Physician
Pathology
Dr. Paul Mischel, MD
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Paul Mischel, MD practices Pathology. He went to medical school at Weill Cornell Medical College of Cornell University. Weill Cornell Medical College of Cornell University has a rank of 18 in research and a 49 in primary care He received awards:"America's Top Doctors", "Top Doctors:San Diego Area", "America's Top Doctors for Cancer", "Top Doctors:Southern California" and "Elected Member". Paul Mischel is a published doctor as well. He has 27 publications published. The latest was: mTORC2 and Metabolic Reprogramming in GBM: at the Interface of Genetics and Environment.
Publications
- Metabolic Reprogramming in Brain Cancer: A Coordinated Effort.
- mTORC2 and Metabolic Reprogramming in GBM: at the Interface of Genetics and Environment.
- A urokinase receptor-Bim signaling axis emerges during EGFR inhibitor resistance in mutant EGFR glioblastoma.
- Emerging function of mTORC2 as a core regulator in glioblastoma: metabolic reprogramming and drug resistance.
- Tumor suppressive miR-148a is silenced by CpG island hypermethylation in IDH1 mutant gliomas.
- Brain Malignancy Steering Committee clinical trials planning workshop: Report from the Targeted Therapies Working Group.
- mTORC2 in the center of cancer metabolic reprogramming.
- mTORC2 dictates Warburg effect and drug resistance.
- Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.
- mTOR Complex 2 Controls Glycolytic Metabolism in Glioblastoma through FoxO Acetylation and Upregulation of c-Myc.
- The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas.
- Fast Metabolic Response to Drug Intervention Through Analysis on a Miniaturized, Highly Integrated Molecular Imaging System.
- Glioblastoma: From Molecular Pathology to Targeted Treatment.
- Lyophilized brain tumor specimens can be used for histologic, nucleic acid, and protein analyses after 1 year of room temperature storage.
- EGFR Mutation-Induced Alternative Splicing of Max Contributes to Growth of Glycolytic Tumors in Brain Cancer.
- Probabilistic radiographic atlas of glioblastoma phenotypes.
- Hypoxia induces a phase transition within a kinase signaling network in cancer cells.
- A Tale of Two Approaches: Complementary Mechanisms of Cytotoxic and Targeted Therapy Resistance May Inform Next Generation Cancer Treatments.
- Combined analysis of O6-methylguanine-DNA methyltransferase protein expression and promoter methylation provides optimized prognostication of glioblastoma outcome.
- A Kinome-Wide RNAi Screen in Drosophila Glia Reveals That the RIO Kinases Mediate Cell Proliferation and Survival through TORC2-Akt Signaling in Glioblastoma.
- LKB1 Inactivation Dictates Therapeutic Response of Non-Small Cell Lung Cancer to the Metabolism Drug Phenformin.
- Pilot Study on "Pericytic Mimicry" and Potential Embryonic/Stem Cell Properties of Angiotropic Melanoma Cells Interacting with the Abluminal Vascular Surface.
- Phase I/II trial of erlotinib and temozolomide with radiation therapy in the treatment of newly diagnosed glioblastoma multiforme: North Central Cancer Treatment Group...
- Tumor cells with low proteasome subunit expression predict overall survival in head and neck cancer patients.
- Protective properties of radio-chemoresistant glioblastoma stem cell clones are associated with metabolic adaptation to reduced glucose dependence.
- When is hub gene selection better than standard meta-analysis?
Schools
Weill Cornell Medical College
UCLA Med Center
UCLA Med CtrUCLA D Geffen School
UCLA Neuropsych Hospital
Doctors Specialties
- Neuropathology
- Pathology
Accepted Insurances
- Blue Card PPO
- First Health (Coventry Health Care) PPO
- Heritage Signature
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
Awards
- America's Top Doctors
- Top Doctors:San Diego Area
- America's Top Doctors for Cancer
- Top Doctors:Southern California
- Elected Member
Education
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UCLA Medical Center -
UCLA Neuropsychology Hospital -
Weill Cornell Medical College of Cornell University
Hospital
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Ronald Reagan UCLA Medical Center
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