Physician
General Surgery
Dr. Timothy R. Billiar, MD
Timothy R. Billiar, MD is an expert in the field of General Surgery. He studied medicine at University of Chicago Pritzker School of Medicine. University of Chicago Pritzker School of Medicine is ranked 10 in research and 19 in primary care medicine He received 22 awards: "Distinguished Professor", "Honorary Member Society of Black Academic Surgeons", "Flance-Karl Award", "Elected Member", "Merit Award", "Best Doctors in America", "William S. McEllroy Award", "George Vance Foster Professor and Chair", "Dolph O. Adams Award", "Watson Professor of Surgery", "Alpha Omega Alpha", "George H.A. Clowes Jr Memorial Research Career Development Award", "Samuel P. Harbison Endowed Assistant Professor of Surgery", "Visiting Scholar", "Postdoctoral Fellowship", "Medicine Surgical Award", "Outstanding Alumnus", "Resident Research Awards", "Scholarship", "National Research Service Awards", "Phi Eta Sigma Award" and "Fellow (FACS)". Timothy Billiar is a published physician as well. He has 101 publications published. The latest was: Acute traumatic coagulopathy in a critically-injured pediatric population: Definition, trend over time and outcomes.
Publications
- Regulation of drug-metabolizing enzymes by local and systemic Liver injuries.
- Acute traumatic coagulopathy in a critically-injured pediatric population: Definition, trend over time and outcomes.
- Geographic Variation in Outcome Benefits of Helicopter Transport for Trauma in the United States: A Retrospective Cohort Study.
- Not all prehospital time is equal: Influence of scene time on mortality.
- CT abbreviated assessment of sarcopenia following trauma: The CAAST measurement predicts 6-month mortality in older adult trauma patients.
- Insights into the Role of Chemokines, Damage-Associated Molecular Patterns, and Lymphocyte-derived Mediators from Computational Models of Trauma-Induced Inflammatio...
- Femoral & Experimental.
- The early evolving sex hormone environment is associated with significant outcome and inflammatory response differences after injury.
- Systolic blood pressure criteria in the National Trauma Triage Protocol for geriatric trauma: 110 is the new 90.
- MD-2 is required for disulfide HMGB1-dependent TLR4 signaling.
- Shedding of the tumor necrosis factor (TNF) receptor from the surface of hepatocytes during sepsis limits inflammation through cGMP signaling.
- Neutrophils counteract autophagy-mediated anti-inflammatory mechanisms in alveolar macrophage: role in posthemorrhagic shock acute Lung inflammation.
- High-mobility group box-1 in sterile inflammation.
- Adenosine Deaminase Acting on RNA 1 Limits RIG-I RNA Detection and Suppresses IFN Production Responding to Viral and Endogenous RNAs.
- HMGB1 in health and Disease.
- Evidence-based improvement of the National Trauma Triage Protocol: The Glasgow Coma Scale versus Glasgow Coma Scale motor subscale.
- HMGB1 Phenotypic Role Revealed with Stress.
- Delayed Neutralization of IL-6 Reduces Organ Injury, Selectively Suppresses Inflammatory Mediator and Partially Normalizes Immune Dysfunction following Trauma and Hemo...
- Characterization of the Sex Dimorphism Following Severe Thermal Injury.
- Macrophage endocytosis of high-mobility group box 1 triggers pyroptosis.
- Significant sex-based outcome differences in severely injured chinese trauma patients.
- Pretrauma Center Red Blood Cell Transfusion Is Associated With Reduced Mortality and Coagulopathy in Severely Injured Patients With Blunt Trauma.
- The central role of arginine catabolism in T-cell dysfunction and increased susceptibility to infection after physical injury.
- Prehospital Use of Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Is Associated With a Reduced Incidence of Trauma-Induced Coagulopathy.
- Intracellular Hmgb1 Inhibits Inflammatory Nucleosome Release and Limits Acute Pancreatitis in Mice.
- The swinging pendulum: A national perspective of nonoperative management in severe blunt Liver injury.
- TIFA upregulation after hypoxia-reoxygenation is TLR4- and MyD88-dependent and associated with HMGB1 upregulation and release.
- Eritoran attenuates tissue damage and inflammation in hemorrhagic shock/trauma.
- Molecular analysis of transplant rejection: marching onward.
- Histones Activate the NLRP3 Inflammasome in Kupffer Cells during Sterile Inflammatory Liver Injury.
- Glutathione and thioredoxin type 1 cooperatively denitrosate HepG2 cells-derived cytosolic S-nitrosoproteins.
- Multidisciplinary acute care research organization (MACRO): if you build it, they will come.
