Professor, Pediatrics, University of Maryland School of Medicine
Pediatric Gastroenterology
Dr. Steven J. Czinn, MD
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Steven J. Czinn, MD works in the field of Pediatric Gastroenterology. He attended Case Western Reserve University School of Medicine. He received 4 awards: "Fellow (AGAF)", "Super Doctor", "Fellow (FAAP)" and "Fellow (FACG)". Steven J. Czinn is a published doctor. He has 98 publications published. The most current publication "Qualitative and quantitative analysis of the local and systemic antibody response in mice and humans with Helicobacter immunity and infection."
Publications
- Gastric LTi cells promote lymphoid follicle formation but are limited by IRAK-M and do not alter microbial growth.
- New Diagnostic Strategies for Detection of Helicobacter pylori Infection in Pediatric Patients.
- Let's Start at the Very Beginning: Addressing the Goal of Service to the Community.
- Genetic regulation of MUC1 expression by Helicobacter pylori in gastric cancer cells.
- Vaccinating against Helicobacter pylori in the developing world.
- Genome Sequences of 65 Helicobacter pylori Strains Isolated from Asymptomatic Individuals and Patients with Gastric Cancer, Peptic Ulcer Disease, or Gastritis.
- Helicobacter pylori-Induced Disruption of Monolayer Permeability and Proinflammatory Cytokine Secretion in Polarized Human Gastric Epithelial Cells.
- Gastroesophageal reflux Disease in neonates and infants : when and how to treat.
- Helicobacter pylori and Gastric Inflammation: Role of MUC1 Mucin.
- Vaccine-Induced Immunity Against Helicobacter pylori in the Absence of IL-17A.
- Maintenance of Helicobacter pylori cultures in agar stabs.
- Muc1 cell surface mucin attenuates epithelial inflammation in response to a common mucosal pathogen.
- Partial protection against Helicobacter pylori in the absence of mast cells in mice.
- Recent advances that favor development of a vaccine for Helicobacter pylori infection.
- Helicobacter pylori vaccines: is DNA the answer?
- Regulation of murine dendritic cell immune responses by Helicobacter felis antigen.
- Pyogenic granuloma of the colon in children.
- Induction of CTLA-4-mediated anergy contributes to persistent colonization in the murine model of gastric Helicobacter pylori infection.
- Colon lamina propria dendritic cells induce a proinflammatory cytokine response in lamina propria T cells in the SCID mouse model of colitis.
- Eradication of Helicobacter pylori and resolution of gastritis in the gastric mucosa of IL-10-deficient mice.
- Vaccination as a method of preventing Helicobacter pylori-associated gastric cancer.
- Helicobacter pylori infection: detection, investigation, and management.
- Treatment of Helicobacter pylori in Pediatrics.
- Absence of catalase reduces long-term survival of Helicobacter pylori in macrophage phagosomes.
- Helicobacter pylori in children and adolescents.
- Helicobacter infection: pathogenesis.
- Vaccine-induced protection against Helicobacter pylori in mice lacking both antibodies and interleukin-4.
- Protective efficacy of anti-Helicobacter pylori immunity following systemic immunization of neonatal mice.
- Vaccine-induced reduction of Helicobacter pylori colonization in mice is interleukin-12 dependent but gamma interferon and inducible nitric oxide synthase independent.
- Clearance of Helicobacter pylori Infection and Resolution of Postimmunization Gastritis in a Kinetic Study of Prophylactically Immunized Mice.
- Helicobacter pylori inflammation and immunity.
- Characterization and functional properties of gastric tissue-resident memory T cells from children, adults, and the elderly.
- Th1-Mediated Immunity against Helicobacter pylori Can Compensate for Lack of Th17 Cells and Can Protect Mice in the Absence of Immunization.
- Dyspepsia in children.
- Susceptibility of Campylobacter pylori to the newer cephalosporin antibiotics.
- Chemotaxis as a mechanism for recruitment of mucosal plasma cell precursors.
- Demonstration of a cytotoxin from Campylobacter pylori.
- In vitro susceptibility of Helicobacter pylori to trospectomycin, pirlimycin (U-57930E), mirincamycin (U-24729A) and N-demethyl clindamycin (U-26767A).
- Selective chemotaxis of subsets of B lymphocytes from gut-associated lymphoid tissue and its implications for the recruitment of mucosal plasma cells.
- Campylobacter-like organisms in association with symptomatic gastritis in children.
- Differences in genotypes of Helicobacter pylori from different human populations.
- Rapid diagnosis of Campylobacter pyloridis-associated gastritis.
- Diagnosis of Helicobacter pylori infection by means of a polymerase chain reaction assay for gastric juice aspirates.
- Gastritis associated with infection by Helicobacter pylori in humans: geographical differences.
- Effects of topical anesthetic agents on Campylobacter pylori.
- Normalizing results of 13C-urea breath testing for CO2 production rates in children.
