Professor, Medicine, University of Florida College of Medicine
Infectious Disease
Dr. Reuben Ramphal, MD
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Dr. Reuben Ramphal works in the field of Infectious Disease. Reuben Ramphal is a published doctor and has 99 publications published. The lastest was: 'Monotherapy versus combination therapy for febrile neutropenia.' Reuben Ramphal accepts all Medicare patients.
Publications
- Basic research funding by philanthropic organizations: a case in point.
- Time to Positivity of Blood Cultures Supports Antibiotic De-escalation at 48 Hours.
- Transcriptional response of mucoid Pseudomonas aeruginosa to human respiratory mucus.
- Role of motility and flagellin glycosylation in the pathogenesis of Pseudomonas aeruginosa burn wound infections.
- Importance of adequate initial antimicrobial therapy.
- Flagellin enhances NK cell proliferation and activation directly and through dendritic cell-NK cell interactions.
- TLRs 2 and 4 are not involved in hypersusceptibility to acute Pseudomonas aeruginosa lung infections.
- Roles of specific amino acids in the N terminus of Pseudomonas aeruginosa flagellin and of flagellin glycosylation in the innate immune response.
- Extended-spectrum beta-lactamases and clinical outcomes: current data.
- Glycosylation of b-Type flagellin of Pseudomonas aeruginosa: structural and genetic basis.
- Neutrophil elastase, an innate immunity effector molecule, represses flagellin transcription in Pseudomonas aeruginosa.
- Pseudomonas aeruginosa LecB is involved in pilus biogenesis and protease IV activity but not in adhesion to respiratory mucins.
- Genetic mechanisms involved in the repression of flagellar assembly by Pseudomonas aeruginosa in human mucus.
- MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis.
- The role of flagellin versus motility in acute lung disease caused by Pseudomonas aeruginosa.
- Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation.
- Optimizing the use of carbapenems in the face of increasing Gram-negative resistance.
- Control of Pseudomonas aeruginosa in the lung requires the recognition of either lipopolysaccharide or flagellin.
- Expression of surfactant protein D in human corneal epithelial cells is upregulated by Pseudomonas aeruginosa.
- Lack of MyD88 protects the immunodeficient host against fatal lung inflammation triggered by the opportunistic bacteria Burkholderia cenocepacia.
- Pseudomonas aeruginosa LPS or flagellin are sufficient to activate TLR-dependent signaling in murine alveolar macrophages and airway epithelial cells.
- Sepsis induces early alterations in innate immunity that impact mortality to secondary infection.
- Type II secretion system of Pseudomonas aeruginosa: in vivo evidence of a significant role in death due to lung infection.
- Neutrophil Mobilization from the Bone Marrow during Polymicrobial Sepsis Is Dependent on CXCL12 Signaling.
- Toll-like receptor 5 (TLR5), IL-1? secretion, and asparagine endopeptidase are critical factors for alveolar macrophage phagocytosis and bacterial killing.
- Thrombocytopenia secondary to linezolid administration: what is the risk?
- fleQ, the gene encoding the major flagellar regulator of Pseudomonas aeruginosa, is sigma70 dependent and is downregulated by Vfr, a homolog of Escherichia coli cyclic...
- FleQ, the major flagellar gene regulator in Pseudomonas aeruginosa, binds to enhancer sites located either upstream or atypically downstream of the RpoN binding site.
- Extended-spectrum beta-lactamases.
- A four-tiered transcriptional regulatory circuit controls flagellar biogenesis in Pseudomonas aeruginosa.
- Sequence polymorphism in the glycosylation island and flagellins of Pseudomonas aeruginosa.
- Pseudomonas aeruginosa regulates flagellin expression as part of a global response to airway fluid from cystic fibrosis patients.
- Changes in the etiology of bacteremia in febrile neutropenic patients and the susceptibilities of the currently isolated pathogens.
- Interaction of the antiactivator FleN with the transcriptional activator FleQ regulates flagellar number in Pseudomonas aeruginosa.
- Identification and functional characterization of flgM, a gene encoding the anti-sigma 28 factor in Pseudomonas aeruginosa.
- Cloning and phenotypic characterization of fleS and fleR, new response regulators of Pseudomonas aeruginosa which regulate motility and adhesion to mucin.
- Cloning and characterization of Pseudomonas aeruginosa fliF, necessary for flagellar assembly and bacterial adherence to mucin.
- The Pseudomonas aeruginosa flagellar cap protein, FliD, is responsible for mucin adhesion.
- fleN, a gene that regulates flagellar number in Pseudomonas aeruginosa.
- Identification of two distinct types of flagellar cap proteins, FliD, in Pseudomonas aeruginosa.
- FlhA, a component of the flagellum assembly apparatus of Pseudomonas aeruginosa, plays a role in internalization by corneal epithelial cells.
- A genomic island in Pseudomonas aeruginosa carries the determinants of flagellin glycosylation.
- Recognition of Lewis x derivatives present on mucins by flagellar components of Pseudomonas aeruginosa.
- Adhesion of Pseudomonas aeruginosa pilin-deficient mutants to mucin.
- A transcriptional activator, FleQ, regulates mucin adhesion and flagellar gene expression in Pseudomonas aeruginosa in a cascade manner.
- Recognition of mucin components by Pseudomonas aeruginosa.
- Structural and genetic characterization of glycosylation of type a flagellin in Pseudomonas aeruginosa.
- Characterization of Pseudomonas aeruginosa fliO, a gene involved in flagellar biosynthesis and adherence.
- Recognition of mucin by the adhesin-flagellar system of Pseudomonas aeruginosa.
- Beta-lactam-resistant Enterobacter bacteremia in febrile neutropenic patients receiving monotherapy.
