Physician

Pediatrics

Dr. Josefina D. Alonso, MD

Josefina Alonso works in the field of Pediatrics. Josefina Alonso is a published doctor as well. She has 59 publications published. The latest was: Role of COX-2-derived PGE2 on vascular stiffness and function in hypertension.

Publications

Role of COX-2-derived PGE2 on vascular stiffness and function in hypertension.
Toll-like receptor 4 contributes to vascular remodelling and endothelial dysfunction in angiotensin II-induced hypertension.
HuR mediates the synergistic effects of angiotensin II and IL-1Î² on vascular COX-2 expression and cell migration.
c-Src, ERK1/2 and Rho kinase mediate hydrogen peroxide-induced vascular contraction in hypertension: role of TXA2, NAD(P)H oxidase and mitochondria.
Pioglitazone reduces angiotensin II-induced COX-2 expression through inhibition of ROS production and ET-1 transcription in vascular cells from spontaneously hypertens...
A Potential Nanomedicine Consisting of Heparin-Loaded Polysaccharide Nanocarriers for the Treatment of Asthma.
A new drug nanocarrier consisting of polyarginine and hyaluronic acid.
Hyaluronic acid/chitosan-g-poly(ethylene glycol) nanoparticles for gene therapy: an application for pDNA and siRNA delivery.
Nanoparticles Based on PLGA:Poloxamer Blends for the Delivery of Proangiogenic Growth Factors.
Splanchnic Th(2) and Th(1) cytokine redistribution in microsurgical cholestatic rats.
Preparation of poly(lactic acid) (PLA) and poly(ethylene oxide) (PEO) nanoparticles as carriers for gene delivery.
Ocular tolerance to a topical formulation of hyaluronic acid and chitosan-based nanoparticles.
A prolonged, perplexing pyrexia.
Chitosan-alginate blended nanoparticles as carriers for the transmucosal delivery of macromolecules.
Atorvastatin prevents angiotensin II-induced vascular remodeling and oxidative stress.
Ionically crosslinked chitosan nanoparticles as gene delivery systems: effect of PEGylation degree on in vitro and in vivo gene transfer.
New generation of hybrid poly/oligosaccharide nanoparticles as carriers for the nasal delivery of macromolecules.
Hypertension increases contractile responses to hydrogen peroxide in resistance arteries through increased thromboxane A2, Ca2+, and superoxide anion levels.
Mucosal delivery of liposome-chitosan nanoparticle complexes.
Highly efficient system to deliver taxanes into tumor cells: docetaxel-loaded chitosan oligomer colloidal carriers.
Novel hyaluronic acid-chitosan nanoparticles for ocular gene therapy.
Vascular effects, angiotensin I-converting enzyme (ACE)-inhibitory activity, and antihypertensive properties of peptides derived from egg white.
Losartan reduces the increased participation of cyclooxygenase-2-derived products in vascular responses of hypertensive rats.
Alterations in structure and mechanics of resistance arteries from ouabain-induced hypertensive rats.
Chitosan nanoparticles as a potential drug delivery system for the ocular surface: toxicity, uptake mechanism and in vivo tolerance.
Development and brain delivery of chitosan-PEG nanoparticles functionalized with the monoclonal antibody OX26.
Design and characterization of a new drug nanocarrier made from solid-liquid lipid mixtures.
Application of NMR spectroscopy to the characterization of PEG-stabilized lipid nanoparticles.
Hypertension alters role of iNOS, COX-2, and oxidative stress in bradykinin relaxation impairment after LPS in rat cerebral arteries.
Chitosan nanoparticles as new ocular drug delivery systems: in vitro stability, in vivo fate, and cellular toxicity.
Impairment of fetal endothelium-dependent relaxation in a rat model of preeclampsia by chronic nitric oxide synthase inhibition.
Administration of N(omega)-L-arginine methyl ester (L-NAME) impairs endothelium-dependent relaxation in gravid but not nongravid rats.
Ouabain-induced hypertension is accompanied by increases in endothelial vasodilator factors.
Postnatal maturation in nitric oxide-induced pulmonary artery relaxation involving cyclooxygenase-1 activity.
Comparative uptake studies of bioadhesive and non-bioadhesive nanoparticles in human intestinal cell lines and rats: the effect of mucus on particle adsorption and tra...
Alterations of the nitric oxide pathway in cerebral arteries from spontaneously hypertensive rats.
Activation of BKCa channels by nitric oxide prevents coronary artery endothelial dysfunction in ouabain-induced hypertensive rats.
Ionically crosslinked chitosan/tripolyphosphate nanoparticles for oligonucleotide and plasmid DNA delivery.
Nanoparticles as protein and gene carriers to mucosal surfaces.
Preparation and in vitro evaluation of chitosan nanoparticles containing a caspase inhibitor.
PLGA:poloxamer blend micro- and nanoparticles as controlled release systems for synthetic proangiogenic factors.
Partial portal vein ligation plus thioacetamide: a method to obtain a new model of cirrhosis and chronic portal hypertension in the rat.
Mechanisms involved in the early increase of serotonin contraction evoked by endotoxin in rat middle cerebral arteries.
The potential of chitosan for the oral administration of peptides.
Chitosan-based nanostructures: a delivery platform for ocular therapeutics.
Nanoparticles for nasal vaccination.
Mast cell inhibition by ketotifen reduces splanchnic inflammatory response in a portal hypertension model in rats.
Surface-modified PLGA-based nanoparticles that can efficiently associate and deliver virus-like particles.
Memory formation requires p38MAPK activity in the rat hippocampus.
BDNF-triggered events in the rat hippocampus are required for both short- and long-term memory formation.
Aversive experiences are associated with a rapid and transient activation of ERKs in the rat hippocampus.
Development and characterization of PLGA nanospheres and nanocapsules containing xanthone and 3-methoxyxanthone.
Signaling mechanisms mediating BDNF modulation of memory formation in vivo in the hippocampus.
ERK1/2 activation is necessary for BDNF to increase dendritic spine density in hippocampal CA1 pyramidal neurons.
Early activation of extracellular signal-regulated kinase signaling pathway in the hippocampus is required for short-term memory formation of a fear-motivated learning.
Mitochondrial extracellular signal-regulated kinases 1/2 (ERK1/2) are modulated during brain development.
60-Day Chronic Exposure to Low Concentrations of HgCl2 Impairs Sperm Quality: Hormonal Imbalance and Oxidative Stress as Potential Routes for Reproductive Dysfunction ...
Small artery remodeling in obesity and insulin resistance.

Doctors Specialties

Pediatrics

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