Physician
Family Medicine
Dr. Patricia S. Doyle, MD
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Patricia S. Doyle is an expert in the field of Family Medicine. He went to Tufts University School of Medicine. Tufts University School of Medicine has a rank of 49 in research and a 52 in primary care Patricia Doyle is a published physician. He has 34 papers published. The most current publication "Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection." Patricia Doyle accepts Medicare payments and is listed with Medicare.gov.
Publications
- Chemical-biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target.
- The Trypanosoma cruzi Protease Cruzain Mediates Immune Evasion.
- Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease.
- A nonazole CYP51 inhibitor cures Chagas' disease in a mouse model of acute infection.
- Nonpeptidic tetrafluorophenoxymethyl ketone cruzain inhibitors as promising new leads for Chagas disease chemotherapy.
- Identification and optimization of inhibitors of Trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB.
- In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi.
- Trypanosoma cruzi CYP51 inhibitor derived from a Mycobacterium tuberculosis screen hit.
- Metal compounds for the treatment of parasitic diseases.
- Identification of a new class of nonpeptidic inhibitors of cruzain.
- A cysteine protease inhibitor cures Chagas' disease in an immunodeficient-mouse model of infection.
- Bis-acridines as lead antiparasitic agents: structure-activity analysis of a discrete compound library in vitro.
- Synthesis and structure-activity relationship study of potent trypanocidal thio semicarbazone inhibitors of the trypanosomal cysteine protease cruzain.
- Leishmania: immunochemical comparison of the secretory (extracellular) acid phosphatases from various species.
- Anti-Cryptosporidium parvum antibodies inhibit infectivity in vitro and in vivo.
- Hypoxanthine, guanine, xanthine phosphoribosyltransferase activity in Cryptosporidium parvum.
- The activity of tricyclic antidepressant drugs against Trypanosoma cruzi.
- Leishmania mexicana mexicana: quantitative analysis of the intracellular cycle.
- Leishmania donovani: long-term culture of axenic amastigotes at 37 degrees C.
- Development of protease inhibitors for protozoan infections.
- Trypanosoma cruzi: quantification and analysis of the infectivity of cloned stocks.
- Trypanosoma cruzi: biological characterization of clones derived from chronic chagasic patients. II. Quantitative analysis of the intracellular cycle.
- Drugs targeting parasite lysosomes.
- Isolate-dependent differences in the oxidative metabolism of Trypanosoma cruzi epimastigotes.
- Trypanosoma cruzi: of man, kissing-bugs, and frogs.
- Potency and selectivity of P2/P3-modified inhibitors of cysteine proteases from trypanosomes.
- Two approaches to discovering and developing new drugs for Chagas disease.
- Cysteine protease inhibitors alter Golgi complex ultrastructure and function in Trypanosoma cruzi.
- Upregulation of the secretory pathway in cysteine protease inhibitor-resistant Trypanosoma cruzi.
- [Trypanocidal effect of cysteine protease inhibitors in vitro and in vivo in experimental Chagas disease].
- Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection.
- Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain.
- Synthesis and structure-activity relationships of parasiticidal thiosemicarbazone cysteine protease inhibitors against Plasmodium falciparum, Trypanosoma brucei, and T...
Schools
Tufts University
Maine Dartmouth Fp Res
Doctors Specialties
- Family Medicine
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- Pathway X Enhanced/Ind Guided Access ME
- Blue Card PPO
- Cigna HMO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- Open Access Plus
- Commercial Insurance Company
- First Health (Coventry Health Care) PPO
- Harvard Pilgrim Health Care PPO
- Humana
- Mail Handlers Benefit Plan (MHBP)
- Medicare MCR
- MultiPlan PPO
- PHCS Network PPO
- Choice Plus POS
- Navigate POS
- Options PPO
Education
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Tufts University School of Medicine
Drug Facts
| NPI NUMBER | 1801851654 | |
| NPPES Provider LastName | DOYLE | |
| NPPES Provider FirstName | PATRICIA | |
| NPPES Provider ZIPCode | 049455214 | |
| NPPES Provider State | ME | |
| Specialty Description | Family Practice | |
| Total Claim Count | 4665.0 | |
| Distinct Opioid Count | 6.0 | |
| Opioid Claim Count | 292.0 | |
| Percent Opioid Claims | 6.26 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1801851654 |
| Last Name Of The Provider | DOYLE |
| First Name Of The Provider | PATRICIA |
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