Associate Professor, Otolaryngology, Washington University in St. Louis School of Medicine
Otolaryngology (ENT)
Dr. Keiko Hirose, MD
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Keiko Hirose is an expert in the field of Otolaryngology (ENT). He graduated from Harvard Medical School. Harvard Medical School is a one of the best medicals schools. Harvard Medical School is ranked 1 in research and 12 in primary care medicine He over the years received 1 awards: "Fellow (FAAO-HNS)". Keiko Hirose is also a published physician. He has 101 paper published. The most recent paper is: Interleukin-15 may be responsible for early activation of intestinal intraepithelial lymphocytes after oral infection with Listeria monocytogenes in rats.
Publications
- Fractalkine Signaling Regulates Macrophage Recruitment into the Cochlea and Promotes the Survival of Spiral Ganglion Neurons after Selective Hair Cell Lesion.
- Systemic Lipopolysaccharide Compromises the Blood-Labyrinth Barrier and Increases Entry of Serum Fluorescein into the Perilymph.
- Systemic Lipopolysaccharide Induces Cochlear Inflammation and Exacerbates the Synergistic Ototoxicity of Kanamycin and Furosemide.
- Tolosa-Hunt syndrome masquerading as Gradenigo syndrome in a teenager.
- Production of pyridoxal phosphate by a mutant strain of Schizosaccharomyces pombe.
- PSK and OK-432-induced immunomodulation of inducible nitric oxide (NO) synthase gene expression in mouse peritoneal polymorphonuclear leukocytes and NO-mediated cytoto...
- NM23-H1 and NM23-H2 messenger RNA abundance in human hepatocellular carcinoma.
- Molecular cloning of a cDNA encoding the prepro-salmon gonadotropin-releasing hormone of the red seabream.
- Equation of state of the postperovskite phase synthesized from a natural (Mg,Fe)SiO3 orthopyroxene.
- Crystal structures of (Mg1-x,Fex)SiO3postperovskite at high pressures.
- Polyol pathway activity in streptozotocin-diabetic rat lens.
- Downregulation of intracellular nm23-H1 prevents cisplatin-induced DNA damage in oesophageal Cancer cells: possible association with Na(+), K(+)-ATPase.
- Cardiac sequelae of Kawasaki disease in Japan over 10 years.
- Inductive effect of Porphyromonas gingivalis fimbriae on differentiation of human monocytic tumor cell line U937.
- Caffeine inhibits Ca(2+)-mediated potentiation of inositol 1,4,5-trisphosphate-induced Ca2+ release in permeabilized vascular smooth muscle cells.
- Marked expression of glutathione S-transferase A4-4 detoxifying 4-hydroxy-2(E)-nonenal in the skin of rats irradiated by ultraviolet B-band light (UVB).
- Interleukin-15 may be responsible for early activation of intestinal intraepithelial lymphocytes after oral infection with Listeria monocytogenes in rats.
- Overexpression of IL-15 in vivo enhances protection against Mycobacterium bovis bacillus Calmette-Guérin infection via augmentation of NK and T cytotoxic 1 responses.
- Impaired IL-15 production associated with susceptibility of murine AIDS to mycobacterial infection.
- A candidate for Cancer gene therapy: MIP-1 alpha gene transfer to an adenocarcinoma cell line reduced tumorigenicity and induced protective immunity in immunocompetent...
- Purification and characterization of a novel Staphylococcus chromogenes exfoliative toxin.
- Radioactive decay speedup at T=5 K: electron-capture decay rate of (7)Be encapsulated in C(60).
- MgcRacGAP is involved in the control of growth and differentiation of hematopoietic cells.
- Structure and function of the intracellular portion of the mouse interleukin 1 receptor (type I). Determining the essential region for transducing signals to activate ...
- Chemokine gene transfection into tumour cells reduced tumorigenicity in nude mice in association with neutrophilic infiltration.
- The dynamin A ring complex: molecular organization and nucleotide-dependent conformational changes.
