Physician

General Surgery

Peter P. Metrakos practices General Surgery. Peter Metrakos is also a published MD. He has 100 publication published. The most recent publication is: Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells: a quantitative double-label immunohistochemical analysis.

Publications

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• Proteomic analysis of ischemia-reperfusion injury upon human liver transplantation reveals the protective role of IQGAP1.
• Successful liver transplantation using the liver of donors with cystic fibrosis.
• Veno-atrial bypass for the operative treatment of septic gas gangrene secondary to delayed hepatic artery thrombosis.
• Reduced dose Thymoglobulin, tacrolimus, and mofetil mycophenolate results in excellent solitary pancreas transplantation outcomes.
• Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy.
• Aberrant right hepatic artery: a mockery.
• Anti-CD25 monoclonal antibody coverage allows for calcineurin inhibitor "holiday" in solid organ transplant patients with acute renal dysfunction.
• Aberrations in hemostasis and coagulation in untreated discordant hepatic xenotransplantation: studies in the dog-to-pig model.
• Hepatic sinusoidal endothelium upregulates IL-1alpha, IFN-gamma, and iNOS in response to discordant xenogeneic islets in an in vitro model of xenoislet transplantation.
• Elevation of CA-125 level is due to abdominal distension in liver transplantation candidates.
• Pseudoaneurysm of the superior mesenteric artery after pancreas transplantation treated by endovascular stenting.
• Successful outcome after transplantation of a donor liver with focal nodular hyperplasia.
• Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth facto...
• Decreasing viral load pretransplant and passive immunoprophylaxis with hepatitis B immunoglobulin posttransplant prevents hepatitis B virus recurrence after liver tran...
• Activation of porcine hepatic microvascular sinusoidal endothelial cells in pig-to-human liver xenotransplantation.
• Rejection of pig liver xenografts in patients with liver failure: implications for xenotransplantation.
• Donor-specific portal transfusion augments microchimerism in a porcine model of small bowel transplantation.
• Liver transplantation in a Jehovah''s Witness with ankylosing spondylitis.
• Experimental discordant hepatic xenotransplantation in the recipient with liver failure: implications for clinical bridging trials.
• Use of older donor livers is associated with more extensive ischemic damage on intraoperative biopsies during liver transplantation.
• Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells: a quantitative double-label immunohistochemical analysis.
• Comparison of neoral dose monitoring with cyclosporine through levels versus 2-hr postdose levels in stable liver transplant patients.
• Conversion from bladder to enteric drainage after pancreaticoduodenal transplantations.
• Renal pedicle torsion after simultaneous kidney-pancreas transplantation.
• Cyclosporine peak levels provide a better correlation with the area-under-the-curve than trough levels in liver transplant patients treated with neoral.
• Optimal time points for the prediction of the area-under-the-curve in liver transplant patients receiving tacrolimus.
• Pulmonary injury in recipients of discordant hepatic and renal xenografts in the dog-to-pig model.
• Recurrence-free long-term survival after liver transplantation for hepatitis B using interferon-alpha pretransplant and hepatitis B immune globulin posttransplant.
• Influence of macrophage depletion on bacterial translocation and rejection in small bowel transplantation.
• Alterations in pancreatic microcirculation and expression of endothelin-1 in a model of chronic pancreatitis.
• An analysis of late deaths after liver transplantation.
• Central pontine myelinolysis and cyclosporine neurotoxicity following liver transplantation.
• Intercellular communication and maintenance of islet cell mass--implications for islet transplantation.
• Cyclosporine and islet mass--implications for islet transplantation.
• Submucosal transplantation of pancreatic islets.
• Paracrine signaling (duct-->islet) in the pancreas and maintenance of islet cell mass--potential implications for islet transplantation.
• Collagen gel matrix promotes islet cell proliferation.
• Metabolic evaluation of islets transplanted into the submucosal space.
• Cyclosporine A blockade of the induction of ornithine decarboxylase activity as a cause of failure of islet cell proliferation and differentiation.
• Isolation and culture of intralobular ducts from the hamster pancreas.
• Deep hypothermic circulatory arrest for blunt retrohepatic venous injury: a case report.
• Trophic stimulation of adult human islets in vitro.
• Isolation of hamster islets by intraductal collagenase infusion and bovine serum albumin density gradient purification.
• Prediction of the glomerular filtration rate using equations in kidney-pancreas transplant patients receiving cimetidine.
• Novel two-step resection for lesions between the middle hepatic vein and vena cava which allows the middle hepatic vein to be preserved.
• Abnormal expression and processing of the proprotein convertases PC1 and PC2 in human colorectal liver metastases.
• Liver transplantation for incidental cholangiocarcinoma: analysis of the Canadian experience.
• Antithymocyte globulin induction therapy in hepatitis C-positive liver transplant recipients.
• Preoperative evaluation of laparoscopic living renal donors with computerized tomography and its effect on donor morbidity and graft function.
