Professor, Neuroscience, Johns Hopkins University School of Medicine
Psychiatry
Dr. Solomon H. Snyder, MD
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Doctor Solomon H. Snyder, MD works in the field of Psychiatry. He received 2 awards: "Elected Member" and "Whos Who in Medicine and Healthcare". Solomon H. Snyder is a published doctor and has 100 publications published. The lastest was: 'Cocaine elicits autophagic cytotoxicity via a nitric oxide-GAPDH signaling cascade.'
Publications
- Cocaine elicits autophagic cytotoxicity via a nitric oxide-GAPDH signaling cascade.
- H2S: A Novel Gasotransmitter that Signals by Sulfhydration.
- Inositol pyrophosphates promote tumor growth and metastasis by antagonizing liver kinase B1.
- Rheb Inhibits Protein Synthesis by Activating the PERK-eIF2α Signaling Cascade.
- Inositol hexakisphosphate kinase-1 mediates assembly/disassembly of the CRL4-signalosome complex to regulate DNA repair and cell death.
- Melanopsin mediates light-dependent relaxation in blood vessels.
- Neurodegeneration in Huntington's disease involves loss of cystathionine γ-lyase.
- Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2.
- Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's disease.
- Modes of physiologic H2S signaling in the brain and peripheral tissues.
- Inherent variations in CO-H2S-mediated carotid body O2 sensing mediate hypertension and pulmonary edema.
- Dexras1 mediates glucocorticoid-associated adipogenesis and diet-induced obesity.
- AMPA receptor upregulation in the nucleus accumbens shell of cocaine-sensitized rats depends upon S-nitrosylation of stargazin.
- Golgi Protein ACBD3 Mediates Neurotoxicity Associated with Huntington's Disease.
- Inositol polyphosphate multikinase is a transcriptional coactivator required for immediate early gene induction.
- Neuronal nitric oxide synthase and NADPH oxidase interact to affect cognitive, affective, and social behaviors in mice.
- D-Serine in Glia and Neurons Derives from 3-Phosphoglycerate Dehydrogenase.
- Pathogenic disruption of DISC1-serine racemase binding elicits schizophrenia-like behavior via D-serine depletion.
- Gene transcription by p53 requires inositol polyphosphate multikinase as a co-activator.
- Rhes Deletion Is Neuroprotective in the 3-Nitropropionic Acid Model of Huntington's Disease.
- Inositol hexakisphosphate kinase-1 regulates behavioral responses via GSK3 signaling pathways.
- Dexras1, a Small GTPase, Is Required for Glutamate-NMDA Neurotoxicity.
- Science interminable: Blame Ben?
- S-nitrosylation of AMPA receptor GluA1 regulates phosphorylation, single-channel conductance, and endocytosis.
- The conversion of H(2)S to sulfane sulfur: authors' response.
- Hydrogen Sulfide-Linked Sulfhydration of NF-?B Mediates Its Antiapoptotic Actions.
- AMP-activated protein kinase is physiologically regulated by inositol polyphosphate multikinase.
- Hypoxic regulation of the cerebral microcirculation is mediated by a carbon monoxide-sensitive hydrogen sulfide pathway.
- Role for mTOR Signaling and Neuronal Activity in Morphine-Induced Adaptations in Ventral Tegmental Area Dopamine Neurons.
- Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia.
- Neurotrophin-mediated degradation of histone methyltransferase by S-nitrosylation cascade regulates neuronal differentiation.
- What dopamine does in the brain.
- Hydrogen Sulfide as Endothelium-Derived Hyperpolarizing Factor Sulfhydrates Potassium Channels.
- Inositol pyrophosphates as Mammalian cell signals.
- S-Nitrosylation and S-Palmitoylation Reciprocally Regulate Synaptic Targeting of PSD-95.
- Inositol hexakisphosphate kinase 1 regulates neutrophil function in innate immunity by inhibiting phosphatidylinositol-(3,4,5)-trisphosphate signaling.
- Mind molecules.
- Nutrient amino acids signal to mTOR via inositol polyphosphate multikinase.
- Serotonin, cytokines, p11, and depression.
- Glutathione is a physiologic reservoir of neuronal glutamate.
- Inositol pyrophosphates in cell death and life.
- Casein kinase-2 mediates cell survival through phosphorylation and degradation of inositol hexakisphosphate kinase-2.
