Professor of Medicine Chief, Lipid Metabolism Unit
Endocrinology
Dr. Mason W. Freeman, MD
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Doctor Mason W. Freeman, MD is an expert in the field of Endocrinology. He researched medicine at University of California San Francisco School of Medicine. University of California San Francisco School of Medicine is a top medical university. University of California San Francisco School of Medicine is ranked 3 in research and 3 in primary care medicine Mason W. Freeman, MD is a published doctor as well. He has 76 publications published. The latest was: In vitro-differentiated embryonic stem cell macrophages: a model system for studying atherosclerosis-associated macrophage functions. He accepts Medicare payments and is listed with Medicare.gov.
Publications
- Exome Sequencing in Suspected Monogenic DysLipidemias.
- High-density lipoprotein-mediated cholesterol efflux capacity is improved by treatment with antiretroviral therapy in acute human immunodeficiency virus infection.
- Endogenous β-glucocerebrosidase activity in Abca12-/-epidermis elevates ceramide levels after topical Lipid application but does not restore barrier function.
- Local injection of bevacizumab (Avastin) and angiolytic KTP laser treatment of recurrent respiratory papillomatosis of the vocal folds: a prospective study.
- Wild Type and Tangier Disease ABCA1 Mutants Modulate Cellular Amyloid-? Production Independent of Cholesterol Efflux Activity.
- The Path From Bench to Bedside: Considerations Before Starting the Journey.
- Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperLipidemic mice.
- ABCA12 maintains the epidermal Lipid permeability barrier by facilitating formation of ceramide linoleic esters.
- SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter.
- Targeting Innate Immunity for CV Benefit.
- Genetic etiology of isolated low HDL syndrome: incidence and heterogeneity of efflux defects.
- ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol.
- Risk factors for coronary artery disease in patients with elevated high-density lipoprotein cholesterol.
- Scavenger receptors in atherosclerosis: beyond Lipid uptake.
- A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies.
- Statins, cholesterol, and the prevention of coronary heart disease.
- Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux.
- Loss of receptor-mediated Lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperLipidemic mice.
- Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment.
- Distinct roles of pattern recognition receptors CD14 and Toll-like receptor 4 in acute lung injury.
- Abca7 null mice retain normal macrophage phosphatidylcholine and cholesterol efflux activity despite alterations in adipose mass and serum cholesterol levels.
- Nonparametric methods for microarray data based on exchangeability and borrowed power.
- Generalized rank tests for replicated microarray data.
- Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis.
- The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades.
- ATP-binding cassette transporter A1 contains a novel C-terminal VFVNFA motif that is required for its cholesterol efflux and ApoA-I binding activities.
- Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways.
- Cross-linking and Lipid efflux properties of apoA-I mutants suggest direct association between apoA-I helices and ABCA1.
- Activation of signaling pathways by putative scavenger receptor class A (SR-A) ligands requires CD14 but not SR-A.
- CD36 mediates the innate host response to beta-amyloid.
- eLiXiRs for restraining inflammation.
- Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to Lipid loading in macrop...
- A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.
- Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice.
- Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent...
- Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I.
- C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway.
- Structure and expression of the human parathyroid hormone gene.
- Thymosin beta 4 is expressed in ROS 17/2.8 osteosarcoma cells in a regulated manner.
- The Creating an Optimal Warfarin Nomogram (CROWN) Study.
- Effluxed Lipids: Tangier Island's latest export.
- Consequences of amino-terminal deletions of preproparathyroid hormone signal sequence.
- Manipulating intestinal cholesterol absorption and hepatic cholesterol and bile acid metabolism by activation of deorphanized nuclear receptors.
- The effect of oxandrolone on low and high density lipoprotein profiles in retired breeder rats.
- Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates in...
- Of mice, men and cholesterol.
- Evidence that dendritic cells infiltrate atherosclerotic lesions in apolipoprotein E-deficient mice.
- Embryonal Stem (ES) Cell-Derived Macrophages : A Cellular System that Facilitates the Genetic Dissection of Macrophage Function.
