Professor, Pathology, University of Tennessee Health Science Center College of Medicine
Pathology
Dr. Terrence L. Geiger, MD
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Terrence L. Geiger, MD works in the field of Pathology. He attended Yale University School of Medicine. Yale University School of Medicine is one of the top medical schools in the US. Yale University School of Medicine is ranked 7 in research and 57 in primary care medicine He has 1 awards "Elected Member". Terrence Geiger is a published MD as well. He has 71 publications published. The latest was: Antitumor activity of a C-raf antisense oligonucleotide in combination with standard chemotherapeutic agents against various human tumors transplanted subcutaneously i...
Publications
- Differential T Cell Cytokine Receptivity and Not Signal Quality Distinguishes IL-6 and IL-10 Signaling during Th17 Differentiation.
- Anti-CD33 chimeric antigen receptor targeting of acute myeloid leukemia.
- Bispecificity for myelin and neuronal self-antigens is a common feature of CD4 T cells in C57BL/6 mice.
- IL-10 modulates DSS-induced colitis through a macrophage-ROS-NO axis.
- Diversification and senescence of Foxp3(+) regulatory T cells during experimental autoimmune encephalomyelitis.
- Context and location dependence of adaptive Foxp3(+) regulatory T cell formation during immunopathological conditions.
- Nature and nurture in Foxp3(+) regulatory T cell development, stability, and function.
- A mouse model of clonal CD8+ T lymphocyte-mediated alopecia areata progressing to alopecia universalis.
- Altered Differentiation, Diminished Pathogenicity, and Regulatory Activity of Myelin-Specific T Cells Expressing an Enhanced Affinity TCR.
- Identification of errors introduced during high throughput sequencing of the T cell receptor repertoire.
- Rational design of T cell receptors with enhanced sensitivity for antigen.
- Rebalancing immune specificity and function in cancer by T-cell receptor gene therapy.
- Discrete TCR repertoires and CDR3 features distinguish effector and Foxp3+ regulatory T lymphocytes in myelin oligodendrocyte glycoprotein-induced experimental allergi...
- Induction of B-cell immune tolerance by antigen-modified cytotoxic T lymphocytes.
- T cell receptor CDR3 sequence but not recognition characteristics distinguish autoreactive effector and Foxp3(+) regulatory T cells.
- Subtle affinity-enhancing mutations in a myelin oligodendrocyte glycoprotein-specific TCR alter specificity and generate new self-reactivity.
- In vivo suppression of naive CD4 T cell responses by IL-2- and antigen-stimulated T lymphocytes in the absence of APC competition.
- Transfusion-associated immune modulation: a reason to TRIM platelet transfusions?
- Clinical and biologic features and treatment outcome of children with newly diagnosed acute myeloid leukemia and hyperleukocytosis.
- Retrogenic modeling of experimental allergic encephalomyelitis associates T cell frequency but not TCR functional affinity with pathogenicity.
- Redirecting therapeutic T cells against myelin-specific T lymphocytes using a humanized myelin basic protein-HLA-DR2-zeta chimeric receptor.
- Mitigation of experimental allergic encephalomyelitis by TGF-beta induced Foxp3+ regulatory T lymphocytes through the induction of anergy and infectious tolerance.
- Induction of tolerance and immunity by redirected B cell-specific cytolytic T lymphocytes.
- A large-scale method for the selective depletion of alphabeta T lymphocytes from PBSC for allogeneic transplantation.
- A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-beta.
- Converting antigen-specific diabetogenic CD4 and CD8 T cells to TGF-beta producing non-pathogenic regulatory cells following FoxP3 transduction.
- A revised classification scheme for acute transfusion reactions.
- Acetaminophen and diphenhydramine premedication for allergic and febrile nonhemolytic transfusion reactions: good prophylaxis or bad practice?
- Epm2a suppresses tumor growth in an immunocompromised host by inhibiting Wnt signaling.
- Defective cell cycle induction by IL-2 in naive T-cells antigen stimulated in the presence of refractory T-lymphocytes.
- Premedication with acetaminophen or diphenhydramine for transfusion with leucoreduced blood products in children.
