Physician

Psychiatry

Robert Sack works in the field of Psychiatry. He attended Oregon Health & Science University School of Medicine. Robert Sack is a published doctor as well. He has 58 publications published. The latest was: Morning vs evening light treatment of patients with winter depression.

Publications

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• Clinical practice. Jet lag.
• Host melatonin secretion is a timing signal for the release of W. bancrofti microfilaria into the circulation.
• Relative coordination to unknown "weak zeitgebers" in free-running blind individuals.
• Zeitgeber hierarchy in humans: resetting the circadian phase positions of blind people using melatonin.
• Assessment and management of insomnia.
• Low, but not high, doses of melatonin entrained a free-running blind person with a long circadian period.
• Circadian rhythm sleep disorders: lessons from the blind.
• The pathophysiology of jet lag.
• Circadian rhythm sleep disorders: part I, basic principles, shift work and jet lag disorders. An American Academy of Sleep Medicine review.
• Circadian rhythm sleep disorders: part II, advanced sleep phase disorder, delayed sleep phase disorder, free-running disorder, and irregular sleep-wake rhythm. An Amer...
• The human phase response curve (PRC) to melatonin is about 12 hours out of phase with the PRC to light.
• Entrainment of free-running circadian rhythms by melatonin in blind people.
• The endogenous melatonin profile as a marker for circadian phase position.
• Non-24-hour sleep-wake syndrome in a sighted man: circadian rhythm studies and efficacy of melatonin treatment.
• Effects of aging on the intrinsic circadian period of totally blind humans.
• Melatonin as a chronobiotic: treatment of circadian desynchrony in night workers and the blind.
• The role of melatonin and circadian phase in age-related sleep-maintenance insomnia: assessment in a clinical trial of melatonin replacement.
• Melatonin administration to blind people: phase advances and entrainment.
• Sleep propensity free-runs with the temperature, melatonin and cortisol rhythms in a totally blind person.
• Melatonin shifts human circadian rhythms according to a phase-response curve.
• The dim light melatonin onset as a marker for circadian phase position.
• Entrainment of a free-running human with bright light?
• Pretreatment circadian period in free-running blind people may predict the phase angle of entrainment to melatonin.
• Use of melatonin for sleep and circadian rhythm disorders.
• Exogenous melatonin's phase-shifting effects on the endogenous melatonin profile in sighted humans: a brief review and critique of the literature.
• Sleep-promoting effects of melatonin: at what dose, in whom, under what conditions, and by what mechanisms?
• Melatonin rhythms in night shift workers.
• Circadian rhythm abnormalities in totally blind people: incidence and clinical significance.
• Morning vs evening light treatment for winter depression. Evidence that the therapeutic effects of light are mediated by circadian phase shifts.
• Capturing the circadian rhythms of free-running blind people with 0.5 mg melatonin.
• Winter depression and the phase-shift hypothesis for bright light's therapeutic effects: history, theory, and experimental evidence.
• Morning vs evening light treatment of patients with winter depression.
• Melatonin marks circadian phase position and resets the endogenous circadian pacemaker in humans.
• Phase shifting the human circadian clock using melatonin.
• Free-running melatonin, sleep propensity, cortisol and temperature rhythms in a totally blind person.
• Melatonin treatment of winter depression: a pilot study.
• The effects of shifting sleep two hours within a fixed photoperiod.
• The role of melatonin and light in the human circadian system.
• Treating phase typed chronobiologic sleep and mood disorders using appropriately timed bright artificial light.
• Human circadian rhythms: lessons from the blind.
• The amplitude of endogenous melatonin production is not affected by melatonin treatment in humans.
• The use of plasma melatonin levels and light in the assessment and treatment of chronobiologic sleep and mood disorders.
• Human melatonin production decreases with age.
• A comparison of sleep detection by wrist actigraphy, behavioral response, and polysomnography.
• Light therapy and psychiatry.
• Melatonin, light and chronobiological disorders.
• Is winter depression a bipolar disorder?
• Antidepressant and circadian phase-shifting effects of light.
• Immediate and delayed effects of bright light on human melatonin production: shifting "dawn" and "dusk" shifts the dim light melatonin onset (DLMO).
• Phase delay and hypersomnia.
• Evaluation of the Actillume wrist actigraphy monitor in the detection of sleeping and waking.
• Desmethylimipramine treatment increases melatonin production in humans.
• The polysomnographic effects of clonidine on sleep disorders in posttraumatic stress disorder: a pilot study with Cambodian patients.
• Effects of morning versus evening bright light exposure on REM latency.
• The phase shift hypothesis for bright light's therapeutic mechanism of action: theoretical considerations and experimental evidence.
• The phase-shift hypothesis of seasonal affective disorder.
• Batch variation and pharmacokinetics of oral sustained release melatonin-loaded sugar spheres in human subjects.

Schools

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• Or Hlth Sci Univ Sch Of Med

• Mary Hitchcock Meml Hospital

• Nih Clin Center

• Stanford Hospital Clins

Doctors Specialties

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• Psychiatry

Accepted Insurances

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Education

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• Stanford University
• Dartmouth-Hitchcock Medical Center
• Oregon Health & Science University School of Medicine

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