Chair, Department of Obstetrics and Gynecology
Obstetrics & Gynecology
Dr. Serdar E. Bulun, MD
|
|
Give Review
Serdar Bulun is an expert in the field of Obstetrics & Gynecology. He over the years received 3 awards: "President", "Member" and "Fellow (FACOG)". Dr. Serdar E. Bulun has written publications. He has 98 publications published with PubMed. The lastest publication is: 'Fenretinide: A Potential Treatment for Endometriosis.'
Publications
- Fenretinide: A Potential Treatment for Endometriosis.
- Estrogen receptor β regulates endometriotic cell survival through serum and glucocorticoid-regulated kinase activation.
- The aberrant expression and localization of deoxyribonucleic acid methyltransferase 3B in endometriotic stromal cells.
- Human Uterine leiomyoma stem/progenitor cells expressing CD34 and CD49b initiate tumors in vivo.
- 5-hydroxymethylcytosine promotes proliferation of human Uterine leiomyoma: a biological link to a new epigenetic modification in benign tumors.
- Ovarian steroids, stem cells and uterine leiomyoma: therapeutic implications.
- Steven L. Young, MD, PhD, FACOG.
- Genome-Wide DNA Methylation Analysis Predicts an Epigenetic Switch for GATA Factor Expression in Endometriosis.
- Ovarian Endometriosis: the nemesis of eggs.
- Introduction to the guest editor: valerie L. Baker, MD.
- Aromatase and estrogen receptor α deficiency.
- Inhibition of canonical WNT signaling attenuates human leiomyoma cell growth.
- Estrogen-dependent sushi domain containing 3 regulates cytoskeleton organization and migration in breast Cancer cells.
- Paracrine activation of WNT/β-catenin pathway in Uterine leiomyoma stem cells promotes tumor growth.
- Ligand-Activated Peroxisome Proliferator-Activated Receptor β/δ Modulates Human Endometrial Cancer Cell Survival.
- Introduction to guest editor.
- Expression Profiling of Nuclear Receptors Identifies Key Roles of NR4A Subfamily in Uterine Fibroids.
- The Use of Aromatase Inhibitors for Ovulation Induction and Superovulation.
- Progesterone action in endometrial cancer, Endometriosis, uterine fibroids, and breast cancer.
- Expression of estrogen-related gene markers in breast Cancer tissue predicts aromatase inhibitor responsiveness.
- Estrogen excess associated with novel gain-of-function mutations affecting the aromatase gene.
- Cloning and characterization of a novel endothelial promoter of the human CYP19 (aromatase P450) gene that is up-regulated in breast Cancer tissue.
- WT1 and DAX-1 inhibit aromatase P450 expression in human endometrial and endometriotic stromal cells.
- Vascular endothelial growth factor up-regulates cyclooxygenase-2 expression in human endothelial cells.
- Genetic or enzymatic disruption of aromatase inhibits the growth of ectopic Uterine tissue.
- Interleukin-1beta elevates cyclooxygenase-2 protein level and enzyme activity via increasing its mRNA stability in human endometrial stromal cells: an effect mediated ...
- Mechanisms of excessive estrogen formation in Endometriosis.
- Up-regulation of cyclooxygenase-2 expression and prostaglandin synthesis in endometrial stromal cells by malignant endometrial epithelial cells. A paracrine effect med...
- Regulation of aromatase P450 expression in endometriotic and endometrial stromal cells by CCAAT/enhancer binding proteins (C/EBPs): decreased C/EBPbeta in endometriosi...
- Estrogen production and metabolism in Endometriosis.
- A modified baboon model for Endometriosis.
- Retinoic acid (RA) regulates 17beta-hydroxysteroid dehydrogenase type 2 expression in endometrium: interaction of RA receptors with specificity protein (SP) 1/SP3 for ...
- CpG dinucleotide methylation of the CYP19 I.3/II promoter modulates cAMP-stimulated aromatase activity.
- CCAAT/enhancer binding protein beta regulates aromatase expression via multiple and novel cis-regulatory sequences in Uterine leiomyoma.
- Upstream stimulatory factor-2 regulates steroidogenic factor-1 expression in Endometriosis.
- Prostaglandin E(2) induces breast Cancer related aromatase promoters via activation of p38 and c-Jun NH(2)-terminal kinase in adipose fibroblasts.
- Progesterone receptor regulates Bcl-2 gene expression through direct binding to its promoter region in Uterine leiomyoma cells.
- Differential expression of microRNA species in human Uterine leiomyoma versus normal myometrium.
- Promoter methylation regulates estrogen receptor 2 in human endometrium and Endometriosis.
- Predictors of response to aromatase inhibitors.
- Aromatase excess in Cancers of breast, endometrium and ovary.
- Regional rearrangements in chromosome 15q21 cause formation of cryptic promoters for the CYP19 (aromatase) gene.
- Regulation of 17-beta hydroxysteroid dehydrogenase type 2 in human placental endothelial cells.
- Transcriptional activation of steroidogenic factor-1 by hypomethylation of the 5' CpG island in Endometriosis.
- Novel estrogen receptor-alpha binding sites and estradiol target genes identified by chromatin immunoprecipitation cloning in breast Cancer.
- Stromal cells of Endometriosis fail to produce paracrine factors that induce epithelial 17beta-hydroxysteroid dehydrogenase type 2 gene and its transcriptional regulat...
- Aromatase expression in Uterine leiomyomata is regulated primarily by proximal promoters I.3/II.
- BRCA1 negatively regulates the Cancer-associated aromatase promoters I.3 and II in breast adipose fibroblasts and malignant epithelial cells.