- American College of Surgeons trauma center verification versus state designation: are Level II centers slipping through the cracks?
- Selective roles for toll-like receptors 2, 4, and 9 in systemic inflammation and immune dysfunction following Peripheral tissue injury.
- Hydrogen gas reduces hyperoxic Lung injury via the Nrf2 pathway in vivo.
- CD14 Contributes to Warm Hepatic Ischemia-Reperfusion Injury in Mice.
- Goal-directed resuscitation in the prehospital setting: A propensity-adjusted analysis.
- Endothelial TLR4 activation impairs Intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS-NO-nitrite signaling.
- Hemorrhagic Shock Augments Nlrp3 Inflammasome Activation in the Lung through Impaired Pyrin Induction.
- Lipopolysaccharide Clearance, Bacterial Clearance, and Systemic Inflammatory Responses Are Regulated by Cell Type-Specific Functions of TLR4 during Sepsis.
- Cellular specific role of toll-like receptor 4 in hepatic ischemia-reperfusion injury.
- PEX7 and EBP50 target iNOS to the peroxisome in hepatocytes.
- Signaling of High Mobility Group Box 1 (HMGB1) through Toll-like Receptor 4 in Macrophages Requires CD14.
- A novel method of preserving cardiac grafts using a hydrogen-rich water bath.
- Role of Heme Oxygenase-1 in TNF/TNF Receptor-Mediated Apoptosis After Hepatic Ischemia/Reperfusion in Rats.
- Genomic responses in mouse models poorly mimic human inflammatory Diseases.
- High mobility group Box 1 inhibits human pulmonary artery endothelial cell migration via a Toll-like receptor 4- and interferon response factor 3-dependent mechanism(s).
- The HMGB1/RAGE inflammatory pathway promotes pancreatic tumor growth by regulating mitochondrial bioenergetics.
- High Mobility Group Box 1 Contributes to the Pathogenesis of Experimental Pulmonary Hypertension via Activation of Toll-like Receptor 4.
- Interferon Regulatory Factor-1 Regulates the Autophagic Response in LPS Stimulated Macrophages through Nitric Oxide.
- Assessment of platelet transfusion for reversal of aspirin after traumatic brain injury.
- Hydrogen-Enriched Preservation Protects the Isogeneic Intestinal Graft and Amends Recipient Gastric Function During Transplantation.
- Hemorrhagic Shock Activation of NLRP3 Inflammasome in Lung Endothelial Cells.
- Mast Cells Play a Critical Role in the Systemic Inflammatory Response and End-Organ Injury Resulting from Trauma.
- TRANSCRIPTOMIC RESPONSE OF MURINE Liver TO SEVERE INJURY AND HEMORRHAGIC SHOCK: A DUAL PLATFORM MICROARRAY ANALYSIS.
- The effect of donor treatment with hydrogen on Lung allograft function in rats.
- Sepsis: Something old, something new, and a systems view.
- Characterization of DISC Formation and TNFR1 Translocation to Mitochondria in TNF-Treated Hepatocytes.
- High-mobility group box 1 is essential for mitochondrial quality control.
- Caspase-1 is hepatoprotective during trauma and hemorrhagic shock by reducing Liver injury and inflammation.
- Early lower extremity Fracture fixation and the risk of early pulmonary embolus: filter before fixation?
- Hypoxia-induced overexpression of BNIP3 is not dependent on hypoxia-inducible factor 1α in mouse hepatocytes.
- Hydrogen inhalation reduced epithelial apoptosis in ventilator-induced Lung injury via a mechanism involving nuclear factor-kappa B activation.
- DNA attenuates enterocyte Toll-like receptor 4-mediated Intestinal mucosal injury after remote trauma.
- Models of lower extremity damage in mice: time course of organ damage and immune response.
- Interferon regulatory factor 1 mediates acetylation and release of high mobility group box 1 from hepatocytes during murine Liver ischemia-reperfusion injury.
- Hemorrhagic shock activates Lung endothelial reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase via neutrophil NADPH oxidase.
- Role of hemorrhage in the induction of systemic inflammation and remote organ damage: analysis of combined pseudo-Fracture and hemorrhagic shock.
- Systemic inflammation and Liver injury following hemorrhagic shock and peripheral tissue trauma involve functional TLR9 signaling on bone marrow-derived cells and pare...
- Over reliance on computed tomography imaging in patients with severe abdominal injury: is the delay worth the risk?
- Hydrogen therapy may reduce the risks related to radiation-induced oxidative stress in space flight.
- Complement c3 deficiency attenuates chronic hypoxia-induced pulmonary hypertension in mice.
- TNF/TNF receptor 1-mediated apoptosis in hepatocytes.