• Best single time points as surrogates to the tacrolimus and mycophenolic acid area under the curve in adult liver transplant patients beyond 12 months of transplantation.
• Leukoreduction and acute rejection in liver transplantation: an interim analysis.
• The impact of thymoglobulin on renal function and calcineurin inhibitor initiation in recipients of orthotopic liver transplant: a retrospective analysis of 298 consec...
• Endoscopic stenting as first-line treatment in duct of Lushka leaks after choledochocystic anastomosis in two cases of liver transplantation.
• Blood product use during orthotopic liver transplantation.
• Quantification of donor microchimerism in sex-mismatched porcine allotransplantation by competitive PCR.
• Optimization of cardiac preload during laparoscopic donor nephrectomy: a preliminary study of central venous pressure versus esophageal Doppler monitoring.
• Saudi guidelines for the diagnosis and management of hepatocellular carcinoma: technical review and practice guidelines.
• Renal function in recipients of pancreas transplant alone.
• Predictors of response to radio-embolization (TheraSphere®) treatment of neuroendocrine liver metastasis.
• Allocation of renal grafts to older recipients does not result in loss of functioning graft-years.
• Early changes in kidney function predict long-term chronic kidney disease and mortality in patients after liver transplantation.
• High-dose insulin therapy reduces postoperative liver dysfunction and complications in liver resection patients through reduced apoptosis and altered inflammation.
• Immunosuppression with budesonide for liver transplant recipients with severe infections.
• Multidisciplinary Canadian consensus recommendations for the management and treatment of hepatocellular carcinoma.
• Complications of ureterovesical anastomosis in adult renal transplantation: comparison of the Lich-Gregoire and the Taguchi techniques.
• Identification of the myosin heavy polypeptide 9 as a downstream effector of the proprotein convertases in the human colon carcinoma HT-29 cells.
• Type IV collagen-initiated signals provide survival and growth cues required for liver metastasis.
• Association of preoperative parameters with postoperative mortality and long-term survival after liver transplantation.
• Sunitinib malate for the treatment of pancreatic neuroendocrine tumors.
• Claudin-2 is selectively enriched in and promotes the formation of breast cancer liver metastases through engagement of integrin complexes.
• Complete response of hepatocellular carcinoma with sorafenib and Y radioembolization.
• Unresectable pancreatic adenocarcinoma: do we know who survives?
• Mechanical ventilation-induced diaphragm disuse in humans triggers autophagy.
• Re-vascularization may not increase graft survival after hepatic artery thrombosis in liver transplant recipients.
• Pathological response grade of colorectal liver metastases treated with neoadjuvant chemotherapy.
• Consensus recommendations for the diagnosis and management of well-differentiated gastroenterohepatic neuroendocrine tumours: a revised statement from a Canadian Natio...
• Successful salvage of kidney allografts threatened by ureteral stricture using pyelovesical bypass.
• Perioperative chemotherapy with bevacizumab and liver resection for colorectal cancer liver metastasis.
• Perioperative glucose and insulin administration while maintaining normoglycemia (GIN therapy) in patients undergoing major liver resection.
• Combined heart and liver transplantation on cardiopulmonary bypass: report of four cases.
• Stereotactic radiotherapy of the liver: a bridge to transplantation stereotactic radiotherapy of the liver: a bridge to transplantation.
• A "new era" in the treatment of colorectal cancer liver metastasis: the gloves are off!
• Delayed graft function has an equally bad impact on deceased donor renal graft survival in both standard criteria donors and expanded criteria donors.
• Recovery of graft function early posttransplant determines long-term graft survival in deceased donor renal transplants.
• Should trials of liver xenotransplantation proceed in toxic fulminant hepatic failure?
• Postchemotherapy characteristics of hepatic colorectal metastases: remnants of uncertain malignant potential.
• Malignant transformation of a solitary fibrous tumor of the liver and intractable hypoglycemia.
• Recurrent pyogenic cholangitis in a white woman.
• Combined simultaneous heart and liver transplantation with complete cardiopulmonary bypass support.
• Preoperative alpha-fetoprotein slope is predictive of hepatocellular carcinoma recurrence after liver transplantation.
• Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: roles in cell growth, death, and cancer.
• Hepatic protection by perioperative metabolic support?
• "First, do no harm": monitoring outcomes during the transition from open to laparoscopic live donor nephrectomy in a Canadian centre.
• Liver transplantation for metastases from a bile duct carcinoid.
• The MAP kinase phosphatase-1 MKP-1/DUSP1 is a regulator of human liver response to transplantation.
• Do biliary endoprostheses decrease biliary complications after liver transplantation?
• Ureteral implantation technique and urologic complications in adult kidney transplantion.
• Correlation of cell necrosis and tissue calcification with ischemia/reperfusion injury after liver transplantation.
• Distinct endoplasmic reticulum stress responses are triggered during human liver transplantation.

Doctors Specialties

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• Transplant Surgery
• General Surgery

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