- Dynamics of noise-induced cellular injury and repair in the mouse cochlea.
- Coordination of kinesin's two heads studied with mutant heterodimers.
- Design and functional analysis of actomyosin motor domain chimera proteins.
- Pediatric cochlear implants.
- Intracapsular tonsillar reduction (partial tonsillectomy): reviving a historical procedure for obstructive Sleep disordered breathing in children.
- Alternate fast and slow stepping of a heterodimeric kinesin molecule.
- Lateral wall histopathology and endocochlear potential in the noise-damaged mouse cochlea.
- Electron microscopy of degenerative changes in the chick basilar papilla after gentamicin exposure.
- Murine autoimmune hearing loss mediated by CD4+ T cells specific for inner ear peptides.
- Starplasty: revisiting a pediatric tracheostomy technique.
- Safety and efficacy of powered intracapsular tonsillectomy in children: a multi-center retrospective case series.
- Expression of the carrier protein apolipoprotein D in the mouse inner ear.
- Mononuclear phagocytes migrate into the murine cochlea after acoustic trauma.
- Surgical management of cervical ganglioneuromas in children.
- A bidirectional kinesin motor in live Drosophila embryos.
- A role of the double-stranded RNA-binding protein PACT in mouse ear development and hearing.
- Large conformational changes in a kinesin motor catalyzed by interaction with microtubules.
- CC chemokine receptor 2 is protective against noise-induced hair cell death: studies in CX3CR1(+/GFP) mice.
- Orphan glutamate receptor delta1 subunit required for high-frequency hearing.
- Aminoglycoside ototoxicity.
- High-resolution structural analysis of the kinesin-microtubule complex by electron cryo-microscopy.
- A cool look at the structural changes in kinesin motor domains.
- Studying the structure of microtubules by electron microscopy.
- Repopulation of cochlear macrophages in murine hematopoietic progenitor cell chimeras: the role of CX3CR1.
- Nonsteroidal anti-inflammatory drugs and postoperative bleeding following adenotonsillectomy in pediatric patients.
- Single-headed mode of kinesin-5.
- Hearing loss and diabetes: you might not know what you're missing.
- Dynein pulls microtubules without rotating its stalk.
- Direct optical microscopic observation of the microtubule polymerization intermediate sheet structure in the presence of gas7.
- Dominant negative mutant actins identified in flightless Drosophila can be classified into three classes.
- Expression of fractalkine receptor CX3CR1 on cochlear macrophages influences survival of hair cells following ototoxic injury.
- Comparative analysis of combination kanamycin-furosemide versus kanamycin alone in the mouse cochlea.
- A novel system for expressing toxic actin mutants in Dictyostelium and purification and characterization of a dominant lethal yeast actin mutant.
- Relationship between the Structures of Taxane Derivatives and Their Microtubule Polymerization Activity.
- Re-examination of the polarity of microtubules and sheets decorated with kinesin motor domain.
- Reactive oxygen species in chick hair cells after gentamicin exposure in vitro.
- Congruent docking of dimeric kinesin and ncd into three-dimensional electron cryomicroscopy maps of microtubule-motor ADP complexes.
- Structural comparison of dimeric Eg5, Neurospora kinesin (Nkin) and Ncd head-Nkin neck chimera with conventional kinesin.
- Nucleotide-dependent structural changes in dimeric NCD molecules complexed to microtubules.
- Three-dimensional cryoelectron microscopy of 16-protofilament microtubules: structure, polarity, and interaction with motor proteins.
- 3D electron microscopy of the interaction of kinesin with tubulin.
- cDNA cloning of a murine homologue of Drosophila single-minded, its mRNA expression in mouse development, and chromosome localization.
- Three-dimensional cryoelectron microscopy of dimeric kinesin and ncd motor domains on microtubules.
- Dynamic studies of ototoxicity in mature avian auditory epithelium.