- Fixed volume or fixed pressure: a murine model of hemorrhagic shock.
- A dynamic view of trauma/hemorrhage-induced inflammation in mice: principal drivers and networks.
- Inhaled hydrogen gas therapy for prevention of Lung transplant-induced ischemia/reperfusion injury in rats.
- Differential regulation by fucoidan of IFN-γ-induced NO production in glial cells and macrophages.
- Complement factor 3 deficiency attenuates hemorrhagic shock-related hepatic injury and systemic inflammatory response syndrome.
- Incidental radiographic findings after injury: dedicated attention results in improved capture, documentation, and management.
- Pivotal advance: The pattern recognition receptor ligands lipopolysaccharide and polyinosine-polycytidylic acid stimulate factor B synthesis by the macrophage through ...
- A critical role for IFN regulatory factor 1 in NKT cell-mediated Liver injury induced by alpha-galactosylceramide.
- Superior myocardial preservation with HTK solution over Celsior in rat hearts with prolonged cold ischemia.
- Dominant role of the MyD88-dependent signaling pathway in mediating early endotoxin-induced murine ileus.
- Delay to therapeutic interventional radiology postinjury: time is of the essence.
- Amelioration of rat cardiac cold ischemia/reperfusion injury with inhaled hydrogen or carbon monoxide, or both.
- The nitric oxide donor S-nitrosoglutathione reduces apoptotic primary Liver cell loss in a three-dimensional perfusion bioreactor culture model developed for Liver sup...
- Oral hydrogen water prevents chronic allograft nephropathy in rats.
- Nitric oxide and thioredoxin type 1 modulate the activity of caspase 8 in HepG2 cells.
- Hemorrhagic shock augments Lung endothelial cell activation: role of temporal alterations of TLR4 and TLR2.
- Low-dose cisplatin administration in murine cecal ligation and puncture prevents the systemic release of HMGB1 and attenuates lethality.
- Orally administered nitrite attenuates cardiac allograft rejection in rats.
- Preactivation of NKT cells with alpha-GalCer protects against hepatic ischemia-reperfusion injury in mouse by a mechanism involving IL-13 and adenosine A2A receptor.
- Activation of latent transforming growth factor-beta1 by nitric oxide in macrophages: role of soluble guanylate cyclase and MAP kinases.
- Mechanisms of Toll-like receptor 4 (TLR4)-mediated inflammation after cold ischemia/reperfusion in the heart.
- Endotoxin uptake in mouse Liver is blocked by endotoxin pretreatment through a suppressor of cytokine signaling-1-dependent mechanism.
- Expression and subcellular localization of BNIP3 in hypoxic hepatocytes and Liver stress.
- Innate immune mechanisms in ischemia/reperfusion.
- Possible novel therapy for malignant gliomas with secretable trimeric TRAIL.
- An adequately robust early TNF-alpha response is a hallmark of survival following trauma/hemorrhage.
- Interacting neuroendocrine and innate and acquired immune pathways regulate neutrophil mobilization from bone marrow following hemorrhagic shock.
Schools
U Of Chgo Div Of Bio Sci Pritzker Sch Of Med
Procedures Preformed
- Appendectomy, Laparoscopic
- Embolectomy, Thrombectomy, or Vessel Exploration
- Fecal Impaction Removal
- Laparotomy
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Conditions Treated
- Appendicitis
- Cholecystitis and Gallstones
- Collapsed Lung (Pneumothorax)
- Crohn's Disease (Regional Enteritis)
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Doctors Specialties
Accepted Insurances
Awards
- Distinguished Professor
- Honorary Member Society of Black Academic Surgeons
- Flance-Karl Award
- Elected Member
- Merit Award
- Best Doctors in America
- William S. McEllroy Award
- George Vance Foster Professor and Chair
- Dolph O. Adams Award
- Watson Professor of Surgery
- Alpha Omega Alpha
- George H.A. Clowes Jr Memorial Research Career Development Award
- Samuel P. Harbison Endowed Assistant Professor of Surgery
- Visiting Scholar
- Postdoctoral Fellowship
- Medicine Surgical Award
- Outstanding Alumnus
- Resident Research Awards
- Scholarship
- National Research Service Awards
- Phi Eta Sigma Award
- Fellow (FACS)
Education
-
University of Pittsburgh Medical Center
-
University of Minnesota at Fairview
-
University of Chicago Pritzker School of Medicine
Hospital
-
UPMC Presbyterian Shadyside
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Medicare Facts
| National Provider Identifier [NPI] |
1598737330 |
| Last Name Of The Provider |
BILLIAR |
| First Name Of The Provider |
TIMOTHY |
| View All |
|
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