- IL-10-dependent infectious tolerance after the treatment of experimental allergic encephalomyelitis with redirected CD4+CD25+ T lymphocytes.
- Early complications in children with acute lymphoblastic leukemia presenting with hyperleukocytosis.
- IL-10-dependent suppression of experimental allergic encephalomyelitis by Th2-differentiated, anti-TCR redirected T lymphocytes.
- Immunotherapy of autoimmune encephalomyelitis with redirected CD4+CD25+ T lymphocytes.
- A case of hemoglobin SC disease with cold agglutinin-induced hemolysis.
- Uncoupling of IL-2 signaling from cell cycle progression in naive CD4+ T cells by regulatory CD4+CD25+ T lymphocytes.
- Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia.
- A one-step large-scale method for T- and B-cell depletion of mobilized PBSC for allogeneic transplantation.
- Antigen nonspecific suppression of T cell responses by activated stimulation-refractory CD4+ T cells.
- Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2.
- Identification of a murine CD28 dileucine motif that suppresses single-chain chimeric T-cell receptor expression and function.
- Purification of human natural killer cells using a clinical-scale immunomagnetic method.
- Etiology and outcome of graft failure in pediatric hematopoietic stem cell transplant recipients.
- Functional segregation of the TCR and antigen-MHC complexes on the surface of CTL.
- Antigen-specific targeting of CD8+ T cells with receptor-modified T lymphocytes.
- Large-scale isolation of CD133+ progenitor cells from G-CSF mobilized peripheral blood stem cells.
- Targeting autoantigen-specific T cells and suppression of autoimmune encephalomyelitis with receptor-modified T lymphocytes.
- Clonal deletion of simian virus 40 large T antigen-specific T cells in the transgenic adenocarcinoma of mouse prostate mice: an important role for clonal deletion in s...
- A large-scale method for T cell depletion: towards graft engineering of mobilized peripheral blood stem cells.
- Human leucocyte antigen alloimmunization after bone marrow transplantation: an association with chronic myelogenous leukaemia.
- Absence of D alloimmunization in D- pediatric oncology patients receiving D-incompatible single-donor platelets.
- Integrated src kinase and costimulatory activity enhances signal transduction through single-chain chimeric receptors in T lymphocytes.
- Development and application of receptor-modified T lymphocytes for adoptive immunotherapy.
- Consequences of the inhibition of Hdm2 expression in human osteosarcoma cells using antisense oligonucleotides.
- Regulation of DNA synthesis in Leydig cells obtained from neonatal pig testes.
- The TCR zeta-chain immunoreceptor tyrosine-based activation motifs are sufficient for the activation and differentiation of primary T lymphocytes.
- Removal of anaphylatoxins C3a and C5a and chemokines interleukin 8 and RANTES by polyester white cell-reduction and plasma filters.
- Antitumor activity of a C-raf antisense oligonucleotide in combination with standard chemotherapeutic agents against various human tumors transplanted subcutaneously i...
- Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo.
- Inhibition of growth of human tumor cell lines in nude mice by an antisense of oligonucleotide inhibitor of protein kinase C-alpha expression.
- Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase.
- Breaking immunologic ignorance to an antigenic peptide of simian virus 40 large T antigen.
- The effect of solvent/detergent-treated plasma on red cells stored in vitro.
- Mechanisms of immune tolerance induction through the thymic expression of a peripheral tissue-specific protein.
- CGP 47969A: effect on collagen induced arthritis in DBA/1 mice.
- T cells are responsive to the simian virus 40 large tumor antigen transgenically expressed in pancreatic islets.
- Interferon alpha increases the frequency of interferon gamma-producing human CD4+ T cells.
- Neutralization of interleukin-1 beta activity in vivo with a monoclonal antibody alleviates collagen-induced arthritis in DBA/1 mice and prevents the associated acute-...
- T-cell responsiveness to an oncogenic peripheral protein and spontaneous autoimmunity in transgenic mice.
Schools
Yale University
Yale New Haven Hospital
Doctors Specialties
- Clinical Pathology
- Pathology
Accepted Insurances
Awards
- Elected Member
Education
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Yale-New Haven Hospital -
Yale University School of Medicine
Hospital
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University of Tennessee Medical Center
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