- Nucleotide-dependent angular change in kinesin motor domain bound to tubulin.
- Three-dimensional structure of motor molecules.
- A novel approach for purification of recombinant proteins using the dextran-binding domain.
- The conformational cycle of kinesin.
- Interleukin-15 production at the early stage after oral infection with Listeria monocytogenes in mice.
- Molecular cloning of polymorphic markers on RLGS gel using the spot target cloning method.
- The structure of microtubule-motor complexes.
- Identification of an imprinted U2af binding protein related sequence on mouse chromosome 11 using the RLGS method.
- cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclea...
- The reeler gene encodes a protein with an EGF-like motif expressed by pioneer neurons.
- 85Kr measurement system for continuous monitoring at the Meteorological Research Institute, Japan.
- Structural change of crossbridges of rabbit skeletal muscle during isometric contraction.
- Comparison of DNA methylation patterns among mouse cell lines by restriction landmark genomic scanning.
- Heterogeneity among human nasopharyngeal carcinoma cell lines for inflammatory cytokines mRNA expression levels.
- Stac, a novel neuron-specific protein with cysteine-rich and SH3 domains.
- Utility of laboratory testing in autoimmune inner ear disease.
- Direct detection and isolation of restriction landmark genomic scanning (RLGS) spot DNA markers tightly linked to a specific trait by using the RLGS spot-bombing method.
- Ca(2+)-sensor region of IP(3) receptor controls intracellular Ca(2+) signaling.
- Bacteroides (Porphyromonas) gingivalis fimbriae activate mouse peritoneal macrophages and induce gene expression and production of interleukin-1.
- Conformations of crossbridges in contracting skeletal muscle.
- Role of MgcRacGAP/Cyk4 as a regulator of the small GTPase Rho family in cytokinesis and cell differentiation.
- Endogenous IL-15 might be responsible for early protection by natural killer cells against infection with an avirulent strain of Salmonella choleraesuis in mice.
- [Epidemiology of lymphoid and hematopoietic malignancies in Japan].
- Embryonic lethality and abnormal cardiac myocytes in mice lacking ryanodine receptor type 2.
- MgcRacGAP is involved in cytokinesis through associating with mitotic spindle and midbody.
- Mapping of heme-binding domains in soluble guanylyl cyclase beta1 subunit.
- Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
- The efficacy of intra-articular analgesia after total knee arthroplasty in patients with rheumatoid arthritis and in patients with osteoarthritis.
- Effects of needle-arthroscopic lavage with different volumes of fluid on knee synovitis in rheumatoid arthritis.
- Phase transition of FeO and stratification in Earth's outer core.
Schools
Harvard Medical School
University of Washington
Children39s Hospital Boston
Mass Ee Infirm
Procedures Preformed
- Laryngoscopy - Laryngotomy - Laryngectomy - Pharyngolaryngectomy - Pharyngectomy
- Laryngoscopy and Laryngotomy
- Tracheal Surgery
Conditions Treated
- ENT Cancer
- Sleep Apnea
- Thyroid Cancer
Doctors Specialties
- Ear, Nose, and Throat
- Otolaryngology (ENT)
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- Anthem Blue Cross Blue Shield PPO
- Assurant Health
- Blue Card PPO
- Blue Cross Blue Shield of Illinois PPO
- Cigna HMO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- LocalPlus
- Open Access Plus
- Cofinity PPO
- CoreSource
- Coventry Health Care
- Coventry Health Care of Illinois PPO
- Health and Life PPO
- Platinum PPO
- Coventry Health Care of Missouri PPO
- Golden Rule
- HealthLink PPO
- Homestate Health Plan
- Choice Care PPO
- Medicaid
- Medicare MCR
- Molina
- MultiPlan PPO
- PHCS Network PPO
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- United Healthcare
Awards
- Fellow (FAAO-HNS)
Education
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University of Washington -
Harvard Medical School
Hospital
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Barnes-Jewish Hospital -
St. Louis Children's Hospital
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