Assistant Professor in Medicine Tufts Medical Center
Gastroenterology
Dr. Kenneth E. Hung, MD
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Doctor Kenneth E. Hung, MD is an expert in the field of Gastroenterology. He graduated from Johns Hopkins University School of Medicine. Johns Hopkins University School of Medicine is one of the top medical schools in the US. Johns Hopkins University School of Medicine is ranked 3 in research and 29 in primary care medicine Doctor Kenneth E. Hung, MD is also a published MD. He has 25 publication published. The most recent publication is: Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine... Doctor Kenneth E. Hung, MD accepts all Medicare patients.
Publications
- Colon-specific tumorigenesis in mice driven by Cre-mediated inactivation of Apc and activation of mutant Kras.
- Cross-species analysis of genetically engineered mouse models of MAPK driven Colorectal cancer identifies hallmarks of human disease.
- Combination PI3K/MEK inhibition promotes tumor apoptosis and regression in PIK3CA wild-type, KRAS mutant Colorectal cancer.
- mTOR Inhibition Specifically Sensitizes Colorectal Cancers with KRAS or BRAF Mutations to BCL-2/BCL-XL Inhibition by Suppressing MCL-1.
- Concomitant BRAF and PI3K/mTOR Blockade Is Required for Effective Treatment of BRAFV600E Colorectal Cancer.
- Development of a Colon Cancer GEMM-Derived Orthotopic Transplant Model for Drug Discovery and Validation.
- Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models.
- Priceless GEMMs: genetically engineered mouse models for Colorectal cancer drug development.
- EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant Colorectal cancers to RAF inhibition with vemurafenib.
- The Dual PI3K/mTOR Inhibitor NVP-BEZ235 Induces Tumor Regression in a Genetically Engineered Mouse Model of PIK3CA Wild-Type Colorectal Cancer.
- Proteomic approaches to Cancer biomarkers.
- Cathepsin B expression and survival in colon Cancer: implications for molecular detection of neoplasia.
- In vivo wide-area cellular imaging by side-view endomicroscopy.
- Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment.
- Comprehensive proteome analysis of an Apc mouse model uncovers proteins associated with Intestinal tumorigenesis.
- New road map through the land of IBD.
- Mass spectrometry-based study of the plasma proteome in a mouse Intestinal tumor model.
- Colorectal cancer screening: today and tomorrow.
- New insights into the molecular pathogenesis of Colorectal cancer.
- Detection of proximal adenomatous polyps with screening sigmoidoscopy: a Systematic review and meta-analysis of screening colonoscopy.
- Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant Colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine...
- Overview of genetically engineered mouse models of Colorectal carcinoma to enable translational biology and drug development.
- A mouse plasma peptide atlas as a resource for Disease proteomics.
- Low-volume, high-throughput sandwich immunoassays for profiling plasma proteins in mice: identification of early-stage Systemic inflammation in a mouse model of intest...
Schools
Johns Hopkins University School of Medicine
Hospital Of University Penn
Massachusetts General Hospital
Procedures Preformed
- Colonoscopy, Proctosigmoidoscopy, and Sigmoidoscopy
- Endoscopy (Esophagus, Stomach, Small Intestine)
Conditions Treated
- Abdominal Pain
- Anemia
- Barrett's Esophagus
- Benign Neoplasm of the Digestive System
- View All
Doctors Specialties
- Gastroenterology
Accepted Insurances
Education
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Massachusetts General Hospital -
University of Pennsylvania Health System -
Johns Hopkins University School of Medicine -
Johns Hopkins School of Medicine -
Harvard College
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