- Isolation and characterization of Pseudomonas aeruginosa genes inducible by respiratory mucus derived from cystic fibrosis patients.
- Genetic analysis of Pseudomonas aeruginosa adherence: distinct genetic loci control attachment to epithelial cells and mucins.
- Differences in adhesion of Pseudomonas aeruginosa to mucin glycopeptides from sputa of patients with cystic fibrosis and chronic bronchitis.
- Modulation of Pseudomonas aeruginosa adherence to the corneal surface by mucus.
- Pseudomonas aeruginosa outer membrane adhesins for human respiratory mucus glycoproteins.
- Pilus-mediated adherence of Haemophilus influenzae to human respiratory mucins.
- Respiratory-mucin inhibition of the opsonophagocytic killing of Pseudomonas aeruginosa.
- Pseudomonas aeruginosa recognizes carbohydrate chains containing type 1 (Gal beta 1-3GlcNAc) or type 2 (Gal beta 1-4GlcNAc) disaccharide units.
- Characterization of Pseudomonas aeruginosa isolates: occurrence rates, antimicrobial susceptibility patterns, and molecular typing in the global SENTRY Antimicrobial S...
- Evolution, incidence, and susceptibility of bacterial bloodstream isolates from 519 bone marrow transplant patients.
- Adhesion of Pseudomonas aeruginosa to respiratory mucins and expression of mucin-binding proteins are increased by limiting iron during growth.
- The role of bacterial adhesion in cystic fibrosis including the staphylococcal aspect.
- Tracheobronchial mucin receptor for Pseudomonas aeruginosa: predominance of amino sugars in binding sites.
- Is monotherapy for febrile neutropenia still a viable alternative?
- Adhesion of nontypeable Haemophilus influenzae from blood and sputum to human tracheobronchial mucins and lactoferrin.
- Antibiotic therapy for enterobacter meningitis: a retrospective review of 13 episodes and review of the literature.
- Vancomycin is not an essential component of the initial empiric treatment regimen for febrile neutropenic patients receiving ceftazidime: a randomized prospective study.
- Clinical experience with single agent and combination regimens in the management of infection in the febrile neutropenic patient.
- Evidence for mucins and sialic acid as receptors for Pseudomonas aeruginosa in the lower respiratory tract.
- Adherence of Pseudomonas aeruginosa to tracheal cells injured by influenza infection or by endotracheal intubation.
- Pseudomonas aeruginosa adhesins for tracheobronchial mucin.
- Role of pili in the adherence of Pseudomonas aeruginosa to injured tracheal epithelium.
- Comparison of the activity of two broad-spectrum cephalosporins tested against 2,299 strains of Pseudomonas aeruginosa isolated at 38 North American medical centers pa...
- Flagellin concentrations in expectorations from cystic fibrosis patients.
- Role of Pseudomonas aeruginosa mucoid exopolysaccharide in adherence to tracheal cells.
- Molecular basis of mucin-Pseudomonas interactions.
- Adherence of Pseudomonas aeruginosa to human tracheobronchial mucin.
- Adherence of mucoid and nonmucoid Pseudomonas aeruginosa to acid-injured tracheal epithelium.
- Arylneuraminidase activity of Pseudomonas aeruginosa does not degrade natural substrates such as human respiratory mucins.
- A position paper on the treatment of hospital acquired pneumonia (HAP): do we need guidelines?
- Altered carbohydrate composition of salivary mucins from patients with cystic fibrosis and the adhesion of Pseudomonas aeruginosa.
- Bilateral pulmonary infiltrates in association with disseminated actinomycosis.
- Adherence of Pseudomonas aeruginosa to the injured cornea: a step in the pathogenesis of corneal infections.
- Effects of subminimal inhibitory concentrations of antibiotics on the adherence of Pseudomonas aeruginosa to tracheobronchial mucin.
- Why is Pseudomonas the colonizer and why does it persist?
- Evidence for the in vivo degradation of human respiratory mucins during Pseudomonas aeruginosa infection.
- Chronic colonization of rat airways with Pseudomonas aeruginosa.
- In vitro efficacy of six cephalosporins tested against Enterobacteriaceae isolated at 38 North American medical centres participating in the SENTRY Antimicrobial Surve...
- Cost effectiveness of cephalosporin monotherapy and aminoglycoside/ureidopenicillin combination therapy. For the treatment of febrile episodes in neutropenic patients.
- Gelsolin activates DNase I in vitro and cystic fibrosis sputum.
- Outcome of influenza infection: effect of site of initial infection and heterotypic immunity.
- Pneumonia in the compromised host including cancer patients and transplant patients.
- Monotherapy versus combination therapy for febrile neutropenia.
- The role of CFTR protein susceptibility to bacterial infections in cystic fibrosis.
- Further characterization of the tracheal receptor for Pseudomonas aeruginosa.
- [Bronchial mucins and infection in cystic fibrosis].
- Randomized, double-blind, multicenter trial comparing clinafloxacin with imipenem as empirical monotherapy for febrile granulocytopenic patients.
- Early results of a comparative trial of ceftazidime versus cephalothin, carbenicillin and gentamicin in the treatment of febrile granulocytopenic patients.
Schools
McGill University Faculty of Medicine
Montreal General Hospital
Royal Victoria Hospital
University Fla Hosps Clins
Doctors Specialties
- Infectious Disease Medicine
- Infectious Disease
Accepted Insurances
Education
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University of Florida -
McGill University Faculty of Medicine
Hospital
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UF Health Shands Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1427165448 |
| Last Name Of The Provider | RAMPHAL |
| First Name Of The Provider | REUBEN |
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