Physician
Radiology
Dr. Roger L. McClellan, MD
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Roger McClellan works in the field of Radiology. He went to medical school at Tulane University School of Medicine. Roger L. McClellan, MD has written publications. He has 87 publications published with PubMed. The lastest publication is: 'Pulmonary retention and clearance of inhaled biopersistent aerosol particles: data-reducing interpolation models and models of physiologically based systems--a review ...'
Publications
- Influence of Alternative Exposure Estimates in the Diesel Exhaust Miners Study: Diesel Exhaust and Lung Cancer.
- Diesel Engine Exhaust and Lung Cancer Mortality: Time-Related Factors in Exposure and Risk.
- Toxicity of lunar dust assessed in inhalation-exposed rats.
- Time-series analyses of air pollution and mortality in the United States: a subsampling approach.
- Mutagenicity of used crankcase oils from diesel and spark ignition automobiles.
- Prospects for new information relevant to radiation protection from studies of experimental animals.
- Primary liver tumors in beagle dogs exposed by inhalation to aerosols of plutonium-238 dioxide.
- Uptake of 19 hydrocarbon vapors inhaled by F344 rats.
- Lung lavage therapy to lessen the biological effects of inhaled 144Ce in dogs.
- Distribution and biological effects of inhaled 239Pu(NO3)4 in cynomolgus monkeys.
- Effects of inhaled diesel exhaust on immune responses after lung immunization.
- Chemical and biological properties of diesel exhaust particles collected during selected segments of a simulated driving cycle.
- Future development of biological understanding of radiation protection: implications of nonstochastic effects.
- Toxicity of selenium compounds to alveolar macrophages.
- A stimulation model describing the metabolism of inhaled and ingested selenium compounds.
- Distribution, retention, and fate of 2-aminoanthracene in rats after inhalation.
- Retention of monodisperse or polydisperse aluminosilicate particles inhaled by dogs, rats, and mice.
- Establishing aerosol exposure concentrations for inhalation toxicity studies.
- Preparing for the twenty-first century: report of the TOX-90's Commission. Planning Committee.
- Variability in target organ deposition among individuals exposed to toxic substances.
- A rapid method for determining soot content of lungs in diesel-exposed rodents.
- Dose-response relationships for bone cancers from plutonium in dogs and people.
- Use of mechanistic data in assessing human risks from exposure to particles.
- Deposition and retention of 0.1 micron 67Ga2O3 aggregate aerosols in rats following whole body exposures.
- Evaluation of a multitiered inhalation exposure chamber.
- Generation, characterization and inhalation deposition of ultrafine aggregate aerosols.
- Deposition and retention of inhaled aggregate 67Ga2O3 particles in beagle dogs, Fischer-344 rats, and CD-1 mice.
- Lung retention of diesel soot and associated organic compounds.
- Comparison of lung burdens of inhaled particles of rats exposed during the day or night.
- Role of inhalation studies with animals in defining human health risks for vehicle and power plant emissions.
- Carcinogenicity of diesel exhaust inhaled chronically by rats.
- A comparison of genotoxicity of automotive exhaust particles from laboratory and environmental sources.
- Influence of ethanol and methanol gasoline blends on the mutagenicity of particulate exhaust extracts.
- Mutagenicity of diesel exhaust particle extracts: influence of fuel composition in two diesel engines.
- Mutagenicity of diesel exhaust particle extracts: influence of car type.
- Response of rodents to inhaled diluted diesel exhaust: biochemical and cytological changes in bronchoalveolar lavage fluid and in lung tissue.
- Respiratory tract clearance of 14C-labeled diesel exhaust compounds associated with diesel particles or as a particle-free extract.
- 1985 Stokinger lecture. Health effects of diesel exhaust: a case study in risk assessment.
- Health effects of exposure to diesel exhaust particles.
- Health effects of diesel exhaust. A contemporary air pollution issue.
- Mutagenicity of diesel exhaust particle extracts: influence of non-petroleum fuel extenders.
- Mutagenicity of diesel exhaust particle extracts: influence of driving cycle and environmental temperature.
- Cytotoxicity of diesel exhaust particle extract--a comparison among five diesel passenger cars of different manufactures.
- Risk estimators for radiation-induced bone marrow syndrome lethality in humans.
