Professor, Pathology, University of Virginia School of Medicine

Pathology

Dr. Mani S. Mahadevan, MD

Dr. Mani S. Mahadevan works in the field of Pathology. Dr. Mani S. Mahadevan is a published MD. He has 40 publications published. The most current publication "Structure and genomic sequence of the myotonic dystrophy (DM kinase) gene." He accepts Medicare payments and is listed with Medicare.gov.

Publications

Multiple cutaneous lymphoproliferative disorders showing a retained tumor clone by T-cell receptor gene rearrangement analysis: a case series of four patients and revi...
TWEAK/Fn14, a pathway and novel therapeutic target in myotonic dystrophy.
NKX2-5, a modifier of skeletal muscle pathology due to RNA toxicity.
Evaluating the effects of CELF1 deficiency in a mouse model of RNA toxicity.
Myotonic dystrophy: is a narrow focus obscuring the rest of the field?
Myotonic muscular dystrophy, RNA toxicity, and the brain: trouble making the connection?
Therapeutics development in myotonic dystrophy type 1.
Genetics. Exposing a DUX tale.
The effect of myotonic dystrophy transcript levels and location on muscle differentiation.
Detection of immunoglobulin heavy chain gene rearrangements in classic hodgkin lymphoma using commercially available BIOMED-2 primers.
RNA toxicity in myotonic muscular dystrophy induces NKX2-5 expression.
Reversible model of RNA toxicity and cardiac conduction defects in myotonic dystrophy.
Factor V null mutation affecting the Roche LightCycler factor V Leiden assay.
Genotype-phenotype correlations: assessing the influence of sequence variants on the clinical phenotype.
Myogenic defects in myotonic dystrophy.
Mutant DMPK 3'-UTR transcripts disrupt C2C12 myogenic differentiation by compromising MyoD.
TWEAK Regulates Muscle Functions in a Mouse Model of RNA Toxicity.
Development of an AP-FRET Based Analysis for Characterizing RNA-Protein Interactions in Myotonic Dystrophy (DM1).
Age of Onset of RNA Toxicity Influences Phenotypic Severity: Evidence from an Inducible Mouse Model of Myotonic Dystrophy (DM1).
Analysis of trinucleotide repeats in myotonic dystrophy.
Characterization and polymerase chain reaction (PCR) detection of an Alu deletion polymorphism in total linkage disequilibrium with myotonic dystrophy.
Cloning of the essential myotonic dystrophy region and mapping of the putative defect.
Physical mapping and cloning of the proximal segment of the myotonic dystrophy gene region.
Overexpression of MBNL1 fetal isoforms and modified splicing of Tau in the DM1 brain: two individual consequences of CUG trinucleotide repeats.
SMA genes: deleted and duplicated.
Changes in free thyroxin (FT4) values of Clinical Assays Gammacoat two-step assay.
Evaluation of four commercially available assays for free thyroxin.
Myotonic dystrophy mutation: an unstable CTG repeat in the 3' untranslated region of the gene.
Intergenerational stability of the myotonic dystrophy protomutation.
The correlation of age of onset with CTG trinucleotide repeat amplification in myotonic dystrophy.
High resolution genetic analysis suggests one ancestral predisposing haplotype for the origin of the myotonic dystrophy mutation.
Structure and genomic sequence of the myotonic dystrophy (DM kinase) gene.
Reduction in size of the myotonic dystrophy trinucleotide repeat mutation during transmission.
Characterization of the myotonic dystrophy region predicts multiple protein isoform-encoding mRNAs.
Effect of the myotonic dystrophy (DM) mutation on mRNA levels of the DM gene.
Myotonic dystrophy: the role of the CUG triplet repeats in splicing of a novel DMPK exon and altered cytoplasmic DMPK mRNA isoform ratios.
The myotonic dystrophy expanded CUG repeat tract is necessary but not sufficient to disrupt C2C12 myoblast differentiation.
Cis and trans effects of the myotonic dystrophy (DM) mutation in a cell culture model.
Woodchuck post-transcriptional element induces nuclear export of myotonic dystrophy 3'' untranslated region transcripts.

Schools

University Of Ottawa Faculty Of Med Ottawa On Canada
Victoria Hospital
University Of Ottawa

Doctors Specialties

Pathology

Accepted Insurances

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Medicare Facts

National Provider Identifier [NPI]	1609996057
Last Name Of The Provider	MAHADEVAN
First Name Of The Provider	MANI
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