Professor of Medicine Chief, Division of Gastroenterology and Hepatology
Gastroenterology
Dr. Joseph R. Pisegna, MD
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Joseph Pisegna practices Gastroenterology. He graduated from University of Miami Miller School of Medicine. University of Miami Miller School of Medicine is ranked 45 in research and 0 in primary care medicine He over the years received 5 awards: "Chair, Section of VIP, PACAP and Related Peptides", "Associate Editor", "Named New Investigator", "Alpha Omega Alpha" and "CMS Meaningful Use Stage 1 Certification". Joseph Pisegna is also a published MD. He has 88 paper published. The most recent paper is: The pituitary adenylate cyclase activating polypeptide type 1 receptor (PAC1-R) is expressed on gastric ECL cells: evidence by immunocytochemistry and RT-PCR. Dr. Joseph R. Pisegna accepts Medicare.
Publications
- PACAP intraperitoneal treatment suppresses appetite and food intake via PAC1 receptor in mice by inhibiting ghrelin and increasing GLP-1 and leptin.
- Inhibition of Vasoactive Intestinal Polypeptide (VIP) Induces Resistance to Dextran Sodium Sulfate (DSS)-Induced Colitis in Mice.
- High-protein diet selectively reduces fat mass and improves glucose tolerance in Western-type diet-induced obese rats.
- Adenoma detection rate is necessary but insufficient for distinguishing high versus low endoscopist performance.
- Ghrelin in neuroendocrine tumors.
- PAC1 deficiency in a murine model induces gastric mucosa hypertrophy and higher basal gastric acid output.
- Clinical trial report: Eradication of Helicobacter pylori reduces the risk for subsequent gastric cancer.
- Do COX-2 inhibitors reduce metachronous cancer development?
- PACAP induces signaling and stimulation of 5-hydroxytryptamine release and growth in neuroendocrine tumor cells.
- Effect of preoperative intravenous pantoprazole in elective-surgery patients: a pilot study.
- Duodenal bulb mucosa with hypertrophic gastric oxyntic heterotopia in patients with zollinger ellison syndrome.
- Is surveillance upper endoscopy indicated for gastric ulcers?
- Effects of esomeprazole on acid output in patients with Zollinger-Ellison syndrome or idiopathic gastric acid hypersecretion.
- Elevated serum ghrelin exerts an orexigenic effect that may maintain body mass index in patients with metastatic neuroendocrine tumors.
- Validation of a new endoscopic technique to assess acid output in Zollinger-Ellison syndrome.
- Neuroendocrine tumors express PAC1 receptors.
- Rabeprazole controls GERD symptoms in a patient for whom treatment with lansoprazole failed: first report of "cluster GERD.".
- Acid suppression in the perioperative period.
- PACAP regulation of secretion and proliferation of pure populations of gastric ECL cells.
- Reflux laryngitis in a patient with Zollinger Ellison syndrome and the role of epidermal growth factor.
- Differential coupling of the PAC1 SV1 splice variant on human colonic tumors to the activation of intracellular cAMP but not intracellular Ca2+ does not activate tumor...
- Treating patients with acute gastroIntestinal bleeding or rebleeding.
- Alcohol abuse and dependence: psychopathology, medical management and dental implications.
- Pharmacologic Treatment of Upper GastroIntestinal Bleeding.
- Maintenance oral pantoprazole therapy is effective for patients with Zollinger-Ellison syndrome and idiopathic hypersecretion.
- Pharmacology of acid suppression in the hospital setting: focus on proton pump inhibition.
- Proton pump activation in stimulated parietal cells is regulated by gastric acid secretory capacity: a human study.
- Paraesophageal Hernia repair and deep vein thrombosis.
- The novel use of an intravenous proton pump inhibitor in a patient with short bowel syndrome.
- PACAP-27 tyrosine phosphorylates mitogen activated protein kinase and increases VEGF mRNAs in human lung cancer cells.