- Mutations in signal sequence cleavage domain of preproparathyroid hormone alter protein translocation, signal sequence cleavage, and membrane-binding properties.
- Macrophage scavenger receptors.
- Episomal segregation of the adenovirus enhancer sequence by conditional genome rearrangement abrogates late viral gene expression.
- Surface expression of human CD14 in Chinese hamster ovary fibroblasts imparts macrophage-like responsiveness to bacterial endotoxin.
- Ascorbic acid oxidation product(s) protect human low density lipoprotein against atherogenic modification. Anti- rather than prooxidant activity of vitamin C in the pr...
- Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion.
- Effects of overexpression of the amino-terminal fragment of apolipoprotein B on apolipoprotein B and lipoprotein production.
- Rabbit aortic smooth muscle cells express inducible macrophage scavenger receptor messenger RNA that is absent from endothelial cells.
- Scavenger receptors in atherosclerosis.
- Peroxisome proliferator-activated receptors in macrophage biology: friend or foe?
- Stromelysin-1 (MMP-3) expression driven by a macrophage-specific promoter results in reduced viability in transgenic mice.
- Functional changes in scavenger receptor binding conformation are induced by charge mutants spanning the entire collagen domain.
- Cellular cholesterol efflux in heterozygotes for tangier disease is markedly reduced and correlates with high density lipoprotein cholesterol concentration and particl...
- Structure of the murine macrophage scavenger receptor gene and evaluation of sequences that regulate expression in the macrophage cell line, P388D.
- Novel mutations in the gene encoding ATP-binding cassette 1 in four tangier disease kindreds.
- In vitro-differentiated embryonic stem cell macrophages: a model system for studying atherosclerosis-associated macrophage functions.
- Decreased cholesterol efflux from fibroblasts of a patient without Tangier disease, but with markedly reduced high density lipoprotein cholesterol levels.
- ATP-binding cassette transporter A1 contains an NH2-terminal signal anchor sequence that translocates the protein's first hydrophilic domain to the exoplasmic space.
- The role of PPAR-gamma in macrophage differentiation and cholesterol uptake.
- Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus.
- Regulation of smooth muscle cell scavenger receptor expression in vivo by atherogenic diets and in vitro by cytokines.
- Divergent response to LPS and bacteria in CD14-deficient murine macrophages.
- Lipopolysaccharide induces scavenger receptor A expression in mouse macrophages: a divergent response relative to human THP-1 monocyte/macrophages.
- ABCA1 and amphipathic apolipoproteins form high-affinity molecular complexes required for cholesterol efflux.
- Atherosclerosis and innate immune signaling.
- Efficacy and safety of the coadministration of ezetimibe with fenofibrate in patients with mixed hyperLipidaemia.
- Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home.
Schools
University of California At San Francisco
Mass General Hospital
Massachusetts General Hospital
Harvard Med School
Mit Cambridge
Conditions Treated
- Diabetes Type 2
- Hyperkalemia
- HyperLipidemia
- Lipid Disorders
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Doctors Specialties
- Endocrinology
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- Blue Card PPO
- BlueConnect HMO
- Blue with Managed Care Behavioral Health HMO
- Preferred Blue PPO
- Cigna HMO
- Great West Healthcare-Cigna PPO
- LocalPlus
- Open Access Plus
- Commercial Insurance Company
- GHI PPO
- First Health (Coventry Health Care) PPO
- Harvard Pilgrim Health Care PPO
- Choice Care PPO
- Medicare MCR
- MultiPlan PPO
- PHCS Network PPO
- Network Health
- Tufts PPO
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
Education
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Massachusetts General Hospital -
University of California San Francisco School of Medicine
Hospital
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Massachusetts General Hospital
Drug Facts
| NPI NUMBER | 1851473821 | |
| NPPES Provider LastName | FREEMAN | |
| NPPES Provider FirstName | MASON | |
| NPPES Provider ZIPCode | 021142696 | |
| NPPES Provider State | MA | |
| Specialty Description | Endocrinology | |
| Total Claim Count | 224.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1851473821 |
| Last Name Of The Provider | FREEMAN |
| First Name Of The Provider | MASON |
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