Professor of Oncology, Johns Hopkins University School of Medicine; Associate Professor of Oncology
Oncology
Dr. William H. Matsui, MD
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William Matsui is an expert in the field of Oncology. He researched medicine at University of California San Francisco School of Medicine. University of California San Francisco School of Medicine is a one of the best medicals schools. University of California San Francisco School of Medicine is ranked 3 in research and 3 in primary care medicine He received awards:"Elected Member", "Leukemia and Lymphoma Society Scholar in Clinical Research", "Kimmel Foundation Scholar", "Teaching Award", "Career Development Award", "Clinician Scientist Award", "Presentation Award", "The George Santos Researcher at Johns Hopkins", "Leukemia and Lymphoma Society Fellow", "Young Investigator Award", "Howard Hughes Medical Institute Student Research Fellowship", "Dean's Summer Research Fellowship", "Dean's Prize for Medical Student Research", "Thomas T. Hoopes Prize for Undergraduate Academic Excellence" and "Harvard College Scholarship". William H. Matsui, MD is also a published doctor. He has 91 paper published. The most recent paper is: Glucocorticoid receptor transcriptional activity determined by spacing of receptor and nonreceptor DNA sites. He is registered with Medicare.
Publications
- Risk-stratified outcomes of nonmyeloablative, HLA-haploidentical BMT with high-dose posttransplantation cyclophosphamide.
- Post-transplantation cyclophosphamide as single-agent GVHD prophylaxis after myeloablative conditioning and HLA-matched allografting for Acute leukemias and myelodyspl...
- Activation of liver x receptors inhibits hedgehog signaling, clonogenic growth, and self-renewal in multiple Myeloma.
- Granulocyte-macrophage colony stimulating factor (GM-CSF) enhances the clinical responses to interferon-α (IFN) in newly diagnosed chronic myeloid Leukemia (CML).
- Growth Differentiating Factor 15 enhances the tumor initiating and self-renewal potential of multiple myeloma Cells.
- A bis-Benzylidine Piperidone Targeting Proteasome Ubiquitin Receptor RPN13/ADRM1 as a Therapy for Cancer.
- DCLK1 Marks a Morphologically Distinct Subpopulation of Cells with Stem Cell Properties in Pre-invasive Pancreatic Cancer.
- Absence of Post-Transplantation Lymphoproliferative Disorder after Allogeneic Blood or Marrow Transplantation Using Post-Transplantation Cyclophosphamide as Graft-vers...
- Brief intensive therapy for older adults with newly diagnosed Burkitt or atypical Burkitt lymphoma/Leukemia.
- Tumorigenic potential of circulating prostate tumor Cells.
- Chloroquine improves survival and hematopoietic recovery after lethal low-dose-rate radiation.
- Heterogeneity and targeting of pancreatic cancer stem Cells.
- A combination of DR5 agonistic monoclonal antibody with gemcitabine targets pancreatic cancer stem cells and results in long-term Disease control in human pancreatic c...
- Nonmyeloablative HLA-haploidentical bone marrow transplantation with high-dose posttransplantation cyclophosphamide: effect of HLA disparity on outcome.
- High-dose cyclophosphamide for severe aplastic Anemia: long-term follow-up.
- Graft-versus-host reactions and the effectiveness of donor lymphocyte infusions.
- Association of Foxp3 regulatory gene expression with Graft-versus-host disease.
- Cancer stem Cells: are we missing the target?
- The role of growth factors in the activity of pharmacological differentiation agents.
- Hypoxia increases the expression of stem-Cell markers and promotes clonogenicity in glioblastoma neurospheres.
- Tumor-initiating Cells are rare in many human tumors.
- Telomerase inhibition targets clonogenic multiple myeloma Cells through telomere length-dependent and independent mechanisms.
- Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem Cells.
- Isolation of stem cells from human pancreatic cancer xenoGrafts.
- Characterization of chronic myeloid Leukemia stem cells.
- Hedgehog signaling in hematopoiesis.
- Self-renewal of Acute lymphocytic leukemia cells is limited by the Hedgehog pathway inhibitors cyclopamine and IPI-926.
- Concise review: Emerging concepts in clinical targeting of cancer stem Cells.
- Development and maintenance of cancer stem cells under Chronic inflammation.
- High-dose cyclophosphamide and rituximab without stem cell transplant: a feasibility study for low grade B-cell, transformed and mantle cell Lymphomas.
- Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenoGraft models.
- The redox-sensitive transcription factor, Nrf2, regulates murine hematopoietic stem Cell survival independent of ROS levels.
- Perspective: A model Disease.
- Autologous stem Cell transplantation and multiple myeloma cancer stem Cells.
- Cancer stem Cells: relevance to clinical transplantation.
- Biological and clinical relevance of stem Cells in pancreatic adenocarcinoma.
- Gli1 regulates the proliferation and differentiation of HSCs and Myeloid progenitors.
- High-dose cyclophosphamide as single-agent, short-course prophylaxis of Graft-versus-host disease.
- Prognostic significance of tumorigenic Cells with mesenchymal features in pancreatic adenocarcinoma.
- Multiple myeloma: a paradigm for translation of the cancer stem Cell hypothesis.
- Targeting Hedgehog--a cancer stem Cell pathway.
- Mantle cell Lymphoma activation enhances bortezomib sensitivity.
- Urothelial carcinoma: stem Cells on the edge.
- Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic Cancer.
- Higher serum folate levels are associated with a lower risk of atopy and wheeze.
- Smoothening the controversial role of hedgehog in hematopoiesis.
