Professor, Pathology, University of Washington School of Medicine
Pathology
Dr. Thomas H. Norwood, MD
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Thomas Norwood practices Pathology. He went to medical school at University of Maryland School of Medicine. University of Maryland School of Medicine is ranked 37/52 in Research/PrimaryCare. Dr. Thomas H. Norwood is a published doctor. He has 61 publications published. The most current publication "The t(8;21) translocation is not consistently associated with high Bcl-2 expression in de novo acute myeloid leukemias of adults." He is registered with Medicare and accepts Medicare payments.
Publications
- A phase II trial of azacitidine and gemtuzumab ozogamicin therapy in older patients with acute myeloid leukemia.
- The accumulation of versican in the nodules of benign prostatic hyperplasia.
- Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis.
- Four-color flow cytometry shows strong concordance with bone marrow morphology and cytogenetics in the evaluation for myelodysplasia.
- So-called "inflammatory leiomyosarcoma'': a series of 3 cases providing additional insights into a rare entity.
- Deep-seated, well differentiated lipomatous tumors of the chest wall and extremities: the role of cytogenetics in classification and prognostication.
- Immortalization in a normal foreskin fibroblast culture following transduction of cyclin A2 or cdk1 genes in retroviral vectors.
- An unusual case of multiple giant myelolipomas: clinical and pathogenetic implications.
- Outcome after induction chemotherapy for older patients with acute myeloid leukemia is not improved with mitoxantrone and etoposide compared to cytarabine and daunorub...
- Molecular targeting of platelet-derived growth factor B by imatinib mesylate in a patient with metastatic dermatofibrosarcoma protuberans.
- Trisomy 10p: report of an unusual mechanism of formation and critical evaluation of the clinical phenotype.
- Chromosome 7 short arm deletion and craniosynostosis. A 7p-syndrome.
- Mosaicism in amniotic fluid cell cultures: classification and significance.
- Dominance of the senescent phenotype in heterokaryons between replicative and post-replicative human fibroblast-like cells.
- A simple method of rapid freezing adequately preserves brain tissue for immunocytochemistry, light and electron microscopic examination.
- A long-lived human diploid fibroblast line for cellular aging studies: applications in cell hybridization.
- Growth inhibition and morphologic modulation of human fibroblastlike cells by erythromycin.
- Cellular aging in Werner''s syndrome: a unique phenotype?
- Do hyperplastoid cell lines "differentiate themselves to death"?
- Clonal selection, attenuation and differentiation in an in vitro model of hyperplasia.
- Inhibition of DNA synthesis in young cycling human diploid fibroblast-like cells upon fusion to enucleate cytoplasts from senescent cells.
- DNA synthesis of sublethally injured cells in heterokaryons and its relevance to clonal senescence.
- Cell enlargement: one possible mechanism underlying cellular senescence.
- Chimeric del20q in a case of chronic neutrophilic leukemia.
- Variegated translocation mosaicism in human skin fibroblast cultures.
- Evidence for differences in the mechanism of cell cycle arrest between senescent and serum-deprived human fibroblasts: heterokaryon and metabolic inhibitor studies.
- Rapid kinetics of polyethylene glycol-mediated fusion.
- Complementation in heterokaryons derived from a thymidine kinase deficient cell line and senescent human diploid cells.
- Induction of DNA polymerase alpha in senescent cultures of normal and Werner's syndrome cultured skin fibroblasts.
- Antenatal diagnosis of mosaic trisomy 8 confirmed in fetal tissues.
- Chromosomal changes in a dedifferentiated chondrosarcoma: a case report and review of the literature.
- Evidence that a critical threshold of DNA polymerase-alpha activity may be required for the initiation of DNA synthesis in mammalian cell heterokaryons.
- The relationship between cell size, the activity of DNA polymerase alpha and proliferative activity in human diploid fibroblast-like cell cultures.
- Abnormal skin fibroblast cytogenetics in four dysmorphic patients with normal lymphocyte chromosomes.
- Myogenic stem cell commitment probability remains constant as a function of organismal and mitotic age.
- The cultured diploid fibroblast as a model for the study of cellular aging.
- Comparative heterokaryon study of cellular senescence and the serum-deprived state.
- A neuroendocrine/small cell prostate carcinoma xenograft-LuCaP 49.
- Familial cryptic (20;21) translocation identified by in situ hybridization technologies.
- The role of DNA damage in cellular aging: is it time for a reassessment?
- Progression to cancer in Barrett's esophagus is associated with genomic instability.
- Unexpected structural complexity of supernumerary marker chromosomes characterized by microarray comparative genomic hybridization.
- Balanced reciprocal translocation mosaicism: how frequent?
- A somatic genetic approach to the analysis of senescence in human diploid fibroblasts in vitro: from heterokaryons to molecules.
- A novel human gene encoding HECT domain and RCC1-like repeats interacts with cyclins and is potentially regulated by the tumor suppressor proteins.
- A mouse model for cyclin E-dependent genetic instability and tumorigenesis.
- The t(8;21) translocation is not consistently associated with high Bcl-2 expression in de novo acute myeloid leukemias of adults.
- Cell cycle perturbations in acute myeloid leukemia samples following in vitro exposures to therapeutic agents.
- Analysis of the capacity of extracts from normal human young and senescent fibroblasts to support DNA synthesis in vitro.
- Satellite 2 methylation patterns in normal and ICF syndrome cells and association of hypomethylation with advanced replication.
- A phase II study of high dose ARA-C and mitoxantrone for treatment of relapsed or refractory adult acute lymphoblastic leukemia.
- The relationship between the rate of entry into S phase, concentration of DNA polymerase alpha, and cell volume in human diploid fibroblast-like monokaryon cells.
- Role of cyclin E and cyclin E-dependent kinase in mitogenic stimulation by cementum-derived growth factor in human fibroblasts.
- Measurement of spontaneous and therapeutic agent-induced apoptosis with BCL-2 protein expression in acute myeloid leukemia.
- Murine temperature-sensitive DNA polymerase alpha mutant displays a diminished capacity to stimulate DNA synthesis in senescent human fibroblast nuclei in heterokaryon...
- Persistent clonal areas and clonal expansion in Barrett's esophagus.
- A distinctive nuclear morphology in acute myeloid leukemia is strongly associated with loss of HLA-DR expression and FLT3 internal tandem duplication.
- DNA polymerase alpha and the regulation of entry into S phase in heterokaryons.
- Extended lifespan of Barrett''s esophagus epithelium transduced with the human telomerase catalytic subunit: a useful in vitro model.
- Abnormal X: autosome ratio, but normal X chromosome inactivation in human triploid cultures.
Schools
University Of Maryland School Of Medicine
University Wash Hospital Seattle
Doctors Specialties
- Clinical Cytogenetics
- Pathology
Accepted Insurances
- Blue Card PPO
- Cigna HMO
- Cigna PPO
- Open Access Plus
- Commercial Insurance Company
- First Choice Health PPO
- HealthSmart
- Medicaid
- Medicare MCR
- ODS Health Plan
- Providence Health Plans
- Preferred Provider Network PPN
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- United Healthcare
- Wells Fargo Insurance
Education
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University of Washington -
University of Maryland School of Medicine
Hospital
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UW Medicine/Harborview Medical Center
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