Professor, Pediatrics, Perelman School of Medicine
Neonat/Perinatology
Dr. Phyllis A. Dennery, MD
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Phyllis Dennery is an expert in the field of Neonat/Perinatology. She graduated from Howard University College of Medicine. She has 4 awards "America's Top Doctors", "Philadelphia Magazine", "Elected Member" and "Super Doctor". Dr. Phyllis A. Dennery is also a published doctor. She has 95 paper published. The most recent paper is: Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2.
Publications
- The circadian gene Rev-erbα improves cellular bioenergetics and provides preconditioning for protection against oxidative stress.
- Even free radicals should follow some rules: A Guide to free radical research terminology and methodology.
- Nuclear Heme Oxygenase-1 (HO-1) Modulates Subcellular Distribution and Activation of Nrf2, Impacting Metabolic and Anti-oxidant Defenses.
- Sustained hyperoxia-induced NFκB activation improves survival and preserves lung development in neonatal mice.
- Heme Oxygenase In Neonatal Lung Injury and Repair.
- Signaling function of heme oxygenase proteins.
- Oxidative stress and inflammation modulate Rev-erbα signaling in the neonatal lung and affect circadian rhythmicity.
- IκBβ-Mediated NF-κB Activation Confers Protection Against Hyperoxic Lung Injury.
- Evaluating the beneficial and detrimental effects of bile pigments in early and later life.
- The NF-?B Inhibitory Protein I?B? Determines Apoptotic Cell Death Following Exposure to Oxidative Stress.
- Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations.
- Introduction to the Special Issue on Translational Research Involving Oxidative Stress.
- Silencing hyperoxia-induced C/EBP{alpha} in neonatal mice improves lung architecture via enhanced proliferation of alveolar epithelial cells.
- Oxidative stress in development: nature or nurture?
- Nitric Oxide Inhibits Hyperoxia-induced NF-kappaB Activation in Neonatal Pulmonary Microvascular Endothelial Cells.
- Zinc protoporphyrin regulates cyclin D1 expression independent of heme oxygenase inhibition.
- Manipulation of gene expression by oxygen: a primer from bedside to bench.
- Hyperoxia-induced NF-kappaB activation occurs via a maturationally sensitive atypical pathway.
- Bach1 modulates heme oxygenase-1 expression in the neonatal mouse lung.
- Society for Pediatric Research presidential address 2008: can pediatric research benefit from global warming?
- A National Agenda for America's Children and Adolescents in 2008: recommendations from the 15th Annual Public Policy Plenary Symposium, annual meeting of the Pediatric...
- trans-Arachidonic acids induce a heme oxygenase-dependent vasorelaxation of cerebral microvasculature.
- Catalytic inactive heme oxygenase-1 protein regulates its own expression in oxidative stress.
- Effects of oxidative stress on embryonic development.
- Heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress.
- Neonatal blue-light phototherapy could increase the risk of dysplastic nevus development.
- Nuclear factor-kappaB activation in neonatal mouse lung protects against lipopolysaccharide-induced inflammation.
- Heme oxygenase-2 deficiency contributes to diabetes-mediated increase in superoxide anion and renal dysfunction.
- Introduction to serial review on the role of oxidative stress in diabetes mellitus.
- Apigenin decreases hemin-mediated heme oxygenase-1 induction.
- Inhaled NO and markers of oxidant injury in infants with respiratory failure.
- Metalloporphyrins for the treatment of neonatal jaundice.
- Introduction to serial review on heme oxygenase in human disease.
- Maturational differences in lung NF-kappaB activation and their role in tolerance to hyperoxia.
- Treatment with a catalytic antioxidant corrects the neurobehavioral defect in ataxia-telangiectasia mice.
- Role of redox in fetal development and neonatal diseases.
- Interaction between heme oxygenase-1 and -2 proteins.
- Predicting neonatal brain injury: are we there yet?
- Heme oxygenase-1 induction may explain the antioxidant profile of aspirin.
- Gestational pattern of heme oxygenase expression in the rat.
- Endothelial protection by pentaerithrityl trinitrate: bilirubin and carbon monoxide as possible mediators.
- Resistance to hyperoxia with heme oxygenase-1 disruption: role of iron.
- Developmental expression of heme oxygenase in the rat lung.
- Effect of glutathione on lung activator protein-1 activation and heme oxygenase-1 induction in the immature rat.
- Heme oxygenase-1 modulates fetal growth in the rat.
- Heme oxygenase-1 induction may explain the antioxidant profile of pentaerythrityl trinitrate.
