Professor, Pediatrics, Medical College of Wisconsin
Pediatric Hematology & Oncology
Dr. Thomas C. Abshire, MD
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Doctor Thomas C. Abshire, MD is an expert in the field of Pediatric Hematology & Oncology. He graduated from Tulane University School of Medicine. He received 2 awards: "Regional Top Doctor" and "Fellow (FAAP)". Thomas Abshire is a published doctor and has 77 publications published. The lastest was: 'Idarubicin and cytosine arabinoside reinduction therapy for children with multiple recurrent or refractory acute lymphoblastic leukemia: a Pediatric Oncology Group study.'
Publications
- Clinical and laboratory variability in a cohort of patients diagnosed with type 1 VWD in the United States.
- Changes in bleeding patterns in von Willebrand Disease after institution of long-term replacement therapy: results from the von Willebrand Disease Prophylaxis Network.
- Treatment of Relapsed Precursor-B Acute Lymphoblastic Leukemia With Intensive Chemotherapy: POG (Pediatric Oncology Group) Study 9411 (SIMAL 9).
- No increase in bleeding identified in type 1 VWD subjects with D1472H sequence variation.
- Prophylaxis in severe forms of von Willebrand's Disease: results from the von Willebrand Disease Prophylaxis Network (VWD PN).
- Von Willebrand factor mutations and new sequence variations identified in healthy controls are more frequent in the African-American population.
- Common VWF exon 28 polymorphisms in African Americans affecting the VWF activity assay by ristocetin cofactor.
- The "parallel-cohort RCT": Novel design aspects and application in the Kids-DOTT trial of pediatric venous thromboembolism.
- Inhibitors of factor VIII in black patients with Hemophilia.
- Diagnosis of type 1 VWD: can the clinical history trump laboratory findings?
- Recombinant tissue plasminogen activator may reduce frequency of central venous access device infection in Hemophilia patients undergoing immune tolerance therapy.
- Prophylaxis versus episodic treatment to prevent joint disease in boys with severe Hemophilia.
- Prospective phase 1/2 study of rituximab in childhood and adolescent chronic Immune thrombocytopenic purpura.
- Prophylaxis and von Willebrand's Disease (vWD).
- The safety and efficacy of recombinant human blood Coagulation factor IX in previously untreated patients with severe or moderately severe hemophilia B.
- Recent advances in the management of the child who has Hemophilia.
- Arthroscopic synovectomy for hemophilic joint Disease in a pediatric population.
- Dose optimization of recombinant factor VIIa for control of mild to moderate bleeds in inhibitor patients: Improved efficacy with higher dosing.
- Hepatitis C in adults and adolescents with Hemophilia: a randomized, controlled trial of interferon alfa-2b and ribavirin.
- Consensus on a core curriculum in American training programs in pediatric hematology-oncology: a report from the ASPHO Training Committee.
- Unraveling hemophilic arthropathy.
- The use of Hepzyme in removing heparin from blood samples drawn from central venous access devices.
- Childhood ITP: can we venture below 20 000?
- Diagnosis and management of inherited von Willebrand Disease in the next decade: panel discussion.
- ISTH/SSC bleeding assessment tool: a standardized questionnaire and a proposal for a new bleeding score for inherited bleeding Disorders.
- The von Willebrand Disease prophylaxis network: exploring a treatment concept.
- An approach to target joint bleeding in Hemophilia: prophylaxis for all or individualized treatment?
- Novel missense mutation in the Coagulation factor IX catalytic domain associated with moderate disease.
- The von Willebrand Disease prophylaxis network (vWD PN): exploring a treatment concept.
- Safety update on recombinant factor VIIa in the treatment of congenital and acquired Hemophilia.
- Efficacy of a sucrose-formulated recombinant factor VIII used for 22 surgical procedures in patients with severe haemophilia A.
- Sites of initial bleeding episodes, mode of delivery and age of diagnosis in babies with haemophilia diagnosed before the age of 2 years: a report from The Centers for...
- Comparison of venography and ultrasound for the diagnosis of asymptomatic deep vein thrombosis in the upper body in children: results of the PARKAA study. Prophylactic...
- The role of prophylaxis in the management of von Willebrand Disease: today and tomorrow.
- Comparison of the anticoagulant effect of a direct thrombin inhibitor and a low molecular weight heparin in an acquired antithrombin deficiency in children with acute ...
- Fresh frozen plasma prepared with amotosalen HCl (S-59) photochemical pathogen inactivation: transfusion of patients with congenital Coagulation factor deficiencies.
- Clinical manifestations of the prothrombin G20210A mutation in children: a pediatric Coagulation consortium study.
- The new albumin-free recombinant factor VIII concentrates for treatment of Hemophilia: do they represent an actual incremental improvement?
