Assistant Professor of Pediatrics and Genetics
Pediatric Hematology & Oncology
Dr. Todd E. Druley, MD
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Doctor Todd E. Druley, MD works in the field of Pediatric Hematology & Oncology. He went to medical school at Washington University School of Medicine. He has 12 awards "Clinical Scientist Development Award", "Hyundai Hope Grant recipient", "Alexs Lemonade Stand A Award", "Childrens Discovery Institute Faculty Scholar", "Hyundai Hope on Wheels Scholar in Pediatric Oncology", "Scholar of the NIH Child Health Research Center for Developmental Biology", "Member of the Siteman Cancer Center, NIH Comprehensive Cancer Center", "Mark Johnston Scholar in the Genome Sciences", "Outstanding Fellow Teaching", "Rated third best thesis", "University Distinction for Research in Cell and Structural Biology" and "Children of Vietnam Veterans Merit Scholarship". Doctor Todd E. Druley, MD is also published. He has 25 publications published. The lastest publication: "P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity.'
Publications
- Quantifying ultra-rare pre-leukemic clones via targeted error-corrected sequencing.
- Role of TP53 mutations in the origin and evolution of therapy-related Acute myeloid leukaemia.
- The cyclic AMP pathway is a sex-specific modifier of glioma risk in type 1 neurofibromatosis patients.
- Late Toxicity of a Novel Allogeneic Stem Cell Transplant Using Single Fraction Total Body Irradiation for Hematologic Malignancies in Children.
- Excess congenital non-synonymous variation in Leukemia-associated genes in MLL- infant Leukemia: a Children's Oncology Group report.
- Multiplexed direct genomic selection (MDiGS): a pooled BAC capture approach for highly accurate CNV and SNP/INDEL detection.
- Synonymous ABCA3 Variants Do Not Increase Risk for Neonatal Respiratory Distress Syndrome.
- Integrated analysis of germline and somatic variants in ovarian Cancer.
- Genetic variation in MKL2 and decreased downstream PCTAIRE1 expression in extreme, fatal primary human microcephaly.
- Single ABCA3 mutations increase risk for neonatal respiratory distress syndrome.
- High-throughput discovery of rare insertions and deletions in large cohorts.
- Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with Disease.
- Severe ceftriaxone-induced hemolysis complicated by diffuse cerebral ischemia in a child with sickle cell Disease.
- Quantification of rare allelic variants from pooled genomic DNA.
- Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence.
- Myosin binding protein C1: a novel gene for autosomal dominant distal arthrogryposis type 1.
- Herbaspirillum species bacteremia in a pediatric oncology patient.
- P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity.
- Analysis of MDR1 P-glycoprotein conformational changes in permeabilized Cells using differential immunoreactivity.
- P-glycoprotein-mediated colchicine resistance in different Cell lines correlates with the effects of colchicine on P-glycoprotein conformation.
- From MDR to MXR: new understanding of multidrug resistance Systems, their properties and clinical significance.
- Early outcomes after allogeneic hematopoietic SCT in pediatric patients with hematologic malignancies following single fraction TBI.
- Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Fa...
- Pooled Sequencing of Candidate Genes Implicates Rare Variants in the Development of Asthma Following Severe RSV Bronchiolitis in Infancy.
Schools
University of Illinois At Chicago College of Medicine
St Louis Childrens Hospital
Conditions Treated
- Acute Leukemia
- Anemia
- Brain and Nervous System Cancer (incl. Gliomas, Astrocytoma, Schwannoma, Medulloblastoma, Chordoma)
- Brain Cancer
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Doctors Specialties
- Pediatric Hematology
- Oncology
Accepted Insurances
Awards
- Clinical Scientist Development Award
- Hyundai Hope Grant recipient
- Alex’s Lemonade Stand “A†Award
- Children’s Discovery Institute Faculty Scholar
- Hyundai Hope on Wheels Scholar in Pediatric Oncology
- Scholar of the NIH Child Health Research Center for Developmental Biology
- Member of the Siteman Cancer Center, NIH Comprehensive Cancer Center
- Mark Johnston Scholar in the Genome Sciences
- Outstanding Fellow Teaching
- Rated third best thesis
- University Distinction for Research in Cell and Structural Biology
- Children of Vietnam Veterans Merit Scholarship
Education
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Washington University School of Medicine -
University of Illinois College of Medicine -
University of Illinois at Chicago -
University of Illinois at Urbana-Champaign
Hospital
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Barnes-Jewish Hospital -
St. Louis Children's Hospital
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