Physician
Nephrology
Dr. Virginia J. Savin, MD
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Dr. Virginia J. Savin works in the field of Nephrology. She went to University of Pittsburgh School of Medicine. She received awards:"Elected Member". Virginia J. Savin, MD has written publications. She has 84 publications published with PubMed. The lastest publication is: 'Plasmapheresis in the treatment of steroid-resistant focal segmental glomerulosclerosis in native kidneys.'
Publications
- Normalization of testosterone level is associated with reduced incidence of myocardial infarction and mortality in men.
- Ethanol at low concentrations protects glomerular podocytes through alcohol dehydrogenase and 20-HETE.
- CYCLOOXYGENASE-2, PROSTAGLANDIN E2 AND PROSTANOID RECEPTOR EP2 IN FLUID FLOW SHEAR STRESS MEDIATED INJURY IN SOLITARY Kidney.
- Galactose treatment in focal segmental glomerulosclerosis.
- Endothelin-1 increases glomerular permeability and inflammation independent of blood pressure in the rat.
- Circulating permeability factors in idiopathic nephrotic syndrome and focal segmental glomerulosclerosis.
- The urine proteome for radiation biodosimetry: effect of total body vs. local Kidney irradiation.
- Plasma "factors" in recurrent nephrotic syndrome after Kidney transplantation: causes or consequences of glomerular injury?
- Antibodies to protein tyrosine phosphatase receptor type O (PTPro) increase glomerular albumin permeability (P(alb)).
- ADMA injures the glomerular filtration barrier: role of nitric oxide and superoxide.
- 8,9-Epoxyeicosatrienoic acid protects the glomerular filtration barrier.
- The Urine Proteome as a Biomarker of Radiation Injury: Submitted to Proteomics- Clinical Applications Special Issue: "Renal and Urinary Proteomics (Thongboonkerd)...
- Galactose binds to focal segmental glomerulosclerosis permeability factor and inhibits its activity.
- Serum permeability activity in steroid-resistant minimal change nephrotic syndrome is abolished by treatment of Hodgkin Disease.
- Chronically increased intrarenal angiotensin II causes nephropathy in an animal model of type 2 diabetes.
- Arachidonic acid metabolites mediate the radiation-induced increase in glomerular albumin permeability.
- Nitric oxide preserves the glomerular protein permeability barrier by antagonizing superoxide.
- Transforming growth factor-beta, 20-HETE interaction, and glomerular injury in Dahl salt-sensitive rats.
- Glomerular permeability activity: prevalence and prognostic value in pediatric patients with idiopathic nephrotic syndrome.
- The focal segmental glomerulosclerosis permeability factor: biochemical characteristics and biological effects.
- Permeability factors in focal segmental glomerulosclerosis.
- Serial estimates of serum permeability activity and clinical correlates in patients with native Kidney focal segmental glomerulosclerosis.
- Proteinuria after injection of human focal segmental glomerulosclerosis factor.
- Induction of metallothionein-I protects glomeruli from superoxide-mediated increase in albumin permeability.
- Nephropathy in heroin addicts with staphylococcal septicemia.
- Phosphorus-enriched hemodialysis during pregnancy: Two case reports.
- Glomerular adaptation in uninephrectomized young rats.
- Follow-up of phase I trial of adalimumab and rosiglitazone in FSGS: III. Report of the FONT study group.
- Novel therapies for resistant focal segmental glomerulosclerosis (FONT) phase II clinical trial: study design.
- Effect of gentamicin on isolated glomeruli and proximal tubules of the rabbit.
- Markers of masked iron deficiency and effectiveness of EPO therapy in Chronic renal failure.
- Inhibitory effect of Tripterygium wilfordii multiglycoside on increased glomerular albumin permeability in vitro.
- Circulating factor in patients with recurrent focal segmental glomerulosclerosis postrenal transplantation inhibits expression of inducible nitric oxide synthase and n...
- Proximal tubule volume regulation in hyperosmotic media: intracellular K+, Na+, and Cl-.
- Phase 1 trial of adalimumab in Focal Segmental Glomerulosclerosis (FSGS): II. Report of the FONT (Novel Therapies for Resistant FSGS) study group.
- Plasmapheresis in the treatment of steroid-resistant focal segmental glomerulosclerosis in native Kidneys.
- Renal structural-functional relationships in early diabetes mellitus.