- Expression level and subcellular localization of heme oxygenase-1 modulates its cytoprotective properties in response to lung injury: a mouse model.
- Heme oxygenase-1 regulates postnatal lung repair after hyperoxia: Role of β-catenin/hnRNPK signaling.
- Pharmacological interventions for the treatment of neonatal jaundice.
- Oxygen administration in the care of neonates: a double-edged sword.
- Disrupted postnatal lung development in heme oxygenase-1 deficient mice.
- Effect of iron overload and dietary fat on indices of oxidative stress and hepatic fibrogenesis in rats.
- Preemie abandonment? Multidisciplinary experts consider how to best meet preemies needs at "preterm infants: a collaborative approach to specialized care" roundtable.
- Training and retaining of underrepresented minority physician scientists - an African-American perspective: NICHD AAP workshop on research in neonatal and perinatal me...
- HO-1 induction restores c-AMP-dependent lung epithelial fluid transport following severe hemorrhage in rats.
- Understanding newborn jaundice.
- The biology of bilirubin production.
- Melatonin: the next panacea?
- Heme oxygenase-mediated resistance to oxygen toxicity in hamster fibroblasts.
- Hyperoxic regulation of lung heme oxygenase in neonatal rats.
- Differences in basal and hyperoxia-associated HO expression in oxidant-resistant hamster fibroblasts.
- Hepatic heme oxygenase is inducible in neonatal rats during the early postnatal period.
- Ontogeny and developmental regulation of heme oxygenase.
- Duration of action and tissue distribution of zinc protoporphyrin in neonatal rats.
- Breath hydrogen excretion in infancy.
- Role of lipid peroxidation in metalloporphyrin-mediated phototoxic reactions in neonatal rats.
- Sources of carbon monoxide (CO) in biological systems and applications of CO detection technologies.
- Terminal deletion of the long arm of chromosome 2 in a premature infant with karyotype: 46,XY,del(2)(q37).
- Bilirubin measurements and long-term neurologic outcome.
- Neonatal jaundice--what now?
- Hyperbilirubinemia results in reduced oxidative injury in neonatal Gunn rats exposed to hyperoxia.
- Morphologic injury and lipid peroxidation in monolayer cultures of rabbit tracheal epithelium exposed in vitro to ozone.
- Effect of fatty acid profiles on the susceptibility of cultured rabbit tracheal epithelial cells to hyperoxic injury.
- Prostaglandin E2 attenuates hyperoxia-induced injury in cultured rabbit tracheal epithelial cells.
- Premature twins with skin lesions and gastric outlet obstruction.
- Alkalemia in a newborn infant.
- Unique effects of zinc protoporphyrin on HO-1 induction and apoptosis.
- Neonatal hyperbilirubinemia.
- Synergistic inhibition of cyclooxygenase-2 expression by vitamin E and aspirin.
- End-tidal carbon monoxide measurements in women with pregnancy-induced hypertension and preeclampsia.
- Carbon monoxide detection and biological investigations.
- A role for oxidative stress in suppressing serum immunoglobulin levels in lead-exposed Fisher 344 rats.
- Regulation and role of heme oxygenase in oxidative injury.
- HO-1 expression in type II pneumocytes after transpulmonary gene delivery.
- Heme oxygenase-1 is a cGMP-inducible endothelial protein and mediates the cytoprotective action of nitric oxide.
- Maturational differences in hyperoxic AP-1 activation in rat lung.
- Reversal of HO-1 related cytoprotection with increased expression is due to reactive iron.
- Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs.
- Simultaneous production of carbon monoxide and thiobarbituric acid reactive substances in rat tissue preparations by an iron-ascorbate system.
- Antioxidant and cytotoxic effects of bilirubin on neonatal erythrocytes.
- Protective effects of transient HO-1 overexpression on susceptibility to oxygen toxicity in lung cells.
- Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2.
- Visualizing gene expression in living mammals using a bioluminescent reporter.
- Human heme oxygenase-1 gene transfer lowers blood pressure and promotes growth in spontaneously hypertensive rats.
Schools
Howard University
Children39s National Med Center
University Hospital Of Cleveland
Doctors Specialties
- Neonatal Medicine
- Neonat/Perinatology
Accepted Insurances
Awards
- America's Top Doctors
- Philadelphia Magazine
- Elected Member
- Super Doctor
Education
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Case Western Reserve University - University Hospitals -
Children's National Medical Center - George Washington University -
Howard University College of Medicine
Hospital
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Hospital of the University of Pennsylvania -
Pennsylvania Hospital
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