Adenoviral vector transfection into the pulmonary epithelium after cecal ligation and puncture in rats.
Intra-arterial delivery of a recombinant adenovirus does not increase gene transfer to tumor cells in a rat model of metastatic colorectal carcinoma.
Systemic IFN-beta gene therapy results in long-term survival in mice with established colorectal liver metastases.
Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors.
Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages.
Selective repopulation of normal mouse liver by hepatocytes transduced in vivo with recombinant adeno-associated virus.
Prolonged correction of hyperlipidemia in mice with familial hypercholesterolemia using an adeno-associated viral vector expressing very-low-density lipoprotein receptor.
In vivo selection of hepatocytes transduced with adeno-associated viral vectors.
Route of administration determines induction of T-cell-independent humoral responses to adeno-associated virus vectors.
Partial correction of murine hemophilia A with neo-antigenic murine factor VIII.
Readministration of adenovirus vector in nonhuman primate lungs by blockade of CD40-CD40 ligand interactions.
A phase I study of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator gene to a lung segment of individuals with cystic fibr...
Th2-dependent B cell responses in the absence of CD40-CD40 ligand interactions.
Adenoviral vector-mediated gene therapy in the mouse lung: no role of Fas-Fas ligand interactions for elimination of transgene expression in bronchioepithelial cells.
Wheat bran decreases aberrant crypt foci, preserves normal proliferation, and increases intraluminal butyrate levels in experimental colon cancer.
Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina.
Repeated administration of adenoviral vectors in lungs of human CD4 transgenic mice treated with a nondepleting CD4 antibody.
Adeno-associated virus as a vector for liver-directed gene therapy.
Direct intramuscular injection with recombinant AAV vectors results in sustained expression in a dog model of hemophilia.
Mother and son with deletion of 3p25-pter.
Regulated expression of erythropoietin from an AAV vector safely improves the anemia of beta-thalassemia in a mouse model.
Adenoviral transfer of HSP-70 into pulmonary epithelium ameliorates experimental acute respiratory distress syndrome.
Preexisting immunity to adenovirus in rhesus monkeys fails to prevent vector-induced toxicity.
A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency.
Prediction of MLH1 and MSH2 mutations in Lynch syndrome.
Detection of alpha 1-antitrypsin Z and S mutations by polymerase chain reaction-mediated site-directed mutagenesis.
Genetic testing in chronic pancreatitis.

Doctors Specialties

Molecular Genetic Pathology
Pathology

Accepted Insurances

Education

University of North Carolina Hospitals
University of Michigan Medical School

Helpful Reviews

Give Anonymous Review

Similar Doctors

	Dr. Wayne Y. Cai, MD This Doctor is OpenDoctor Recommended.
	Dr. Jeanette C. Dunn, MD This Doctor is OpenDoctor Recommended.
	Dr. Jeffrey A. Kant, MD This Doctor is OpenDoctor Recommended.
	Dr. Blima K. Mitre, MD
	Dr. Jan F. Silverman, MD This Doctor is OpenDoctor Recommended. This doctor has more publications
	Dr. Bevan Tandon, MD This Doctor is OpenDoctor Recommended.
	Dr. Ryan A. Collins, MD
	Dr. Somak Roy, MD This Doctor is OpenDoctor Recommended.
	Zaibo Li, MB This Doctor is OpenDoctor Recommended.