Physician
Gastroenterology
Dr. Mark I. Avigan, MD
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Mark Avigan works in the field of Gastroenterology. He graduated from Wayne State University School of Medicine. Wayne State University School of Medicine is ranked 63 in research and 85 in primary care medicine Mark Avigan is also a published MD. He has 52 publication published. The most recent publication is: FUSE-binding protein is developmentally regulated and is highly expressed in mouse and chicken embryonic brain.
Publications
- The clinical liver safety assessment best practices workshop: rationale, goals, accomplishments and the future.
- Liver safety assessment: required data elements and best practices for data collection and standardization in clinical trials.
- DILI and Drug Development: A Regulatory Perspective.
- Profiling Cumulative Proportional Reporting Ratios of Drug-Induced Liver Injury in the FDA Adverse Event Reporting System (FAERS) Database.
- Validity of diagnostic codes to identify cases of severe acute liver injury in the U.S. Food and Drug Administration's Mini-Sentinel Distributed Database.
- Spontaneous reports of seizure in association with leuprolide (lupron depot), goserelin (zoladex implant), and naferelin (synarel nasal spray).
- Needs for an expanded ontology-based classification of adverse drug reactions and related mechanisms.
- Using controlled clinical trials to learn more about acute drug-induced liver injury.
- Studies on the compartmentation of lipid in adipose cells. II. Cholesterol accumulation and distribution in adipose tissue components.
- GATA-6 stimulates a cell line-specific activation element in the human lactase promoter.
- Immune effects of alpha-interferon in chronic liver disease.
- Randomized trial of chlorambucil for primary biliary cirrhosis.
- Morphologic features of the liver in abetalipoproteinemia.
- A short course of prednisolone in chronic type B hepatitis. Report of a randomized, double-blind, placebo-controlled trial.
- The in vitro production of antibodies to mitochondrial antigens by peripheral blood mononuclear cells from patients with primary biliary cirrhosis.
- Hepatocyte growth factor stimulates invasion across reconstituted basement membranes by a new human small intestinal cell line.
- A newly identified tyrosine kinase is preferentially expressed in the gastrointestinal tract.
- Treatment of chronic type B hepatitis with multiple ten-day courses of adenine arabinoside monophosphate.
- A far upstream element stimulates c-myc expression in undifferentiated leukemia cells.
- The apical membranes of maturing gut columnar epithelial cells contain the enzymatically active form of a newly identified fyn-related tyrosine kinase.
- High-resolution chromoendoscopy for the diagnosis of diminutive colon polyps: implications for colon cancer screening.
- Specific binding of heterogeneous ribonucleoprotein particle protein K to the human c-myc promoter, in vitro.
- A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif.
- A transactivator of c-myc is coordinately regulated with the proto-oncogene during cellular growth.
- Targeted melting and binding of a DNA regulatory element by a transactivator of c-myc.
- Increased T cells lacking immunoglobulin Fc receptors and increased spontaneous morphological blast transformation in a patient with phycomycosis.
- Treatment of chronic delta hepatitis with recombinant human alpha interferon.
- Multifactorial regulation of the human c-myc oncogene.
- Delivery of c-myc antisense phosphorothioate oligodeoxynucleotides to hematopoietic cells in culture by liposome fusion: specific reduction in c-myc protein expression...
- A src-related kinase in the brush border membranes of gastrointestinal cells is regulated by c-met.
- FUSE-binding protein is developmentally regulated and is highly expressed in mouse and chicken embryonic brain.
- A new system for defining endoscopic complications emphasizing the measure of importance.
- Clinically significant liver injury in patients treated with natalizumab.
- Epidemiology of ischaemic colitis.
- Case definition and phenotype standardization in drug-induced liver injury.
- Progressive multifocal leukoencephalopathy associated with efalizumab use in psoriasis patients.
- Methylnaltrexone and gastrointestinal perforation.
- Re: Brandt et al.--An evidence-based approach to the management of irritable bowel syndrome in North America.
- An evaluation of a data mining signal for amyotrophic lateral sclerosis and statins detected in FDA''s spontaneous adverse event reporting system.
- Informatic tools and approaches in postmarketing pharmacovigilance used by FDA.
- Brief communication: characteristics of spontaneous cases of tuberculosis associated with infliximab.
- Indication and use of drug products used to treat attention-deficit/hyperactivity disorder: a cross-sectional study with inference on the likelihood of treatment in ad...
- An observational study of cholecystectomy in patients receiving tegaserod.
- U.S. Food and drug administration analysis of strokes associated with raloxifene.
- Hepatosplenic T cell lymphoma associated with infliximab use in young patients treated for inflammatory bowel disease.
- Alosetron: ischemic colitis and serious complications of constipation.
- Sodium phosphate tablets and acute phosphate nephropathy.
- Finding, evaluating, and managing drug-related risks: approaches taken by the US Food and Drug Administration (FDA).
- Hepatosplenic T cell lymphoma associated with infliximab use in young patients treated for inflammatory bowel disease: update.
- Rhabdomyolysis reports show interaction between simvastatin and CYP3A4 inhibitors.
- Telithromycin-associated hepatotoxicity: Clinical spectrum and causality assessment of 42 cases.
Schools
McGill University Faculty Of Medicine
Royal Victoria Hospital
Georgetown University Va Hosps
Harper Hospital
Doctors Specialties
- Gastroenterology
Accepted Insurances
Education
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Wayne State University School of Medicine -
McGill University Faculty of Medicine
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