- Model demonstrating respiratory mechanics for high school students.
- PACAP(6-38) is a PACAP receptor antagonist for breast cancer cells.
- Hepatic cytoreduction followed by a novel long-acting somatostatin analog: a paradigm for intractable neuroendocrine tumors metastatic to the liver.
- Impaired renal D(1)-like and D(2)-like dopamine receptor interaction in the spontaneously hypertensive rat.
- Review article: oesophageal complications and consequences of persistent gastro-oesophageal Reflux disease.
- Comparative efficacy of rabeprazole and pantoprazole in the control of nocturnal Acid output and intragastric acidity.
- Pituitary adenylate cyclase-activating polypeptide: a novel peptide with protean implications.
- Cyto-reduction of neuroendocrine tumours using Sandostatin LAR in combination with Infergen: results of a case series.
- The role of proton pump inhibitors in the treatment of Zollinger-Ellison syndrome.
- PAC1 and PACAP expression, signaling, and effect on the growth of HCT8, human colonic tumor cells.
- Expression of pituitary adenylate cyclase-activating polypeptide and PACAP type 1 receptor in the rat gastric and colonic myenteric neurons.
- GastroIntestinal dysfunction in mice with a targeted mutation in the gene encoding vasoactive Intestinal polypeptide: a model for the study of Intestinal ileus and Hir...
- Characterization of the pharmacology, signal transduction and internalization of the fluorescent PACAP ligand, fluor-PACAP, on NIH/3T3 cells expressing PAC1.
- Role of PACAP1 receptor in regulation of ECL cells and gastric acid secretion by pituitary adenylate cyclase activating peptide.
- Essential structural motif in the C-terminus of the PACAP type I receptor for signal transduction and internalization.
- Switching between intravenous and oral pantoprazole.
- The effect of Zollinger-Ellison syndrome and neuropeptide-secreting tumors on the stomach.
- Identification of an essential amino acid motif within the C terminus of the pituitary adenylate cyclase-activating polypeptide type I receptor that is critical for si...
- Salivary and gastric epidermal growth factor in patients with Zollinger-Ellison syndrome: its protective potential.
- Intravenous pantoprazole rapidly controls gastric acid hypersecretion in patients with Zollinger-Ellison syndrome.
- Oral and intravenous dosage forms of pantoprazole are equivalent in their ability to suppress gastric acid secretion in patients with Gastroesophageal reflux disease.
- PACAP type I receptor activation regulates ECL cells and gastric acid secretion.
- Inhibition of pentagastrin-induced gastric acid secretion by intravenous pantoprazole: a dose-response study.
- Adenocarcinoma of the colon with neuroendocrine features and secretory diarrhea.
- The pituitary adenylate cyclase activating polypeptide type 1 receptor (PAC1-R) is expressed on gastric ECL cells: evidence by immunocytochemistry and RT-PCR.
- International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactive Intestinal peptide and pituitary adenylate cyclase-activating polypeptide.
- PACAP hybrid: a new PACAP receptor antagonist.
- Ligand-induced internalization of cholecystokinin receptors. Demonstration of the importance of the carboxyl terminus for ligand-induced internalization of the rat cho...
- Differential signaling and immediate-early gene activation by four splice variants of the human pituitary adenylate cyclase-activating polypeptide receptor (hPACAP-R).
- Cloning and characterization of the signal transduction of four splice variants of the human pituitary adenylate cyclase activating polypeptide receptor. Evidence for ...
- Prospective study of efficacy and safety of lansoprazole in Zollinger-Ellison syndrome.
- An evaluation of human recombinant alpha interferon in patients with metastatic gastrinoma.
- Molecular cloning and functional expression of the pituitary adenylate cyclase-activating polypeptide type I receptor.
- Prospective study of the need for long-term antisecretory therapy in patients with Zollinger-Ellison syndrome following successful curative gastrinoma resection.