- Techniques for the evaluation of dyspepsia in children.
- Host, heredity and helicobacter.
- Role of the host in Helicobacter Disease.
- Susceptibility of Campylobacter pylori isolated from pediatric and adult patients to seven new quinolone antibiotics and nalidixic acid.
- Helicobacter pylori acquisition and transmission: where does it all begin?
- Campylobacter pylori: a new pathogen.
- Opsonic activity of specific human IgG against Helicobacter pylori.
- Portal vein gas associated with rotavirus infection.
- Pneumatosis intestinalis and diarrhea in a child following renal transplantation.
- Intestinal lymphangiectasia in children: a study of upper gastrointestinal endoscopic biopsies.
- Evaluation of QuickVue, a rapid enzyme immunoassay test for the detection of serum antibodies to Helicobacter pylori.
- Serum IgG antibody to the outer membrane proteins of Campylobacter pylori in children with gastroduodenal Disease.
- Campylobacter pylori--associated gastritis and peptic ulcer Disease in children.
- Serodiagnosis of Helicobacter pylori in pediatric patients.
- Enlarged gastric folds in association with Campylobacter pylori gastritis.
- Relationship between gastric inflammatory response and symptoms in patients infected with Helicobacter pylori.
- Working towards a Helicobacter pylori vaccine.
- Diagnosis of Helicobacter pylori infection in adult and pediatric patients by using Pyloriset, a rapid latex agglutination test.
- Endoscopy personnel and the transmission of Helicobacter pylori infection.
- Helicobacter pylori in infants and children.
- Immunopathology of Helicobacter pylori infection and Disease.
- Famotidine for infant gastro-oesophageal reflux: a multi-centre, randomized, placebo-controlled, withdrawal trial.
- What is the role for vaccination in Helicobacter pylori?
- Diagnosis of gastritis caused by Helicobacter pylori in children by means of an ELISA.
- Protective anti-Helicobacter immunity is induced with aluminum hydroxide or complete Freund's adjuvant by systemic immunization.
- Canadian Helicobacter Study Group Consensus Conference: Update on the approach to Helicobacter pylori infection in children and adolescents--an evidence-based evaluation.
- Is repeated exposure to H. pylori necessary for chronic H. pylori infection?
- Antimicrobial resistance incidence and risk factors among Helicobacter pylori-infected persons, United States.
- Surface properties of Helicobacter mustelae and ferret gastrointestinal mucosa.
- Comparison of Helicobacter mustelae and Helicobacter pylori adhesion to eukaryotic cells in vitro.
- Recombinant cholera toxin B subunit is not an effective mucosal adjuvant for oral immunization of mice against Helicobacter felis.
- Helicobacter pylori infection in children: update.
- Vaccine strategies for prevention of Helicobacter pylori infection.
- Protection of germ-free mice from infection by Helicobacter felis after active oral or passive IgA immunization.
- Oral immunization induces humoral and cell-mediated immunity and protects germ-free mice against infection from Helicobacter felis.
- Food protein sensitivity with partial villous atrophy after pediatric liver transplantation with tacrolimus immunosuppression.
- Immunology of Helicobacter pylori and prospects for vaccine.
- Therapeutic immunization against Helicobacter mustelae in naturally infected ferrets.
- gamma-Glutamyltransferase is a Helicobacter pylori virulence factor but is not essential for colonization.
- Local and systemic antibody responses in humans with Helicobacter pylori infection.
- Host response and vaccine development to Helicobacter pylori infection.
- Qualitative and quantitative analysis of the local and systemic antibody response in mice and humans with Helicobacter immunity and infection.
- Antibody-independent protective mucosal immunity to gastric helicobacter infection in mice.
- Review article: Immunological determinants that may affect the Helicobacter pylori cancer risk.
- Murine CD4 T-cell response to Helicobacter infection: TH1 cells enhance gastritis and TH2 cells reduce bacterial load.
- Characterization and therapy for experimental infection by Helicobacter mustelae in ferrets.
- Helicobacter-specific cell-mediated immune responses display a predominant Th1 phenotype and promote a delayed-type hypersensitivity response in the stomachs of mice.
- Role of the host in pathogenesis of Helicobacter-associated gastritis: H. felis infection of inbred and congenic mouse strains.
- Urease-specific monoclonal antibodies prevent Helicobacter felis infection in mice.
- Helicobacter-associated gastritis in SCID mice.
- Oral immunization against Helicobacter pylori.
Schools
Case Western Reserve University School of Medicine
Case Western Reserve University
Conditions Treated
- Crohn's Disease (Regional Enteritis)
Doctors Specialties
- Pediatric Gastroenterology
Accepted Insurances
Awards
- Fellow (AGAF)
- Super Doctor
- Fellow (FAAP)
- Fellow (FACG)
Education
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Case Western Reserve University - University Hospitals -
Case Western Reserve University School of Medicine
Hospital
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University of Maryland Medical Center
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