- Recombinant factor VIIa: review of efficacy, dosing regimens and safety in patients with congenital and acquired factor VIII or IX inhibitors.
- A prospective cohort study determining the prevalence of thrombotic events in children with acute lymphoblastic leukemia and a central venous line who are treated with...
- Safety update on the use of recombinant factor VIIa and the treatment of congenital and acquired deficiency of factor VIII or IX with inhibitors.
- Trend to efficacy and safety using antithrombin concentrate in prevention of thrombosis in children receiving l-asparaginase for acute lymphoblastic leukemia. Results ...
- Outcomes after HLA-matched sibling transplantation or chemotherapy in children with B-precursor acute lymphoblastic leukemia in a second remission: a collaborative stu...
- Clinical evaluation of moroctocog alfa (AF-CC), a new generation of B-domain deleted recombinant factor VIII (BDDrFVIII) for treatment of haemophilia A: demonstration ...
- Inhibitor development, Immune tolerance and prophylaxis in haemophilia A--the need for an evidence-based approach.
- Evaluation of factor VIII pharmacokinetics and anti-factor VIII antibodies in four boys with haemophilia A and a poor clinical response to factor VIII.
- In non-severe Hemophilia A the risk of inhibitor after intensive factor treatment is greater in older patients: a case-control study.
- Incidence of inhibitors in a cohort of 838 males with Hemophilia A previously treated with factor VIII concentrates.
- Abnormalities of prothrombin: a review of the pathophysiology, diagnosis, and treatment.
- Leukemia and P32 radionuclide synovectomy for hemophilic arthropathy.
- The Anemia of inflammation. A common cause of childhood Anemia.
- Philadelphia chromosome-positive chronic myeloid leukemia and thoracic ganglioneuroma. Previously undescribed association.
- Dysfunctional protein C deficiency (type II). A report of 11 cases in 3 American families and review of the literature.
- Prevalence of von Willebrand Disease in children: a multiethnic study.
- The prolonged thrombin time of nephrotic syndrome.
- Anemia of acute inflammation in children.
- Zinc status in children and young adults with Sickle cell disease.
- The coagulopathy of childhood leukemia. Thrombin activation or primary fibrinolysis?
- Severe neonatal protein C deficiency: prevalence and thrombotic risk.
- Relative value of diagnostic studies for von Willebrand Disease.
- Morphologic, immunologic and cytogenetic studies in children with acute lymphoblastic leukemia at diagnosis and relapse: a Pediatric Oncology Group study.
- Molecular genetic studies in black families with sickle cell Anemia and unusually high levels of fetal hemoglobin.
- Sucrose formulated recombinant human antihemophilic factor VIII is safe and efficacious for treatment of Hemophilia A in home therapy--International Kogenate-FS Study ...
- Incidence and prognostic significance of MDM2 oncoprotein overexpression in relapsed childhood acute lymphoblastic leukemia.
- Adverse events during use of intranasal desmopressin acetate for haemophilia A and von Willebrand Disease: a case report and review of 40 patients.
- Determination of heparin-induced thrombocytopenia: a rapid flow cytometric assay for direct demonstration of antibody-mediated platelet activation.
- Idarubicin and cytosine arabinoside reinduction therapy for children with multiple recurrent or refractory acute lymphoblastic leukemia: a Pediatric Oncology Group study.
- Coagulopathy in pediatric abusive head trauma.
- Weekly polyethylene glycol conjugated L-asparaginase compared with biweekly dosing produces superior induction remission rates in childhood relapsed acute lymphoblasti...
- Radionuclide synovectomy for hemophilic arthropathy: a comprehensive review of safety and efficacy and recommendation for a standardized treatment protocol.
- An approach to the diagnosis and treatment of bleeding Disorders in infants.
- IGIV-C, a novel intravenous immunoglobulin: evaluation of safety, efficacy, mechanisms of action, and impact on quality of life.
- Clinical uses of plasma and plasma fractions: plasma-derived products for Hemophilias A and B, and for von Willebrand disease.
- One year follow-up of children and adolescents with chronic Immune thrombocytopenic purpura (ITP) treated with rituximab.
- Current issues in prophylactic therapy for persons with Hemophilia.
- A community-based partnership to promote information infrastructure for bleeding Disorders.
Schools
Tulane University
David Grant Usaf Med Center
David Grant Medical Center
University Of Colorado School Of Medicine
Conditions Treated
- Anemia
- Coagulation Disorders (incl. Hemophilia)
- Hypercoagulable State
- Immune Thrombocytopenic Purpura (ITP)
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Doctors Specialties
- Pediatric Hematology
- Oncology
Accepted Insurances
Awards
- Regional Top Doctor
- Fellow (FAAP)
Education
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University of Colorado -
David Grant Medical Center -
Tulane University School of Medicine
Hospital
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Children's Hospital of Wisconsin
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