Professor, Neurology, UCSF School of Medicine
Neurology
Dr. Samuel Pleasure, MD
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Samuel Pleasure, MD practices Neurology. He went to medical school at Perelman School of Medicine at the University of Pennsylvania. He received awards:"Glenn W. Johnson, Jr. Memorial Endowed Chair in Neurology", "CMS Meaningful Use Stage 1 Certification", "Winner of Outstanding Faculty Mentorship Award", "Nominated for Outstanding Faculty Mentorship Award", "Elected Fellow", "Elected to membership in the Cajal Club", "Appointed to Robert B. and Elinor Aird Endowed Chair of Neurology", "John Merck Fund Scholars Program in the Biology of Developmental Disabilities in Children", "Burroughs Wellcome Fund Career Award in the Biomedical Sciences", "Career Awardee", "Howard Hughes Postdoctoral Fellowship for Physicians", "Sheard Sanford Medical Student Award", "Robert M. Toll Prize (awarded for research relating to mental health)", "William Jeffers Award for Research Relating to Neurology", "NIH Medical Scientist Training Program (MSTP) Fellowship" and "Phi Beta Kappa Honor Society". Dr. Samuel Pleasure is a published physician. He has 92 papers published. The most current publication "Spontaneous intracranial hypotension resulting in stupor caused by diencephalic compression." Samuel Pleasure accepts Medicare payments and is listed with Medicare.gov.
Publications
- Migration of Oligodendrocyte Progenitor Cells Is Controlled by Transforming Growth Factor β Family Proteins during Corticogenesis.
- Heterogeneously Expressed fezf2 Patterns Gradient Notch Activity in Balancing the Quiescence, Proliferation, and Differentiation of Adult Neural Stem Cells.
- Wrong place, wrong time: ectopic progenitors cause cortical heterotopias.
- The quintessence of quiescence.
- The development of hippocampal cellular assemblies.
- Foxc1 is required by pericytes during fetal brain angiogenesis.
- The Ventral Hippocampus Is the Embryonic Origin for Adult Neural Stem Cells in the Dentate Gyrus.
- Bone morphogenic protein signaling is a major determinant of dentate development.
- CoupTFI Interacts with Retinoic Acid Signaling during Cortical Development.
- The GAP between Axon Pruning and Repulsion.
- Wnt signaling and forebrain development.
- Meningeal Defects alter the tangential migration of cortical interneurons in Foxc1hith/hith mice.
- Oligogenesis and Oligodendrocyte Progenitor Maturation Vary in Different Brain Regions and Partially Correlate with Local Angiogenesis after Ischemic Stroke.
- Wnt5a controls neurite development in olfactory bulb interneurons.
- An inducible transgenic Cre mouse line for the study of hippocampal development and adult neurogenesis.
- Exciting information for inhibitory neurons.
- Wnt signaling regulates neuronal differentiation of cortical intermediate progenitors.
- We have got you 'covered': how the meninges control brain development.
- CXCR4 and CXCR7 have distinct functions in regulating interneuron migration.
- Inducible genetic lineage tracing of cortical hem derived cajal-retzius cells reveals novel properties.
- Sox10 directs neural stem cells toward the oligodendrocyte lineage by decreasing Suppressor of Fused expression.
- Wnts influence the timing and efficiency of oligodendrocyte precursor cell generation in the telencephalon.
- Primary cellular meningeal defects cause neocortical dysplasia and dyslamination.
- There's no place like home for a neural stem cell.
- Wnt signaling in development and Disease.
- A transgenic Cre mouse line for the study of cortical and hippocampal development.
- Retinoic acid from the meninges regulates cortical neuron generation.
- Isoflurane inhibits growth but does not cause cell death in hippocampal neural precursor cells grown in culture.
- Characterization of the Frizzled10-CreER transgenic mouse: an inducible Cre line for the study of Cajal-Retzius cell development.
- Ocular coloboma and dorsoventral neuroretinal patterning defects in Lrp6 mutant eyes.
- Generation of Frizzled10-Cre transgenic mouse line: a useful tool for the study of dorsal telencephalic development.
- COUP-TFI coordinates cortical patterning, neurogenesis, and laminar fate and modulates MAPK/ERK, AKT, and beta-catenin signaling.
- NMDA receptors inhibit synapse unsilencing during brain development.
- Hypothalamic hamartomas and hedgehogs: not a laughing matter.
- Regional distribution of cortical interneurons and development of inhibitory tone are regulated by Cxcl12/Cxcr4 signaling.
- Cortical dysplasia and skull defects in mice with a Foxc1 allele reveal the role of meningeal differentiation in regulating cortical development.
- Stromal-derived factor-1 (CXCL12) regulates laminar position of Cajal-Retzius cells in normal and dysplastic brains.
- Embryonic and early postnatal abnormalities contributing to the development of hippocampal malformations in a rodent model of dysplasia.
- A tale of two signals: Wnt and Hedgehog in dentate neurogenesis.
- Aberrant seizure-induced neurogenesis in experimental temporal lobe Epilepsy.
- Laminar organization of the mouse dentate gyrus: insights from BETA2/Neuro D mutant mice.
- Severe defects in dorsal thalamic development in low-density lipoprotein receptor-related protein-6 mutants.
- Frizzled-9 promoter drives expression of transgenes in the medial wall of the cortex and its chief derivative the hippocampus.
- Wnt signaling mutants have decreased dentate granule cell production and radial glial scaffolding abnormalities.
- Stereotyped pruning of long hippocampal axon branches triggered by retraction inducers of the semaphorin family.
- ATP-binding cassette transporter ABCA2 (ABC2) expression in the developing spinal cord and PNS during myelination.
- Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain.
- Loss of Wdfy3 in mice alters Cerebral cortical neurogenesis reflecting aspects of the autism pathology.
- Neural crest-derived mesenchymal cells require wnt signaling for their development and drive invagination of the telencephalic midline.
- A Mutation in Mouse Pak1ip1 Causes Orofacial Clefting while Human PAK1IP1 Maps to 6p24 Translocation Breaking Points Associated with Orofacial Clefting.
- Ongoing interplay between the neural network and neurogenesis in the adult hippocampus.
- Identification of a transient subpial neurogenic zone in the developing dentate gyrus and its regulation by Cxcl12 and reelin signaling.
- Genetic regulation of dentate gyrus morphogenesis.
- Hilar mossy cells share developmental influences with dentate granule neurons.
- Expression of SDF-1 and CXCR4 during reorganization of the postnatal dentate gyrus.
- A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation.
- A transgenic marker mouse line labels Cajal-Retzius cells from the cortical hem and thalamocortical axons.
- Genetic control of hippocampal neurogenesis.
- Hippocampal and visuospatial learning defects in mice with a deletion of frizzled 9, a gene in the Williams syndrome deletion interval.
- Frizzled9 protein is regionally expressed in the developing medial cortical wall and the cells derived from this region.
- Morphogenesis of the dentate gyrus: what we are learning from mouse mutants.
- Expression of the BMP antagonist Dan during murine forebrain development.
- PACAP and its receptors exert pleiotropic effects in the nervous system by activating Multiple signaling pathways.
- The chemokine SDF1 regulates migration of dentate granule cells.
- Primitive neuroectodermal tumors (PNETs) of the CNS and PNS that express functional nerve growth factor receptors (NGFR) but fail to differentiate in response to NGF.
- Differentiation characteristics of newly established medulloblastoma cell lines (D384 Med, D425 Med, and D458 Med) and their transplantable xenografts.
- Human central nervous system primitive neuroectodermal tumor expressing nerve growth factor receptors: CHP707m.
- Introduction of nerve growth factor (NGF) receptors into a medulloblastoma cell line results in expression of high- and low-affinity NGF receptors but not NGF-mediated...
- Lamprey neurofilaments combine in one subunit the features of each mammalian NF triplet protein but are highly phosphorylated only in large axons.
- Glial cells of the lamprey nervous system contain keratin-like proteins.
- Inducible expression of neuronal glutamate receptor channels in the NT2 human cell line.
- NTera 2 cells: a human cell line which displays characteristics expected of a human committed neuronal progenitor cell.
- Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides.
- Spontaneous intracranial hypotension resulting in stupor caused by diencephalic compression.
- Ventricular volume and transmural pressure gradient in normal pressure hydrocephalus.
- Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and Epilepsy.
- Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections.
- Unique expression patterns of cell fate molecules delineate sequential stages of dentate gyrus development.
- Correlation of clinical and neuroimaging findings in a case of rabies encephalitis.
- Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons.
- An arrow hits the Wnt signaling pathway.
- Pax-6 regulates expression of SFRP-2 and Wnt-7b in the developing CNS.
- Wnt receptors and Wnt inhibitors are expressed in gradients in the developing telencephalon.
- Differential regulation of basic helix-loop-helix mRNAs in the dentate gyrus following status epilepticus.
- Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.
- Site-specific phosphorylation of the middle molecular weight human neurofilament protein in transfected non-neuronal cells.
- Hippocampal heterotopia with molecular and electrophysiological properties of neocortical neurons.
- Neuronal production and precursor proliferation defects in the neocortex of mice with loss of function in the canonical Wnt signaling pathway.
- Pneumococcal meningitis induces apoptosis in recently postmitotic immature neurons in the dentate gyrus of neonatal rats.
- Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons.
- Genes and signaling events that establish regional patterning of the mammalian forebrain.
Schools
University Of Pennsylvania School Of Medicine
Graduate Hospital
Uc San Francisco Med Center
Conditions Treated
- Cerebral Artery Thrombosis
- Convulsions
- Dementia
- Epilepsy
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Doctors Specialties
- Neurology
Accepted Insurances
Awards
- Glenn W. Johnson, Jr. Memorial Endowed Chair in Neurology
- CMS Meaningful Use Stage 1 Certification
- Winner of Outstanding Faculty Mentorship Award
- Nominated for Outstanding Faculty Mentorship Award
- Elected Fellow
- Elected to membership in the Cajal Club
- Appointed to Robert B. and Elinor Aird Endowed Chair of Neurology
- John Merck Fund Scholars Program in the Biology of Developmental Disabilities in Children
- Burroughs Wellcome Fund Career Award in the Biomedical Sciences
- Career Awardee
- Howard Hughes Postdoctoral Fellowship for Physicians
- Sheard Sanford Medical Student Award
- Robert M. Toll Prize (awarded for research relating to mental health)
- William Jeffers Award for Research Relating to Neurology
- NIH Medical Scientist Training Program (MSTP) Fellowship
- Phi Beta Kappa Honor Society
Education
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UCSF -
University of Pennsylvania -
Perelman School of Medicine at the University of Pennsylvania
Hospital
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UCSF Medical Center
Drug Facts
| NPI NUMBER | 1215047451 | |
| NPPES Provider LastName | PLEASURE | |
| NPPES Provider FirstName | SAMUEL | |
| NPPES Provider ZIPCode | 941432202 | |
| NPPES Provider State | CA | |
| Specialty Description | Neurology | |
| Total Claim Count | 83.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1215047451 |
| Last Name Of The Provider | PLEASURE |
| First Name Of The Provider | SAMUEL |
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