Assistant Professor, Pediatrics, University of Colorado School of Medicine
Pediatric Rheumatology
Dr. Leonard L. Dragone, MD
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Leonard Dragone practices Pediatric Rheumatology. He studied medicine at University of Rochester School of Medicine and Dentistry. He has 3 awards "Regional Top Doctor", "Fellow" and "Fellow (FACR)". Leonard Dragone is a published physician as well. He has 11 publications published. The latest was: Regulation of T cell receptor complex-mediated signaling by ubiquitin and ubiquitin-like modifications.
Publications
- SLAP deficiency decreases dsDNA autoantibody production.
- SLAP deficiency increases TCR avidity leading to altered repertoire and negative selection of cognate antigen-specific CD8+ T cells.
- The Src-like adaptor protein regulates GM-CSFR signaling and monocytic dendritic cell maturation.
- SLAP deficiency enhances number and function of regulatory T cells preventing chronic autoimmune Arthritis in SKG mice.
- Src-like adaptor protein (SLAP) regulates B cell receptor levels in a c-Cbl-dependent manner.
- Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex.
- SRC-like adaptor protein regulates B cell development and function.
- Src-like adaptor protein down-regulates T cell receptor (TCR)-CD3 expression by targeting TCRzeta for degradation.
- Regulation of T cell receptor complex-mediated signaling by ubiquitin and ubiquitin-like modifications.
- The Discovery of a Reciprocal Relationship between Tyrosine-Kinase Signaling and Cullin Neddylation.
Schools
University Of Rochester School Of Medicine and Dentistry
University Of California San Francisco Program
Conditions Treated
- Arthritis
- Dermatomyositis
- Fibromyalgia
- Juvenile Chronic Arthritis
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Doctors Specialties
- Pediatric Rheumatology
Accepted Insurances
Awards
- Regional Top Doctor
- Fellow
- Fellow (FACR)
Education
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UCSF -
University of Rochester School of Medicine and Dentistry
Hospital
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National Jewish Health