- Amino acid signaling to mTOR mediated by inositol polyphosphate multikinase.
- Inositol polyphosphate multikinase is a physiologic PI3-kinase that activates Akt/PKB.
- Inositol pyrophosphates inhibit Akt signaling, thereby regulating insulin sensitivity and weight gain.
- p53-mediated apoptosis requires inositol hexakisphosphate kinase-2.
- Rhes, a physiologic regulator of sumoylation, enhances cross-sumoylation between the basic sumoylation enzymes E1 and Ubc9.
- H2S mediates O2 sensing in the carotid body.
- Aspartate racemase, generating neuronal D-aspartate, regulates adult neurogenesis.
- Serine racemase deletion protects against cerebral ischemia and excitotoxicity.
- Death-associated protein kinase-mediated cell death modulated by interaction with DANGER.
- Molecules of madness.
- Cycling the wagons for biliverdin reductase.
- Neurotransmitters, receptors, and second messengers galore in 40 years.
- S-nitrosylation of stargazin regulates surface expression of AMPA-glutamate neurotransmitter receptors.
- GOSPEL: a neuroprotective protein that binds to GAPDH upon S-nitrosylation.
- Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity.
- Bilirubin and glutathione have complementary antioxidant and cytoprotective roles.
- Glutamatergic regulation of serine racemase via reversal of PIP2 inhibition.
- Signaling by gasotransmitters.
- H2S signals through protein S-sulfhydration.
- TRP_2, a lipid/trafficking domain that mediates diacylglycerol-induced vesicle fusion.
- H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase.
- Regulation of telomere length by fatty acid elongase 3 in yeast. Involvement of inositol phosphate metabolism and Ku70/80 function.
- TRP_2: A lipid-binding/trafficking domain that mediates diacylglycerol-induced vesicle fusion.
- Palonosetron exhibits unique molecular interactions with the 5-HT3 receptor.
- S-nitrosylation/activation of COX-2 mediates NMDA neurotoxicity.
- Regulation of AMPA receptor localization in lipid rafts.
- Modulation of D-serine levels in brains of mice lacking PICK1.
- Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis.
- HSP90 regulates cell survival via inositol hexakisphosphate kinase-2.
- Seeking god in the brain--efforts to localize higher brain functions.
- Opiate receptor revisited.
- Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event.
- Inositol pyrophosphate pyrotechnics.
- Neuronal growth and survival mediated by eIF5A, a polyamine-modified translation initiation factor.
- Julius Axelrod.
- From the Cover: Antipsychotic drug-induced weight gain mediated by histamine H1 receptor-linked activation of hypothalamic AMP-kinase.
- Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation.
- The cationic amino acid transporters CAT1 and CAT3 mediate NMDA receptor activation-dependent changes in elaboration of neuronal processes via the mammalian target of ...
- Cell signaling and neuronal death.
- Ancient origin of the new developmental superfamily DANGER.
- Flexible bilayers with spontaneous curvature lead to lamellar gels and spontaneous vesicles.
- DANGER, a novel regulatory protein of inositol 1,4,5-trisphosphate-receptor activity.
- Action of TFII-I outside the nucleus as an inhibitor of agonist-induced calcium entry.
- Neuroscience. Adam finds an exciting mate.
- NMDA receptor-nitric oxide transmission mediates neuronal iron homeostasis via the GTPase Dexras1.
- Nitric oxide-GAPDH-Siah: a novel cell death cascade.
- Discovering light effects on the brain.
- Turning off neurotransmitters.
- D-aspartate regulates melanocortin formation and function: behavioral alterations in D-aspartate oxidase-deficient mice.
- Neuroprotection by pharmacologic blockade of the GAPDH death cascade.
- Alternatively spliced neuronal nitric oxide synthase mediates penile erection.
- Mutant huntingtin: nuclear translocation and cytotoxicity mediated by GAPDH.
- Dopamine receptor excess and mouse madness.
- A nitric oxide signaling pathway controls CREB-mediated gene expression in neurons.
- Messenger molecules and cell death: therapeutic implications.
- Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2.
- Genetics. Two genes link two distinct psychoses.
Schools
Georgetown University
Doctors Specialties
- Other
- Psychiatry
Accepted Insurances
Awards
- Elected Member
- Whos Who in Medicine and Healthcare
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