- Direct effects of platelet-activating factor on glomerular capillary permeability.
- Cyclosporine protects glomeruli from FSGS factor via an increase in glomerular cAMP.
- Matrix metalloproteinase (stromelysin-1) increases the albumin permeability of isolated rat glomeruli.
- Alteration of glomerular permeability to macromolecules induced by cross-linking of beta 1 integrin receptors.
- Cyclosporine prevents the increase in glomerular albumin permeability caused by serum from patients with focal segmental glomerular sclerosis.
- Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerulosclerosis.
- Mechanisms of proteinuria in noninflammatory glomerular Diseases.
- Effect of superoxide exposure on albumin permeability of isolated rat glomeruli.
- Plasmapheresis reduces proteinuria and serum capacity to injure glomeruli in patients with recurrent focal glomerulosclerosis.
- Polymorphonuclear leukocytes increase glomerular albumin permeability via hypohalous acid.
- Sodium nitroprusside increases glomerular capillary hydraulic conductivity in isolated rat glomeruli.
- C5b-9 increases albumin permeability of isolated glomeruli in vitro.
- Filtration in single isolated mammalian glomeruli.
- Ultrafiltration coefficient and glomerular capillary resistance a model of immune complex glomerulonephritis.
- Decreased ultrafiltration coefficient of glomeruli isolated from volume-depleted rats.
- Ultrafiltration in single isolated human glomeruli.
- Glomerular ultrafiltration coefficient after ischemic renal injury in dogs.
- Communication of affect through facial expressions in humans.
- Filtration by superficial and deep glomeruli of normovolemic and volume-depleted rats.
- In vitro effects of angiotensin II on glomerular function.
- Filtration by rat glomeruli after expansion of extracellular fluid volume.
- Ultrafiltration coefficients of glomeruli from human biopsies.
- The use of video imaging techniques to study ultrafiltration and blood flow in the normal and diseased Kidney.
- Percutaneous transluminal angioplasty in transplant renal artery stenosis: experience and review of the literature.
- Dietary protein and glomerular response to subtotal nephrectomy in the rat.
- Glomerular effects of angiotensin II require intrarenal factors.
- In vitro effects of cyclosporine on glomerular function.
- Diminished glomerular capillary hydraulic conductivity precedes morphologic changes in experimental diabetes mellitus in the rat.
- Measurement of albumin reflection coefficient with isolated rat glomeruli.
- Vasoactive substances induce cytoskeletal changes in cultured rat glomerular epithelial cells.
- Renal transplantation. A decade of experience.
- "The FSGS factor:" enrichment and in vivo effect of activity from focal segmental glomerulosclerosis plasma.
- Ultrafiltration coefficient of isolated glomeruli of rats aged 4 days to maturation.
- Effective use of streptokinase for peritoneal catheter failure.
- Recurrent and de novo renal Diseases after renal transplantation: a report from the renal allograft disease registry.
- Documentation of angiotensin II receptors in glomerular epithelial cells.
- TNF-alpha increases albumin permeability of isolated rat glomeruli through the generation of superoxide.
- Both subtype 1 and 2 receptors of angiotensin II participate in regulation of intracellular calcium in glomerular epithelial cells.
- Early detection of radiation-induced glomerular injury by albumin permeability assay.
- Components of normal serum block the focal segmental glomerulosclerosis factor activity in vitro.
- Transforming growth factor-beta1 increases albumin permeability of isolated rat glomeruli via hydroxyl radicals.
- Recurrent and de novo Disease after renal transplantation: a report from the Renal Allograft Disease Registry.
- Chymase increases glomerular albumin permeability via protease-activated receptor-2.
- Recurrence of proteinuria following renal transplantation in Congenital nephrotic syndrome of the Finnish type.
- Preemptive plasmapheresis and recurrence of FSGS in high-risk renal transplant recipients.
- Endothelin receptor A-specific stimulation of glomerular inflammation and injury in a streptozotocin-induced rat model of diabetes.
Schools
University of Pittsburgh School of Medicine
Dc General Hospital Georgetown Division
DC General Hospital
University of Washington
Conditions Treated
- Amyloidosis
- Chronic Kidney Diseases
- Congenital Cystic Kidney Disease
- Hypertension
- View All
Doctors Specialties
- Nephrology
Accepted Insurances
Awards
- Elected Member
Education
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Duke University Hospital -
University of Pittsburgh School of Medicine
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