Physician
Internal Medicine
Dr. Michal Kremen, MD
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Dr. Michal Kremen is an expert in the field of Internal Medicine. Michal Kremen has written publications. He has 8 publications published with PubMed. The lastest publication is: 'Mechanisms of urokinase plasminogen activator (uPA)-mediated atherosclerosis: role of the uPA receptor and S100A8/A9 proteins.'
Publications
- Macrophage-targeted overexpression of urokinase causes accelerated atherosclerosis, coronary artery occlusions, and premature death.
- Overexpression of urokinase by macrophages or deficiency of plasminogen activator inhibitor type 1 causes cardiac fibrosis in mice.
- Regulated transgene expression in vascular smooth muscle.
- In vivo expression of a conditional TGF-beta1 transgene: no evidence for TGF-beta1 transgene expression in SM22alpha-tTA transgenic mice.
- Plasminogen mediates the atherogenic effects of macrophage-expressed urokinase and accelerates atherosclerosis in apoE-knockout mice.
- Level of macrophage uPA expression is an important determinant of atherosclerotic lesion growth in Apoe-/- mice.
- Mechanisms of urokinase plasminogen activator (uPA)-mediated atherosclerosis: role of the uPA receptor and S100A8/A9 proteins.
Doctors Specialties
- Internal Medicine
Accepted Insurances
Education
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University of Washington
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