- DNER, an epigenetically modulated gene, regulates glioblastoma-derived neurosphere Cell differentiation and tumor propagation.
- Differentiation of a highly tumorigenic basal Cell compartment in urothelial carcinoma.
- Cancer stem Cells: controversies in multiple myeloma.
- Activated marrow-infiltrating lymphocytes effectively target plasma Cells and their clonogenic precursors.
- Requirement for myeloid growth factors in the differentiation of Acute promyelocytic leukaemia.
- Do neoplastic stem cells underlie the pathogenesis of cutaneous Lymphomas?
- Effects of imatinib and interferon on primitive Chronic myeloid leukaemia progenitors.
- The paradox of response and survival in Cancer therapeutics.
- Anti-tumour activity of interferon-alpha in multiple myeloma: role of interleukin 6 and tumor Cell differentiation.
- Characterization of clonogenic multiple myeloma Cells.
- Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer Cells in glioblastoma.
- Induction of autologous graft-versus-host disease: results of a randomized prospective clinical trial in patients with poor risk Lymphoma.
- The multiple myeloma associated MMSET gene contributes to Cellular adhesion, clonogenic growth, and tumorigenicity.
- Therapeutic implications of leukemic stem Cell pathways.
- Clonogenic multiple myeloma progenitors, stem Cell properties, and drug resistance.
- Myeloablative allogeneic bone marrow transplant using T cell depleted alloGrafts followed by post-transplant GM-CSF in high-risk myelodysplastic syndromes.
- HLA-haploidentical bone marrow transplantation for hematologic Malignancies using nonmyeloablative conditioning and high-dose, posttransplantation cyclophosphamide.
- Multiple myeloma cancer stem Cells.
- An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic Cancer.
- Cancer stem Cells in multiple myeloma.
- Notch pathway inhibition depletes stem-like cells and blocks enGraftment in embryonal brain tumors.
- Blockade of hedgehog signaling inhibits pancreatic Cancer invasion and metastases: a new paradigm for combination therapy in solid Cancers.
- Hedgehog signaling maintains a tumor stem Cell compartment in multiple myeloma.
- Glycosylphosphatidylinositol-anchored protein deficiency confers resistance to apoptosis in PNH.
- A direct pancreatic cancer xenoGraft model as a platform for cancer stem cell therapeutic development.
- Achaete-scute complex homologue 1 regulates tumor-initiating capacity in human small Cell lung cancer.
- Circulating clonotypic B cells in classic Hodgkin Lymphoma.
- GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein.
- Enhanced cytotoxicity of rituximab following genetic and biochemical disruption of glycosylphosphatidylinositol anchored proteins.
- Strategies to eliminate cancer stem Cells: clinical implications.
- Differentiation therapy in poor risk Myeloid malignancies: Results of a dose finding study of the combination bryostatin-1 and GM-CSF.
- Immunologic recovery following autologous stem-cell transplantation with pre- and posttransplantation rituximab for low-grade or mantle cell Lymphoma.
- Stabilization of clathrin coats by the core of the clathrin-associated protein complex AP-2.
- Structural and functional division into two domains of the Large (100- to 115-kDa) chains of the clathrin-associated protein complex AP-2.
- [Diagnosis of malignant thyroid tumor using high-frequency ultrasonography with piezoelectric transducer, Soft X-rays and aspiration biopsy cytology].
- Inhibition of the multidrug efflux pump in isolated hepatocyte couplets by immunosuppressants FK506 and cyclosporine.
- [An evaluation of the hemodynamics in metastatic liver tumor by using ultrasound color Doppler flow mapping examination].
- IntraCellular receptors use a common mechanism to interpret signaling information at response elements.
- [Idiopathic superior mesenteric venous thrombosis--a case report].
- Glucocorticoid receptor transcriptional activity determined by spacing of receptor and nonreceptor DNA sites.
- Cancer stem Cells: relevance to SCT.
- Induction of Acute lymphocytic leukemia differentiation by maintenance therapy.
- Salvage transplantation for alloGraft failure using fludarabine and alemtuzumab as conditioning regimen.
- Quantitative analysis of bone marrow CD34 cells in aplastic Anemia and hypoplastic myelodysplastic syndromes.
Schools
University of California At San Francisco
Johns Hopkins University School Med
University Of Wa School Of Med
Procedures Preformed
- Bone Marrow Transplant
- HPC Transplantation (Stem Cell Transplant)
- Thoracentesis
Conditions Treated
- Acute Leukemia
- Anemia
- Central Nervous System Lymphoma
- Chronic Myeloid Leukemia (CML)
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Doctors Specialties
- Medical Oncology
- Oncology
Accepted Insurances
Awards
- Elected Member
- Leukemia and Lymphoma Society Scholar in Clinical Research
- Kimmel Foundation Scholar
- Teaching Award
- Career Development Award
- Clinician Scientist Award
- Presentation Award
- The George Santos Researcher at Johns Hopkins
- Leukemia and Lymphoma Society Fellow
- Young Investigator Award
- Howard Hughes Medical Institute Student Research Fellowship
- Dean's Summer Research Fellowship
- Dean's Prize for Medical Student Research
- Thomas T. Hoopes Prize for Undergraduate Academic Excellence
- Harvard College Scholarship
Education
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Johns Hopkins University -
University of Washington -
University of California San Francisco School of Medicine -
Harvard College
Hospital
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Johns Hopkins Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1568411049 |
| Last Name Of The Provider | MATSUI |
| First Name Of The Provider | WILLIAM |
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