- Potential health risks from increased use of diesel light duty vehicles.
- Effects of repeated inhalation exposures to 1-nitropyrene, benzo[a]pyrene, Ga2O3 particles, and SO2 alone and in combinations on particle clearance, bronchoalveolar la...
- Alterations in particle accumulation and clearance in lungs of rats chronically exposed to diesel exhaust.
- Generation and characterization of radiolabeled diesel exhaust.
- Inhalation of 1-nitropyrene associated with ultrafine insoluble particles or as a pure aerosol: a comparison of deposition and biological fate.
- Clearance of diesel soot particles from rat lung after a subchronic diesel exhaust exposure.
- Assessing health risks of synthetic vitreous fibers: an integrative approach.
- Pulmonary retention and clearance of inhaled biopersistent aerosol particles: data-reducing interpolation models and models of physiologically based systems--a review ...
- Reducing uncertainty in risk assessment by using specific knowledge to replace default options.
- Diesel exhaust is a pulmonary carcinogen in rats exposed chronically by inhalation.
- Metabolism of 1-[14C]nitropyrene in respiratory tract tissue of rats exposed to diesel exhaust.
- Studies on the ability of rat lung and liver microsomes to facilitate transfer and metabolism of benzo[a]pyrene from diesel particles.
- Diesel exhaust is not a pulmonary carcinogen in CD-1 mice exposed under conditions carcinogenic to F344 rats.
- Human health risk assessment: a historical overview and alternative paths forward.
- Biologically based modeling in toxicology research.
- Modeling accumulations of particles in lung during chronic inhalation exposures that lead to impaired clearance.
- Retention patterns for inhaled particles in the lung: comparisons between laboratory animals and humans for chronic exposures.
- The role of DNA adducts in diesel exhaust-induced pulmonary carcinogenesis.
- Risk assessment and biological mechanisms: lessons learned, future opportunities.
- Pharmacokinetics and cancer risk assessments.
- Inhalation toxicology of diesel exhaust particles.
- Effects of adsorption of benzo[a]pyrene onto carbon black particles on levels of DNA adducts in lungs of rats exposed by inhalation.
- Lung retention and metabolic fate of inhaled benzo(a)pyrene associated with diesel exhaust particles.
- A commentary on the NRC report "Science and judgment in risk assessment".
- Role of biopersistence in the pathogenicity of man-made fibers and methods for evaluating biopersistence: a summary of two round-table discussions.
- Species differences in release of arachidonate metabolites in response to inhaled diluted diesel exhaust.
- Distribution of DNA adducts in the respiratory tract of rats exposed to diesel exhaust.
- Evidence of health impacts of sulfate-and nitrate-containing particles in ambient air.
- Approaches to evaluating the toxicity and carcinogenicity of man-made fibers: summary of a workshop held November 11-13, 1991, Durham, North Carolina.
- Product stewardship and science: Safe manufacture and use of fiber glass.
- Particulate matter in new technology diesel exhaust (NTDE) is quantitatively and qualitatively very different from that found in traditional diesel exhaust (TDE).
- Linear low-dose extrapolation for noncancer heath effects is the exception, not the rule.
- Xu et al. "Diesel exhaust exposure induces angiogenesis" [Toxicol. Lett. 191 (2009) 57-68].
- Critical review of the human data on short-term nitrogen dioxide (NO2) exposures: evidence for NO2 no-effect levels.
- Critical considerations in evaluating scientific evidence of health effects of ambient ozone: a conference report.
- Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework.
- Development of safety qualification thresholds and their use in orally inhaled and nasal drug product evaluation.
- Carcinogenicity studies of diesel engine exhausts in laboratory animals: a review of past studies and a discussion of future research needs.
- Comment on "Fuels for urban transit buses: a cost-effectiveness analysis".
- The legacy of Leon Golberg (1915-1987).
- Setting ambient air quality standards for particulate matter.
- Mutagenicity of emissions from a natural gas fueled truck.
Schools
Tulane University of Louisiana
St Francis Hospital
Veterans Hospital
Doctors Specialties
- Diagnostic Radiology
- Radiology
Accepted Insurances
Education
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Tulane University School of Medicine
Hospital
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Duke University Hospital
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