- SP1 and SP3 mediate progesterone-dependent induction of the 17beta hydroxysteroid dehydrogenase type 2 gene in human endometrium.
- Paracrine-stimulated gene expression profile favors estradiol production in breast tumors.
- Aromatase inhibitors: the next generation of therapeutics for Endometriosis?
- Steroid hormones and leiomyomas.
- Progesterone resistance in Endometriosis: link to failure to metabolize estradiol.
- A novel role of sodium butyrate in the regulation of Cancer-associated aromatase promoters I.3 and II by disrupting a transcriptional complex in breast adipose fibrobl...
- Regulation of aromatase expression in estrogen-responsive breast and Uterine disease: from bench to treatment.
- Anastrazole and oral contraceptives: a novel treatment for Endometriosis.
- Aromatase in Endometriosis and uterine leiomyomata.
- Intact progesterone receptors are essential to counteract the proliferative effect of estradiol in a genetically engineered mouse model of Endometriosis.
- Estrogen regulates expression of tumor necrosis factor receptors in breast adipose fibroblasts.
- Estrogen up-regulates cyclooxygenase-2 via estrogen receptor in human Uterine microvascular endothelial cells.
- Aromatase and Endometriosis.
- Organization of the human aromatase p450 (CYP19) gene.
- Treatment of Endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: a pilot study.
- Ovulation induction in women with infertility: a new indication for aromatase inhibitors.
- The human CYP19 (aromatase P450) gene: update on physiologic roles and genomic organization of promoters.
- WT1 and DAX-1 regulate SF-1-mediated human P450arom gene expression in gonadal cells.
- Steroid receptor and aromatase expression in baboon endometriotic lesions.
- Endometriosis: the ultimate hormonal disease.
- Progestins activate the AKT pathway in leiomyoma cells and promote survival.
- High aromatase expression in Uterine leiomyoma tissues of African-American women.
- Steroidogenic factor-1 and Endometriosis.
- Prostaglandin E2 via steroidogenic factor-1 coordinately regulates transcription of steroidogenic genes necessary for estrogen synthesis in Endometriosis.
- Estrogen receptor (ER) beta regulates ERalpha expression in stromal cells derived from ovarian Endometriosis.
- Novel promoter I.8 and promoter usage in the CYP19 (aromatase) gene.
- Aromatase expression in women's Cancers.
- Regulation of breast Cancer-associated aromatase promoters.
- Genome-Wide Progesterone Receptor Binding: Cell Type-Specific and Shared Mechanisms in T47D Breast Cancer Cells and Primary Leiomyoma Cells.
- Role of Estrogen Receptor-? in Endometriosis.
- Aromatase, breast Cancer and obesity: a complex interaction.
- Endometriosis and ovarian cancer: a review of clinical, pathologic, and molecular aspects.
- Hypermethylation of the CpG island spanning from exon II to intron III is associated with steroidogenic factor 1 expression in stromal cells of Endometriosis.
- Aromatase inhibition for refractory Endometriosis-related chronic pelvic pain.
- Estrogen receptor-? and fetoplacental endothelial prostanoid biosynthesis: a link to clinically demonstrated fetal growth restriction.
- Early growth response-2 expression in Uterine leiomyoma cells: regulation and function.
- Endometriosis expresses a molecular pattern consistent with decreased retinoid uptake, metabolism and action.
- Aromatase promoter I.f is regulated by progesterone receptor in mouse hypothalamic neuronal cell lines.
- JunD and JunB integrate prostaglandin E2 activation of breast Cancer-associated proximal aromatase promoters.
- Changes in aromatase (CYP19) gene promoter usage in non-small cell lung Cancer.
- Retinoic acid inhibits endometrial Cancer cell growth via multiple genomic mechanisms.
- Altered retinoid uptake and action contributes to cell survival in Endometriosis.
- LAT1 regulates growth of Uterine leiomyoma smooth muscle cells.
- Progesterone is essential for maintenance and growth of Uterine leiomyoma.
- Progesterone receptor action in leiomyoma and endometrial Cancer.
- Transcription factor KLF11 integrates progesterone receptor signaling and proliferation in Uterine leiomyoma cells.
- 17Beta-hydroxysteroid dehydrogenase-2 deficiency and progesterone resistance in Endometriosis.
- Estrogen receptor-beta, estrogen receptor-alpha, and progesterone resistance in Endometriosis.
- Progesterone resistance and endometrial disease. Preface.
Schools
Istanbul Universitesi Cerrahpasa Tip Fakultesi
ColumbiapampS
SUNY Buffalo School Med
University Ariz College Med
University Tex Southwestern Med Center
Conditions Treated
- Endometriosis
- Menstrual Disorders (incl. Dysmenorrhea)
- Miscarriages
- Ovarian Cysts
- View All
Doctors Specialties
- Obstetrics
- Gynecology
Accepted Insurances
Awards
- President
- Member
- Fellow (FACOG)
Education
-
University at Buffalo -
Harlem Hospital Center -
University of Arizona -
Istanbul University Faculty of Medicine
Hospital
-
Northwestern Memorial Hospital
Helpful Reviews
Similar Doctors
|
|
Dr. Sayeed N. Iqbal, MD
 This Doctor is OpenDoctor Recommended.
|
|
|
Dr. John T. Picken, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Lauren F. Streicher, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Fidel Abrego, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Rose Diakos, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Seema Venkatachalam, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Elena M. Kamel, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Sherry K. Nordstrom, MD
This Doctor is OpenDoctor Recommended.
|