- Control of gastric acid hypersecretion in the management of patients with Zollinger-Ellison syndrome.
- Molecular cloning, functional expression and chromosomal localization of the human cholecystokinin type A receptor.
- A prospective study of intraoperative methods to diagnose and resect duodenal gastrinomas.
- Prospective comparative study of ability of MR imaging and other imaging modalities to localize tumors in patients with Zollinger-Ellison syndrome.
- Assessment and prediction of long-term cure in patients with the Zollinger-Ellison syndrome: the best approach.
- Distinguishing multiple CCK receptor subtypes. Studies with guinea pig chief cells and transfected human CCK receptors.
- Cholecystokinin receptor family. Molecular cloning, structure, and functional expression in rat, guinea pig, and human.
- Molecular cloning, functional expression, and chromosomal localization of the human cholecystokinin type A receptor.
- Fine needle aspiration cytology of submucosal nodules in patients with Zollinger-Ellison syndrome.
- Guinea pig gallbladder and pancreas possess identical CCK-A receptor subtypes: receptor cloning and expression.
- Chromosomal localization of the gastric and brain receptors for cholecystokinin (CCKAR and CCKBR) in human and mouse.
- Pituitary adenylate cyclase activating peptide receptors regulate the growth of non-small cell lung cancer cells.
- Tuberculous pancreatic abscess as a manifestation of AIDS.
- Effects of curative gastrinoma resection on gastric secretory function and antisecretory drug requirement in the Zollinger-Ellison syndrome.
- Brain and gastroIntestinal cholecystokinin receptor family: structure and functional expression.
- Endoscopic cure of the Zollinger-Ellison syndrome.
- Currently used doses of omeprazole in Zollinger-Ellison syndrome are too high.
- Molecular cloning of the human brain and gastric cholecystokinin receptor: structure, functional expression and chromosomal localization.
- Replacement of oral proton pump inhibitors with intravenous pantoprazole to effectively control gastric acid hypersecretion in patients with Zollinger-Ellison syndrome.
- GERD and its complications. The pathogenic relationship between symptoms and Disease progression.
- Three-year oral pantoprazole administration is effective for patients with Zollinger-Ellison syndrome and other hypersecretory conditions.
- Rabeprazole is superior to omeprazole for the inhibition of peptone meal-stimulated gastric acid secretion in Helicobacter pylori-negative subjects.
- Intravenous esomeprazole 40 mg vs. intravenous lansoprazole 30 mg for controlling intragastric acidity in healthy adults.
Schools
University of Miami School of Medicine
University MiamiJackson Meml Hospital
Georgetown UNih
Procedures Preformed
- Colonoscopy, Proctosigmoidoscopy, and Sigmoidoscopy
- Endoscopy (Esophagus, Stomach, Small Intestine)
Conditions Treated
- Abdominal Pain
- Barrett's Esophagus
- Benign Neoplasm of the Digestive System
- Diaphragmatic and-or Hiatal Hernia
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Doctors Specialties
- Gastroenterology
Accepted Insurances
Awards
- Chair, Section of VIP, PACAP and Related Peptides
- Associate Editor
- Named New Investigator
- Alpha Omega Alpha
- CMS Meaningful Use Stage 1 Certification
Education
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Georgetown University Hospital -
Jackson Memorial Hospital - Jackson Health System -
University of Miami Miller School of Medicine
Hospital
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Ronald Reagan UCLA Medical Center
Drug Facts
| NPI NUMBER | 1295755882 | |
| NPPES Provider LastName | PISEGNA | |
| NPPES Provider FirstName | JOSEPH | |
| NPPES Provider ZIPCode | 90095 | |
| NPPES Provider State | CA | |
| Specialty Description | Gastroenterology | |
| Total Claim Count | 38.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1295755882 |
| Last Name Of The Provider | PISEGNA |
| First Name Of The Provider | JOSEPH |
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